Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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MuSE: A deep learning model based on multi-feature fusion for super-enhancer prediction.

Although bioinformatics-based methods accurately identify SEs (Super-enhancers), the results depend ...

Nov 2024 39561516
Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing.

The rapid growth of single-cell transcriptomic technology has produced an increasing number of datas...

Nov 2024 39543284
Neural network-based predictions of antimicrobial resistance phenotypes in multidrug-resistant from whole genome sequencing and gene expression.

Whole genome sequencing (WGS) potentially represents a rapid approach for antimicrobial resistance g...

Nov 2024 39540735
Machine learning-driven estimation of mutational burden highlights DNAH5 as a prognostic marker in colorectal cancer.

BACKGROUND: Tumor Mutational Burden (TMB) have emerged as pivotal predictive biomarkers in determini...

Nov 2024 39543663
Visualization Methods for DNA Sequences: A Review and Prospects.

The efficient analysis and interpretation of biological sequence data remain major challenges in bio...

Nov 2024 39595624
Early and noninvasive prediction of response to neoadjuvant therapy for breast cancer via longitudinal ultrasound and MR deep learning: A multicentre study.

RATIONALE AND OBJECTIVES: The early prediction of response to neoadjuvant chemotherapy (NAC) will ai...

Nov 2024 39542804
Barley Grain Proteome Assessment Using Multi-Environment Trial Data and Machine Learning.

Proteomics can be used to assess individual protein abundances, which could reflect genotypic and en...

Nov 2024 39536264
Deep learning enables the use of ultra-high-density array in DNBSEQ.

DNBSEQ employs a patterned array to facilitate massively parallel sequencing of DNA nanoballs (DNBs)...

Nov 2024 39537672
Investigating Ligand-Mediated Conformational Dynamics of Pre-miR21: A Machine-Learning-Aided Enhanced Sampling Study.

MicroRNAs (miRs) are short, noncoding RNA strands that regulate the activity of mRNAs by affecting t...

Nov 2024 39526676
Discovery of key molecular signatures for diagnosis and therapies of glioblastoma by combining supervised and unsupervised learning approaches.

Glioblastoma (GBM) is the most malignant brain cancer and one of the leading causes of cancer-relate...

Nov 2024 39528802
Improving methylmalonic acidemia (MMA) screening and MMA genotype prediction using random forest classifier in two Chinese populations.

BACKGROUND: Methylmalonic acidemia (MMA) is one of the most common hereditary organic acid metabolis...

Nov 2024 39523381
Interpretation knowledge extraction for genetic testing via question-answer model.

BACKGROUND: Sequencing-based genetic testing is widely used in biomedical research, including pathog...

Nov 2024 39522019
Deep Learning-Based Classification of Macrofungi: Comparative Analysis of Advanced Models for Accurate Fungi Identification.

This study focuses on the classification of six different macrofungi species using advanced deep lea...

Nov 2024 39598966
DeSide: A unified deep learning approach for cellular deconvolution of tumor microenvironment.

Cellular deconvolution via bulk RNA sequencing (RNA-seq) presents a cost-effective and efficient alt...

Nov 2024 39514318
Deep learning method for detecting fluorescence spots in cancer diagnostics via fluorescence in situ hybridization.

Fluorescence in Situ Hybridization (FISH) is a technique for macromolecule identification that utili...

Nov 2024 39516673
A deep learning model for prediction of autism status using whole-exome sequencing data.

Autism is a developmental disability. Research demonstrated that children with autism benefit from e...

Nov 2024 39514604
Machine Learning-enhanced Signature of Metastasis-related T Cell Marker Genes for Predicting Overall Survival in Malignant Melanoma.

In this study, we aimed to investigate disparities in the tumor immune microenvironment (TME) betwee...

Nov 2024 39506915
Challenges and Prospects of DNA-Encoded Library Data Interpretation.

DNA-encoded library (DEL) technology is a powerful platform for the efficient identification of nove...

Nov 2024 39508428
Effect of graphene electrode functionalization on machine learning-aided single nucleotide classification.

Solid-state nanogap-based DNA sequencing with a quantum tunneling approach has emerged as a promisin...

Nov 2024 39392717
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