Genetics

Research on a novel gene sequence prediction and homomorphic encryption method based on Mamba-VMD.

Gene sequence prediction not only effectively identifies homologous genes but also provides crucial ...

Benchmarking AlphaMissense against ClinVar for Diagnostic Interpretation of Missense Variants in Inherited Retinal Diseases.

PURPOSE: AlphaMissense is a newer deep learning-based variant predictor that evaluates the structura...

Pathologic assessment of resected stage III non-small cell lung cancer after neoadjuvant chemotherapy: identification of additional prognostic factors.

BACKGROUND: Non-small cell lung cancer (NSCLC) patients undergoing neoadjuvant chemotherapy (NACT) f...

Structure-Based Classification of CRISPR/Cas9 Proteins: A Machine Learning Approach to Elucidating Cas9 Allostery.

The CRISPR/Cas9 system is a powerful gene-editing tool. Its specificity and stability rely on comple...

KLF7 as a biomarker for the pre-metastatic state promotes colorectal cancer liver metastasis via TGFβ autocrine signaling.

Although metastasis-initiating cells drive metastasis, only a certain subpopulation of these cells c...

Zoonoticus: A machine learning model for genomic prediction of zoonotic bacterial strains using virulence, resistance, and mobile genetic elements.

Zoonotic diseases continue to rise globally, yet no existing genomic tool integrates virulence, anti...

Corrigendum to 'Decoding Epigenetic Enhancer-Promoter Interactions in Periodontitis via Transformer-GAN: A Deep Learning Framework for Inflammatory Gene Regulation and Biomarker Discovery' [International Dental Journal Volume 75, Issue 6, December 2025, 103879].

Bioelectrochemical mitigation of soil antibiotic resistance: Disruption of bacteriophage transmission and resistant hosts.

The proliferation of antibiotic resistance genes (ARGs) in environment poses a threat to global publ...

Automatically Measuring Kidney, Liver, and Cyst Volumes in Autosomal Dominant Polycystic Kidney Disease.

KEY POINTS: TraceOrg is a web-based tool that automatically labels kidney, liver, and cysts, reporti...

Genetic Determinants and Breeding Strategies for Rice Cooking and Eating Quality: A Comprehensive Review.

Rice cooking and eating quality (CEQ), a core agronomic trait tied to consumer preference and market...

Multi-omics technologies: Novel tools and methods for assessing nerve injury and regeneration.

Recently, with the rapid advancement of multi-omics technologies, including genomics, transcriptomic...

Single-Cell and Machine Learning Analysis Reveal Novel Inflammatory Macrophage Subtypes and Biomarkers in Periodontitis.

BACKGROUND: Periodontitis (PD) is a chronic inflammatory disease marked by immune dysregulation and ...

Takotsubo cardiomyopathy: Advances in pathophysiology, diagnostic biomarkers, genetic insights, multisystemic involvement, treatment updates & multidisciplinary interventions.

BACKGROUND: Takotsubo cardiomyopathy (TTC) is an acute, reversible cardiac syndrome triggered by phy...

Correction to: Kidney Week 2025 Abstract Artificial Intelligence in Autosomal Dominant Polycystic Kidney Disease: Transforming Diagnosis, Risk Stratification, and Therapeutic Interventions SA-PO0555.

Comprehensive multi-omics data to construct hepatocellular carcinoma pathway subtypes and classification model.

The high heterogeneity of Hepatocellular Carcinoma (HCC) severely hampers clinical outcomes. Current...

scMapNet: Marker-based cell type annotation of scRNA-seq data via vision transfer learning with tabular-to-image transformations.

INTRODUCTION: Identifying cell types is a key step in single-cell RNA sequencing data analysis that ...

CSF1R and macrophage infiltration: Integrated magnetic resonance imaging radiomics and deep learning-driven models for the preoperative assessment of glioma.

BACKGROUND: Colony-stimulating factor-1 receptor (CSF1R) signaling is crucial for the ability of tum...

Magnetic resonance imaging-based artificial intelligence model predicts neoadjuvant therapy response in triple-negative breast cancer.

PURPOSE: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited...

Ergonomic handheld chip: An instrument-free RPA-CRISPR platform for rapid home self-testing.

Global outbreaks of viral infectious diseases underscore the urgent need for low-cost, instrument-fr...

Engineering genetic elements for microbial protein expression systems: Advances, challenges, applications, and prospects.

The rising global demand for sustainable protein sources poses critical challenges across food, phar...

Utility of the PROSTest, a Novel Blood-Based Molecular Assay, Versus PSA for Prostate Cancer Stratification and Detection of Disease.

BACKGROUND: Prostate cancer (PCa) is the most common solid organ cancer in men and the fifth leading...