Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Achieving robust somatic mutation detection with deep learning models derived from reference data sets of a cancer sample.

BACKGROUND: Accurate detection of somatic mutations is challenging but critical in understanding can...

Jan 2022 34996510
Discovering cell types using manifold learning and enhanced visualization of single-cell RNA-Seq data.

Identifying relevant disease modules such as target cell types is a significant step for studying di...

Jan 2022 34996927
Advanced Deep Learning Human Herpes Virus 6 (HHV-6) Molecular Detection in Understanding Human Infertility.

To see if HHV-6 may be a cause of infertility, researchers looked at 18 men and 10 women who had une...

Jan 2022 35035452
Deep-Learning-Based Cancer Profiles Classification Using Gene Expression Data Profile.

The quantity of data required to give a valid analysis grows exponentially as machine learning dimen...

Jan 2022 35035840
PanClassif: Improving pan cancer classification of single cell RNA-seq gene expression data using machine learning.

Cancer is one of the major causes of human death per year. In recent years, cancer identification an...

Jan 2022 34998929
DEGnext: classification of differentially expressed genes from RNA-seq data using a convolutional neural network with transfer learning.

BACKGROUND: A limitation of traditional differential expression analysis on small datasets involves ...

Jan 2022 34991439
Deep Unfolding for Non-Negative Matrix Factorization with Application to Mutational Signature Analysis.

Non-negative matrix factorization (NMF) is a fundamental matrix decomposition technique that is used...

Jan 2022 34986029
OperonSEQer: A set of machine-learning algorithms with threshold voting for detection of operon pairs using short-read RNA-sequencing data.

Operon prediction in prokaryotes is critical not only for understanding the regulation of endogenous...

Jan 2022 34986143
Deep RED Unfolding Network for Image Restoration.

The deep unfolding network (DUN) provides an efficient framework for image restoration. It consists ...

Jan 2022 34951845
An RNA-based theory of natural universal computation.

Life is confronted with computation problems in a variety of domains including animal behavior, sing...

Dec 2021 34979104
RegVar: Tissue-specific Prioritization of Non-coding Regulatory Variants.

Non-coding genomic variants constitute the majority of trait-associated genome variations; however, ...

Dec 2021 34973416
Tungsten oxide polymorphs and their multifunctional applications.

Owing to the natural abundance, easy availability, high stability, non-stoichiometry, and chemical d...

Dec 2021 34990910
Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework.

Invasive rodent populations pose a threat to biodiversity across the globe. When confronted with the...

Dec 2021 34965253
DNA-based artificial dendritic cells for in situ cytotoxic T cell stimulation and immunotherapy.

In immunotherapy, ex vivo stimulation of T cells requires significant resources and effort. Here, we...

Dec 2021 35386353
DiversityScanner: Robotic handling of small invertebrates with machine learning methods.

Invertebrate biodiversity remains poorly understood although it comprises much of the terrestrial an...

Dec 2021 34863029
NoAS-DS: Neural optimal architecture search for detection of diverse DNA signals.

Neural network architectures are high-performing variable models that can solve many learning tasks....

Dec 2021 34979461
Manipulation of Multiple Cell-Cell Interactions by Tunable DNA Scaffold Networks.

Manipulation of cell-cell interactions via cell surface engineering has potential biomedical applica...

Dec 2021 34873818
NGS read classification using AI.

Clinical metagenomics is a powerful diagnostic tool, as it offers an open view into all DNA in a pat...

Dec 2021 34936673
Combination of liquid crystal and deep learning reveals distinct signatures of Parkinson's disease-related wild-type α-synuclein and six pathogenic mutants.

α-Synuclein is a central player in Parkinson's disease (PD) pathology. Various point mutations in α-...

Dec 2021 34877798
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