Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 3256-3276 of 11,092 articles
OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion.

Epithelial ion and fluid transport studies in patient-derived organoids (PDOs) are increasingly bein...

Mar 2024 38480810
Deepm6A-MT: A deep learning-based method for identifying RNA N6-methyladenosine sites in multiple tissues.

N6-methyladenosine (m6A) is the most prevalent, abundant, and conserved internal modification in the...

Mar 2024 38485031
Identification of Genomic Signatures for Colorectal Cancer Survival Using Exploratory Data Mining.

Clinicopathological presentations are critical for establishing a postoperative treatment regimen in...

Mar 2024 38542194
Modular Spiking Neural Membrane Systems for Image Classification.

A variant of membrane computing models called Spiking Neural P systems (SNP systems) closely mimics ...

Mar 2024 38453666
DeePNAP: A Deep Learning Method to Predict Protein-Nucleic Acid Binding Affinity from Their Sequences.

Predicting the protein-nucleic acid (PNA) binding affinity solely from their sequences is of paramou...

Mar 2024 38458968
scFSNN: a feature selection method based on neural network for single-cell RNA-seq data.

While single-cell RNA sequencing (scRNA-seq) allows researchers to analyze gene expression in indivi...

Mar 2024 38459442
Artificial intelligence measured 3D body composition to predict pathological response in rectal cancer patients.

BACKGROUND: The treatment of locally advanced rectal cancer (LARC) is moving towards total neoadjuva...

Mar 2024 38456517
Machine learning to predict continuous protein properties from binary cell sorting data and map unseen sequence space.

Proteins are a diverse class of biomolecules responsible for wide-ranging cellular functions, from c...

Mar 2024 38451939
Integration of graph neural networks and genome-scale metabolic models for predicting gene essentiality.

Genome-scale metabolic models are powerful tools for understanding cellular physiology. Flux balance...

Mar 2024 38448436
A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors.

Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6is) have revolutionized breast cancer therapy. How...

Mar 2024 38443662
An Improved Clinical and Genetics-Based Prediction Model for Diabetic Foot Ulcer Healing.

The goal of this investigation was to use comprehensive prediction modeling tools and available gen...

Mar 2024 38258807
BiPSTP: Sequence feature encoding method for identifying different RNA modifications with bidirectional position-specific trinucleotides propensities.

RNA modification, a posttranscriptional regulatory mechanism, significantly influences RNA biogenesi...

Mar 2024 38447795
Enhancing Generalizability in Protein-Ligand Binding Affinity Prediction with Multimodal Contrastive Learning.

Improving the generalization ability of scoring functions remains a major challenge in protein-ligan...

Mar 2024 38441880
bioactivities and enzyme interactions of abietatrien-3-ol by bio-guided isolation from subsp. .

Abietatrien-3-ol (ATO) was isolated from the aerial part of the subsp. methanol-chloroform extract...

Mar 2024 40094939
Development of a deep learning model to distinguish the cause of optic disc atrophy using retinal fundus photography.

The differential diagnosis for optic atrophy can be challenging and requires expensive, time-consumi...

Mar 2024 38429319
Interpretable Multi-Scale Deep Learning for RNA Methylation Analysis across Multiple Species.

RNA modification plays a crucial role in cellular regulation. However, traditional high-throughput s...

Mar 2024 38474116
Identification and segregation of genes with improved recurrent neural network trained with optimal gene level and mutation level features.

Even though many different approaches have been employed to address the complex mutational heterogen...

Feb 2024 38424698
GANSamples-ac4C: Enhancing ac4C site prediction via generative adversarial networks and transfer learning.

RNA modification, N4-acetylcytidine (ac4C), is enzymatically catalyzed by N-acetyltransferase 10 (NA...

Feb 2024 38431142
Comparing robotic and manual injection methods in zebrafish embryos for high-throughput RNA silencing using CRISPR-RfxCas13d.

In this study, the authors compared the efficiency of automated robotic and manual injection methods...

Feb 2024 38420933
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