Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 295-315 of 11,038 articles
SENP1 mitigates intervertebral disc degeneration: mechanisms involving suppression of pyroptosis and apoptosis in nucleus pulposus cells.

BACKGROUND: Intervertebral disc degeneration (IDD) is a leading cause of global disability. This stu...

May 2026 42108475
A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits.

One significant advancement in synthetic biology is the development of synthetic gene circuits with ...

May 2026 42112575
Large language model assisted hyper-heuristic evolutionary algorithm for groundwater level prediction.

This paper proposes a novel Large Language Model (LLM)-assisted hyper-heuristic evolutionary algorit...

May 2026 42115303
Offspring genetic diversity regulates rearing experiences that predict differential susceptibility to Chd8 haploinsufficiency.

Loss-of-function mutations in the autism-associated CHD8 gene are highly penetrant for trait and beh...

May 2026 42115306
The evolving global landscape of first-in-class oncology drug innovation.

First-in-class (FIC) oncology drugs-defined by their novel mechanisms of action or targeting of prev...

May 2026 42115599
Identification of PTPRR gene associated with cirrhosis and sarcopenia based on bioinformatics and machine learning.

BACKGROUND: Cirrhosis and sarcopenia frequently coexist and are associated with poor clinical outcom...

May 2026 42115738
Using deep learning to identify inherited retinal diseases based on wide-field retinal imaging data.

OBJECTIVE: To evaluate a novel image-based deep learning method for the automated identification of ...

May 2026 42113772
Single-cell and bulk omics uncover fibroblast heterogeneity and HSPH1 as a key driver in Barrett's esophagus to esophageal adenocarcinoma progression.

BACKGROUND: Esophageal adenocarcinoma (EAC) is a highly aggressive malignancy with poor prognosis, o...

May 2026 42108450
Genomic variation drives plant flavor diversification.

Plant flavor diversity arises from genomic variation across species and cultivars, yet the mechanism...

May 2026 42108611
Precision theranostics in oncology: integrating antibody-drug conjugates, radioimmunotherapy, and immuno‑PET for adaptive cancer care.

The century-old vision of a "magic bullet" in oncology is being realized through the paradigm of pre...

May 2026 42107020
Artificial intelligence model predicts malignant transformation of oral leukoplakia and optimizes interventions.

PURPOSE: Oral leukoplakia (OL), the most common oral potentially malignant disorder (OPMD), poses a ...

May 2026 42107221
Single-cell profiling identifies a pro-tumoral VCAN positive macrophage subset and defines a prognostic signature in glioblastoma.

Glioblastoma (GBM), the most aggressive primary brain tumor, develops within a tumor microenvironmen...

May 2026 42105040
Protein Language Model Embeddings Improve HIV Drug Resistance Prediction: A Comprehensive Benchmark with Attention-Based Interpretability.

MOTIVATION: Accurate prediction of HIV drug resistance from viral sequences is critical for optimisi...

May 2026 42105210
Integration of transcriptome and DNA methylation reveals the mechanism of cilia-related genes in recurrent miscarriage.

Recurrent miscarriage (RM), a complex pregnancy disorder with largely undefined molecular mechanisms...

May 2026 42106497
Integrative analysis of single-cell and transcriptomic data with RT-qPCR validation explores TRPM4-associated gene signatures in osteoarthritis synovium.

Osteoarthritis (OA) is a chronic, disabling condition whose pathogenesis remains unclear. TRPM4 is c...

May 2026 42106542
Exploring the prognostic role of senescence-related genes in gastric cancer through multi-omics integration and machine learning.

Cellular senescence plays a context-dependent role in gastric cancer (GC), functioning both through ...

May 2026 42106891
Molecular basis of precision nutrition: Food components, microbiome-derived metabolites, and multi-omics modeling.

Metabolic disorders, including obesity, type 2 diabetes, metabolic syndrome, and fatty liver disease...

May 2026 42181960
In-depth exploration into the multifaceted regulatory mechanisms of carotenoid metabolism in microalgae.

Microalgae offer a sustainable and efficient way to produce natural carotenoids, with advantages suc...

May 2026 42107799
AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology.

Spatial transcriptomics (ST) assays are transforming our understanding of tumor heterogeneity, but t...

May 2026 42105763
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