Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Integrating machine learning and bioinformatics approaches to identify novel diagnostic gene biomarkers for diabetic mice.

Diabetes is a complex metabolic disorder, and its pathogenesis involves the interplay of genetic, en...

(1)
Jul 2025 40595011
Identification of exosome-related genes in NSCLC via integrated bioinformatics and machine learning analysis.

Exosomes are crucial in the development of non-small cell lung cancer (NSCLC), yet exosome-associate...

Jul 2025 40595797
Unveiling diagnostic biomarkers and therapeutic targets in lung adenocarcinoma using bioinformatics and experimental validation.

Lung adenocarcinoma (LUAD) is a major challenge in oncology due to its complex molecular structure a...

Jul 2025 40595823
A deep learning model for diagnosis of inherited retinal diseases.

To evaluate the performance of a multi-input deep learning (DL) model in detecting two common inheri...

Jul 2025 40595896
Gene therapy and genome editing for lipoprotein disorders.

Genetic factors play a critical role in the development of lipoprotein disorders, which significantl...

(1)
Jul 2025 40600248
Therapeutic horizons in metabolic dysfunction-associated steatohepatitis.

Metabolic dysfunction-associated steatohepatitis (MASH), the progressive inflammatory form of MASLD,...

Jul 2025 40590228
Regulation and induction of fungal secondary metabolites: a comprehensive review.

Fungal secondary metabolites (SMs) represent a vast reservoir of bioactive compounds with immense th...

(1)
Jul 2025 40590991
Identification of key biomarkers and potential therapeutic drugs in nasopharyngeal carcinoma based on comprehensive bioinformatics analysis.

Nasopharyngeal carcinoma (NPC) is the most prevalent type of head- and -neck cancer, and its diagnos...

Jul 2025 40591047
Machine learning reveals genes impacting oxidative stress resistance across yeasts.

Reactive oxygen species (ROS) are highly reactive molecules encountered by yeasts during routine met...

Jul 2025 40592811
Prognostic model of lung adenocarcinoma from the perspective of cancer-associated fibroblasts using single-cell and bulk RNA-sequencing.

Cancer-associated fibroblasts (CAFs) play important roles in the progression of lung adenocarcinoma ...

Jul 2025 40592920
Identification of pyroptosis related genes and subtypes in atherosclerosis using multiomic and single cell analysis.

Atherosclerosis (AS), the leading cause of cardiovascular diseases, is a chronic inflammatory disord...

Jul 2025 40592922
Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression.

Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-b...

(2)
Jul 2025 40593068
Deep generalizable prediction of RNA secondary structure via base pair motif energy.

Deep learning methods have demonstrated great performance for RNA secondary structure prediction. Ho...

Jul 2025 40593483
Data-driven protease engineering by DNA-recording and epistasis-aware machine learning.

Protein engineering has recently seen tremendous transformation due to machine learning (ML) tools t...

(1)
Jul 2025 40593579
Quantifying complexity in DNA structures with high resolution Atomic Force Microscopy.

DNA topology is essential for regulating cellular processes and maintaining genome stability, yet it...

(4)
Jul 2025 40593613
RiNALMo: general-purpose RNA language models can generalize well on structure prediction tasks.

While RNA has recently been recognized as an interesting small-molecule drug target, many challenges...

(1)
Jul 2025 40593636
Comprehensive datasets for RNA design, machine learning, and beyond.

RNA molecules are essential in regulating biological processes such as gene expression, cellular dif...

Jul 2025 40594473
Identifying ovarian cancer with machine learning DNA methylation pattern analysis.

The majority of patients with epithelial ovarian cancer (EOC) continue to be diagnosed at an advance...

Jul 2025 40594531
Deep learning-driven drug response prediction and mechanistic insights in cancer genomics.

In the field of cancer therapy, the diversity and heterogeneity of cancer genomes in clinical patien...

Jul 2025 40595000
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.

Clear cell renal cell carcinoma (ccRCC) represents a prevalent malignant kidney tumor characterized ...

Jul 2025 40595325
AI-enabled drug prediction and gene network analysis reveal therapeutic use of vorinostat for Rett Syndrome in preclinical models.

BACKGROUND: Many neurodevelopmental genetic disorders, such as Rett syndrome, are caused by a single...

Jul 2025 40595330
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