Genetics

Machine Learning Approaches for the Prioritization of Genomic Variants Impacting Pre-mRNA Splicing.

Defects in pre-mRNA splicing are frequently a cause of Mendelian disease. Despite the advent of next...

Point-of-care cervical cancer screening using deep learning-based microholography.

Most deaths (80%) from cervical cancer occur in regions lacking adequate screening infrastructures o...

DualWMDR: Detecting epistatic interaction with dual screening and multifactor dimensionality reduction.

Detecting epistatic interaction is a typical way of identifying the genetic susceptibility of comple...

Deep Learning Deciphers Protein-RNA Interaction.

ImaGene: a convolutional neural network to quantify natural selection from genomic data.

BACKGROUND: The genetic bases of many complex phenotypes are still largely unknown, mostly due to th...

A 21‑gene Support Vector Machine classifier and a 10‑gene risk score system constructed for patients with gastric cancer.

Gastric cancer (GC) ranks fifth in terms of incidence and third in terms of tumor mortality worldwid...

The Hearing Impairment Ontology: A Tool for Unifying Hearing Impairment Knowledge to Enhance Collaborative Research.

Hearing impairment (HI) is a common sensory disorder that is defined as the partial or complete inab...

Unsupervised feature selection algorithm for multiclass cancer classification of gene expression RNA-Seq data.

This paper presents a Grouping Genetic Algorithm (GGA) to solve a maximally diverse grouping problem...

Artificial intelligence in genetic services delivery: Utopia or apocalypse?

Artificial intelligence (AI) technologies have a long history, with increasing presence and potentia...

The complete chloroplast genome of , an important tropical crop.

(Willd. ex Spreng.) K. Schum., an economically important tree in the family Malvaceae, is native to...

Ranking of non-coding pathogenic variants and putative essential regions of the human genome.

A gene is considered essential if loss of function results in loss of viability, fitness or in disea...

Artificial intelligence in clinical and genomic diagnostics.

Artificial intelligence (AI) is the development of computer systems that are able to perform tasks t...

AGONOTES: A Robot Annotator for Argonaute Proteins.

The argonaute protein (Ago) exists in almost all organisms. In eukaryotes, it functions as a regulat...

Machine learning-based quantitative texture analysis of conventional MRI combined with ADC maps for assessment of IDH1 mutation in high-grade gliomas.

PURPOSE: To assess the performance of texture analysis of conventional magnetic resonance imaging (M...

Characterization of the complete chloroplast genome of sunflower family species (Compositae).

is a perennial medicinal plant belong the sunflower family Compositae, which is widely distributed ...

Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

Genome Wide Association Studies (GWAS) have evaluated several genes related to vitamin D synthesis,...

A genetic programming-based approach to identify potential inhibitors of serine protease of .

We applied genetic programming approaches to understand the impact of descriptors on inhibitory eff...

CPEM: Accurate cancer type classification based on somatic alterations using an ensemble of a random forest and a deep neural network.

With recent advances in DNA sequencing technologies, fast acquisition of large-scale genomic data ha...

Gene expression based survival prediction for cancer patients-A topic modeling approach.

Cancer is one of the leading cause of death, worldwide. Many believe that genomic data will enable u...

WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans.

Caenorhabditis elegans is a popular organism for aging research owing to its highly conserved molecu...

An improved deep learning method for predicting DNA-binding proteins based on contextual features in amino acid sequences.

As the number of known proteins has expanded, how to accurately identify DNA binding proteins has be...