Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 3613-3633 of 11,104 articles
Deep learning-based prediction of H3K27M alteration in diffuse midline gliomas based on whole-brain MRI.

BACKGROUND: H3K27M mutation status significantly affects the prognosis of patients with diffuse midl...

Jul 2023 37461358
Rational design of functional amyloid fibrillar assemblies.

Amyloid fibrillar assemblies, originally identified as pathological entities in neurodegenerative di...

Jul 2023 37341718
Systematical analysis of underlying markers associated with Marfan syndrome via integrated bioinformatics and machine learning strategies.

Marfan syndrome (MFS) is a hereditary disease with high mortality. This study aimed to explore perip...

Jul 2023 37449753
CRISPR-Cas-Based Biomonitoring for Marine Environments: Toward CRISPR RNA Design Optimization Via Deep Learning.

Almost all of Earth's oceans are now impacted by multiple anthropogenic stressors, including the spr...

Jul 2023 37439822
Multi-batch single-cell comparative atlas construction by deep learning disentanglement.

Cell state atlases constructed through single-cell RNA-seq and ATAC-seq analysis are powerful tools ...

Jul 2023 37433791
The deep arbitrary polynomial chaos neural network or how Deep Artificial Neural Networks could benefit from data-driven homogeneous chaos theory.

Artificial Intelligence and Machine learning have been widely used in various fields of mathematical...

Jul 2023 37480771
Rm-LR: A long-range-based deep learning model for predicting multiple types of RNA modifications.

Recent research has highlighted the pivotal role of RNA post-transcriptional modifications in the re...

Jul 2023 37515874
HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence.

RNA-binding proteins (RBPs) control RNA metabolism to orchestrate gene expression and, when dysfunct...

Jul 2023 37421941
Explainable multi-task learning improves the parallel estimation of polygenic risk scores for many diseases through shared genetic basis.

Many complex diseases share common genetic determinants and are comorbid in a population. We hypothe...

Jul 2023 37418352
A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's disease risk and rates of disease progression.

BACKGROUND: Identifying genetic patterns that contribute to Alzheimer's disease (AD) is important no...

Jul 2023 37409680
Harnessing the power of artificial intelligence to advance cell therapy.

Cell therapies are powerful technologies in which human cells are reprogrammed for therapeutic appli...

Jul 2023 37415280
A hierarchical self-attention-guided deep learning framework to predict breast cancer response to chemotherapy using pre-treatment tumor biopsies.

BACKGROUND: Pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) has demonstrated ...

Jul 2023 37403567
High accuracy epidermal growth factor receptor mutation prediction via histopathological deep learning.

BACKGROUND: The detection of epidermal growth factor receptor (EGFR) mutations in patients with non-...

Jul 2023 37407963
Prediction of on-target and off-target activity of CRISPR-Cas13d guide RNAs using deep learning.

Transcriptome engineering applications in living cells with RNA-targeting CRISPR effectors depend on...

Jul 2023 37400521
Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.

Plasma cell-free DNA (cfDNA) is a noninvasive biomarker for cell death of all organs. Deciphering th...

Jul 2023 37399400
Deep learning applications in single-cell genomics and transcriptomics data analysis.

Traditional bulk sequencing methods are limited to measuring the average signal in a group of cells,...

Jul 2023 37393865
Sampling effect in predicting the evolutionary response of populations to climate change.

Genomic data and machine learning approaches have gained interest due to their potential to identify...

Jun 2023 37392001
GR-m6A: Prediction of N6-methyladenosine sites in mammals with molecular graph and residual network.

RNA N6-methyladenine (m6A), which is produced by the methylation of the N6 position of eukaryotic ad...

Jun 2023 37450964
Amelogenesis imperfecta. case report.

The main origin of amelogenesis imperfecta (AI) is a genetic alteration inherited by a family member...

Jun 2023 38288452
Gene-specific machine learning for pathogenicity prediction of rare BRCA1 and BRCA2 missense variants.

Machine learning-based pathogenicity prediction helps interpret rare missense variants of BRCA1 and ...

Jun 2023 37380723
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