Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Semantic segmentation of human cell nucleus using deep U-Net and other versions of U-Net models.

The deep learning models play an essential role in many areas, including medical image analysis. The...

Jul 2022 35822269
A hybrid metaheuristic-deep learning technique for the pan-classification of cancer based on DNA methylation.

BACKGROUND: DNA Methylation is one of the most important epigenetic processes that are crucial to re...

Jul 2022 35818034
Genetics and Epigenetics in Personalized Nutrition: Evidence, Expectations, and Experiences.

With the presentation of the blueprint of the first human genome in 2001 and the advent of technolog...

Jul 2022 35770348
A web server for identifying circRNA-RBP variable-length binding sites based on stacked generalization ensemble deep learning network.

Circular RNA (circRNA) can exert biological functions by interacting with RNA-binding protein (RBP),...

Jul 2022 35810958
Gene function prediction in five model eukaryotes exclusively based on gene relative location through machine learning.

The function of most genes is unknown. The best results in automated function prediction are obtaine...

Jul 2022 35803984
Exploring the Chinese Public's Perception of Omicron Variants on Social Media: LDA-Based Topic Modeling and Sentiment Analysis.

The COVID-19 pandemic caused by SARS-CoV-2 is still raging. Similar to other RNA viruses, SARS-COV-2...

Jul 2022 35886225
Applications of artificial intelligence multiomics in precision oncology.

Cancer is the second leading worldwide disease that depends on oncogenic mutations and non-mutated g...

Jul 2022 35796775
Predicting RNA solvent accessibility from multi-scale context feature via multi-shot neural network.

Knowledge of RNA solvent accessibility has recently become attractive due to the increasing awarenes...

Jul 2022 35809650
Inverse folding based pre-training for the reliable identification of intrinsic transcription terminators.

It is well-established that neural networks can predict or identify structural motifs of non-coding ...

Jul 2022 35797361
Histopathologic Basis for a Chest CT Deep Learning Survival Prediction Model in Patients with Lung Adenocarcinoma.

Background A preoperative CT-based deep learning (DL) prediction model was proposed to estimate dise...

Jul 2022 35787198
DNA: Deeply Supervised Nonlinear Aggregation for Salient Object Detection.

Recent progress on salient object detection mainly aims at exploiting how to effectively integrate m...

Jul 2022 33531332
Deep learning-based microarray cancer classification and ensemble gene selection approach.

Malignancies and diseases of various genetic origins can be diagnosed and classified with microarray...

Jul 2022 35790076
Single-cell specific and interpretable machine learning models for sparse scChIP-seq data imputation.

MOTIVATION: Single-cell Chromatin ImmunoPrecipitation DNA-Sequencing (scChIP-seq) analysis is challe...

Jul 2022 35776722
A Deep Learning Approach for Automated Segmentation of Kidneys and Exophytic Cysts in Individuals with Autosomal Dominant Polycystic Kidney Disease.

BACKGROUND: Total kidney volume (TKV) is an important imaging biomarker in autosomal dominant polycy...

Jun 2022 35768178
Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression.

Currently, psychiatric diagnoses are, in contrast to most other medical fields, based on subjective ...

Jun 2022 35767618
Hyb4mC: a hybrid DNA2vec-based model for DNA N4-methylcytosine sites prediction.

BACKGROUND: DNA N4-methylcytosine is part of the restrictive modification system, which works by reg...

Jun 2022 35768759
DeepPN: a deep parallel neural network based on convolutional neural network and graph convolutional network for predicting RNA-protein binding sites.

BACKGROUND: Addressing the laborious nature of traditional biological experiments by using an effici...

Jun 2022 35768792
Development and Application of Two Inducible Expression Systems for Streptococcus suis.

Streptococcus suis is an important zoonotic bacterial pathogen posing a threat to the pig industry a...

Jun 2022 35758678
Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer.

NIMA-related kinase7 (NEK7) plays a multifunctional role in cell division and NLRP3 inflammasone act...

Jun 2022 35807344
A new deep learning technique reveals the exclusive functional contributions of individual cancer mutations.

Cancers are caused by genomic alterations that may be inherited, induced by environmental carcinogen...

Jun 2022 35753349
Clinical actionability of triaging DNA mismatch repair deficient colorectal cancer from biopsy samples using deep learning.

BACKGROUND: We aimed to develop a deep learning (DL) model to predict DNA mismatch repair (MMR) stat...

Jun 2022 35753152
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