Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 3340-3360 of 11,662 articles
Extrachromosomal circular DNA drives dynamic genome plasticity: emerging roles in disease progression and clinical potential.

Extrachromosomal circular DNA (eccDNA) has emerged as a dynamic and versatile genomic element with k...

May 2025 40521196
deepTFBS: Improving within- and Cross-Species Prediction of Transcription Factor Binding Using Deep Multi-Task and Transfer Learning.

The precise prediction of transcription factor binding sites (TFBSs) is crucial in understanding gen...

May 2025 40411397
Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome.

Despite a significant burden of neurobehavioral and psychiatric comorbidities in children with Down ...

May 2025 40413309
Role of machine learning in molecular pathology for breast cancer: A review on gene expression profiling and RNA sequencing application.

INTRODUCTION: Breast cancer is the most prevalent cancer among women, with growing incidence and mor...

May 2025 40419230
Role of artificial intelligence in cancer drug discovery and development.

The role of artificial intelligence (AI) in cancer drug discovery and development has garnered signi...

May 2025 40414522
Extended Linear Confined Zipper Cascaded Reaction for Highly Efficient Intracellular Imaging and Assisting Diagnosis of Thyroid Cancer.

Highly sensitive detection and in situ tracing analysis of small-molecule biomarkers are particularl...

May 2025 40405610
Construction and Multi-dimensional Validation of a Lactylation-Related Signature for Glioblastoma Multiforme Prognostic and Therapeutic Purposes.

Glioblastoma multiforme, one of the most malignant types of brain tumor, heavily relies on glycolyti...

May 2025 40407859
Mechanisms underlying obesity-malignancy connection: a systematic narrative review.

The association between obesity and cancer risk carries substantial public health ramifications as o...

(1)
May 2025 40408050
Single-cell multimodal analysis reveals tumor microenvironment predictive of treatment response in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) constitutes over 80% of lung cancer cases and remains a leading c...

May 2025 40408481
Biallelic loss-of-function variants in ZNF142 are associated with a robust DNA methylation signature affecting a limited number of genomic loci.

Biallelic inactivating variants in ZNF142 underlie a clinically variable neurodevelopmental disorder...

May 2025 40410387
A standardized framework for robust fragmentomic feature extraction from cell-free DNA sequencing data.

Fragmentomics features of cell-free DNA represent promising non-invasive biomarkers for cancer diagn...

May 2025 40410787
Integrating Knowledge: The Power of Ontologies in Psychiatric Research and Clinical Informatics.

Ontologies are structured frameworks for representing knowledge by systematically defining concepts,...

May 2025 40414449
Towards precision medicine in antiphospholipid syndrome.

Antiphospholipid syndrome is a rare systemic autoimmune disorder with complex pathophysiology and hi...

(4)
May 2025 40418947
Machine-guided dual-objective protein engineering for deimmunization and therapeutic functions.

Cell and gene therapies often express nonhuman proteins, which carry a risk of anti-therapy immunoge...

May 2025 40466641
Analysing protein complexes in plant science: insights and limitation with AlphaFold 3.

AlphaFold 3 (AF3), an artificial intelligence (AI)-based software for protein complex structure pred...

May 2025 40402396
Identification of shared mechanisms between Alzheimer's disease and atherosclerosis by integrated bioinformatics analysis.

Alzheimer's disease (AD) and atherosclerosis (AS) are two interacting diseases mostly affecting aged...

May 2025 40405226
Identification of m5C RNA modification-related gene signature for predicting prognosis and immune microenvironment-related characteristics of heart failure.

BACKGROUND: Methylation of RNA is involved in many pathophysiological processes. The roles of N6-met...

May 2025 40405297
Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer.

Metastasis remains the leading cause of cancer-related mortality, yet predicting future metastasis i...

May 2025 40475399
Explainable AI Model Reveals Informative Mutational Signatures for Cancer-Type Classification.

: The prediction of cancer types is primarily reliant on driver genes and their specific mutations. ...

(1)
May 2025 40507213
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