Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 3172-3192 of 11,662 articles
Machine learning-assisted decoding of temporal transcriptional dynamics via fluorescent timer.

Investigating the temporal dynamics of gene expression is crucial for understanding gene regulation ...

Jul 2025 40595611
Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy.

Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially r...

Jul 2025 40596187
Predict the degree of secondary structures of the encoding sequences in DNA storage by deep learning model.

DNA storage has been widely considered as a promising alternative for exponentially growing data. Ho...

Jul 2025 40596218
A transformer model for de novo sequencing of data-independent acquisition mass spectrometry data.

A core computational challenge in the analysis of mass spectrometry data is the de novo sequencing p...

(1)
Jul 2025 40596427
Leveraging autoencoder models and data augmentation to uncover transcriptomic diversity of gingival keratinocytes in single cell analysis.

Periodontitis, a chronic inflammatory condition of the periodontium, is associated with over 60 syst...

Jul 2025 40596529
Validation of an AI-enabled exome/transcriptome liquid biopsy platform for early detection, MRD, disease monitoring, and therapy selection for solid tumors.

Effective clinical management of patients with cancer requires highly accurate diagnosis, precise th...

Jul 2025 40596693
Ensemble machine learning-based pre-trained annotation approach for scRNA-seq data using gradient boosting with genetic optimizer.

Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of gene expression by allowing r...

Jul 2025 40596854
Can mutation abundance assess the biological behavior of BRAF-positive papillary thyroid carcinoma?

BACKGROUND: BRAF mutation is the most common genetic change in papillary thyroid carcinoma (PTC). Ne...

Jul 2025 40597144
Chimeric mis-annotations of genes remain pervasive in eukaryotic non-model organisms.

BACKGROUND: Accurate annotation of protein-coding genes is critical for genome analysis in non-model...

Jul 2025 40597599
Identification of potential biomarkers and mechanisms for keloid disorder based on comprehensive bioinformatics analysis and machine learning algorithms.

BACKGROUND: Keloid disorder (KD) encompasses a spectrum of fibroproliferative dermal conditions, the...

(2)
Jul 2025 40598145
Transforming heart transplantation care with multi-omics insights.

Heart transplantation (HTx) remains the definitive treatment for patients with end-stage heart disea...

Jul 2025 40598485
MRI's evolving role in rectal cancer in the era of personalized medicine.

Recent decades have seen great advances in the diagnosis and management of rectal cancer, and magnet...

Jun 2025 40586896
Environmental Drivers of Genetic Divergence in Two Corals From the Florida Keys.

Increasingly frequent marine heatwaves devastate coral reefs around the world, so there is great int...

(2)
Jun 2025 40589611
Genetic Deconvolution of Embryonic and Maternal Cell-Free DNA in Spent Culture Medium of Human Preimplantation Embryo Through Deep Learning.

Noninvasive preimplantation genetic testing for aneuploidy based on embryonic cell-free DNA (cfDNA) ...

Jun 2025 40583136
DNA methylation as a diagnostic biomarker for rheumatoid arthritis: a validation study using targeted sequencing.

OBJECTIVES: To validate the potential of the serotonin receptor encoded by 5-hydroxytryptamine recep...

(3)
Jun 2025 40576051
Generating and characterizing human telencephalic brain organoids from stem cell-derived single neural rosettes.

We have developed a method for generating human telencephalic organoids from stem cell-derived isola...

Jun 2025 40579542
Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA-A0201.

Class Ι major histocompatibility complexes (MHC-Ι), encoded by the highly polymorphic HLA-A, HLA-B, ...

Jun 2025 40577315
AffiGrapher: Contrastive Heterogeneous Graph Learning with Aromatic Virtual Nodes for RNA-Small Molecule Binding Affinity Prediction.

RNA molecules exhibit diverse structures and functions, making them promising drug targets. However,...

Jun 2025 40568757
Aptamer-directed siRNA delivery systems for triple-negative breast cancer therapy.

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by the ...

Jun 2025 40568899
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