Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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The key role of inoculated sludge in fast start-up of sequencing batch reactor for the domestication of aerobic granular sludge.

Two types of inoculated sludges, granular sludge that had been stored at -20°C and activated sludge,...

BERMP: a cross-species classifier for predicting mA sites by integrating a deep learning algorithm and a random forest approach.

N-methyladenosine (mA) is a prevalent RNA methylation modification involved in several biological pr...

DES-Mutation: System for Exploring Links of Mutations and Diseases.

During cellular division DNA replicates and this process is the basis for passing genetic informatio...

RNA-seq analysis reveals different gene ontologies and pathways in rheumatoid arthritis and Kashin-Beck disease.

AIMS: To understand the pathogenesis of cartilage damage in Kashin-Beck disease (KBD) and rheumatoid...

Utilizing Deep Learning and Genome Wide Association Studies for Epistatic-Driven Preterm Birth Classification in African-American Women.

Genome-Wide Association Studies (GWAS) are used to identify statistically significant genetic varian...

Machine learning identifies interacting genetic variants contributing to breast cancer risk: A case study in Finnish cases and controls.

We propose an effective machine learning approach to identify group of interacting single nucleotide...

Novel symmetry-based gene-gene dissimilarity measures utilizing Gene Ontology: Application in gene clustering.

In recent years DNA microarray technology, leading to the generation of high-volume biological data,...

Can Deep Learning Improve Genomic Prediction of Complex Human Traits?

The genetic analysis of complex traits does not escape the current excitement around artificial inte...

An Efficient Feature Selection Strategy Based on Multiple Support Vector Machine Technology with Gene Expression Data.

The application of gene expression data to the diagnosis and classification of cancer has become a h...

Controlling Complexity of Cerebral Cortex Simulations-I: CxSystem, a Flexible Cortical Simulation Framework.

Simulation of the cerebral cortex requires a combination of extensive domain-specific knowledge and ...

Management practices associated with strongylid parasite prevalence on horse farms in rural counties of Kentucky.

Anthelmintic resistance among cyathostomin parasites is a wide-spread problem. The parasite control ...

Sequential Integration of Fuzzy Clustering and Expectation Maximization for Transcription Factor Binding Site Identification.

The identification of transcription factor binding sites (TFBSs) is a problem for which computationa...

Identification of synthetic lethality based on a functional network by using machine learning algorithms.

Synthetic lethality is the synthesis of mutations leading to cell death. Tumor-specific synthetic le...

Rise of Deep Learning for Genomic, Proteomic, and Metabolomic Data Integration in Precision Medicine.

Machine learning (ML) is being ubiquitously incorporated into everyday products such as Internet sea...

Conclusion: harmonisation in genomic and health data sharing for research: an impossible dream?

There are clear benefits from genomics and health data sharing in research and in therapy for indivi...

iRNA-2OM: A Sequence-Based Predictor for Identifying 2'-O-Methylation Sites in Homo sapiens.

2'-O-methylation plays an important biological role in gene expression. Owing to the explosive incre...

Integration of Gene Expression Profile Data to Screen and Verify Hub Genes Involved in Osteoarthritis.

Osteoarthritis (OA) is one of the most common diseases worldwide, but the pathogenic genes and pathw...

Identifying epidermal growth factor receptor mutation status in patients with lung adenocarcinoma by three-dimensional convolutional neural networks.

OBJECTIVE:: Genetic phenotype plays a central role in making treatment decisions of lung adenocarcin...

KELM-CPPpred: Kernel Extreme Learning Machine Based Prediction Model for Cell-Penetrating Peptides.

Cell-penetrating peptides (CPPs) facilitate the transport of pharmacologically active molecules, suc...

Cancer type prediction based on copy number aberration and chromatin 3D structure with convolutional neural networks.

BACKGROUND: With the developments of DNA sequencing technology, large amounts of sequencing data hav...

Establishment of a SVM classifier to predict recurrence of ovarian cancer.

Gene expression data using retrieved ovarian cancer (OC) samples were used to identify genes of inte...

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