Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 4999-5019 of 11,138 articles
A Support Vector Machine Model Predicting the Risk of Duodenal Cancer in Patients with Familial Adenomatous Polyposis at the Transcript Levels.

OBJECTIVE: Familial adenomatous polyposis (FAP) is one major type of inherited duodenal cancer. The ...

Jun 2020 32626748
Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action.

Bipolar disorder (BD) is a major healthcare and socio-economic challenge. Despite its substantial bu...

Jun 2020 32536571
Differentiating molecular etiologies of Angelman syndrome through facial phenotyping using deep learning.

Angelman syndrome (AS) is caused by several genetic mechanisms that impair the expression of materna...

Jun 2020 32524756
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding.

DNA-encoded small molecule libraries (DELs) have enabled discovery of novel inhibitors for many dist...

Jun 2020 32525674
Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network.

Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in ca...

Jun 2020 32528130
A network-based computational framework to predict and differentiate functions for gene isoforms using exon-level expression data.

MOTIVATION: Alternative splicing makes significant contributions to functional diversity of transcri...

Jun 2020 32534132
Application of Whole-Genome Sequences and Machine Learning in Source Attribution of Salmonella Typhimurium.

Prevention of the emergence and spread of foodborne diseases is an important prerequisite for the im...

Jun 2020 32515055
Predicting geographic location from genetic variation with deep neural networks.

Most organisms are more closely related to nearby than distant members of their species, creating sp...

Jun 2020 32511092
Acute myeloid leukemia and artificial intelligence, algorithms and new scores.

Artificial intelligence, and more narrowly machine-learning, is beginning to expand humanity's capac...

Jun 2020 33038981
Matrix factorization with neural network for predicting circRNA-RBP interactions.

BACKGROUND: Circular RNA (circRNA) has been extensively identified in cells and tissues, and plays c...

Jun 2020 32503474
Homogeneous DNA-only keypad locks enable one-pot assay of multi-inputs.

Homogeneous DNA-only keypad locks were built with multi-stranded scalable junction substrates and a ...

Jun 2020 32490866
Effects of CYP2C19*17 Genetic Polymorphisms on the Steady-State Concentration of Diazepam in Patients With Alcohol Withdrawal Syndrome.

Diazepam is one of the most widely prescribed tranquilizers for the therapy of alcohol withdrawal s...

Jun 2020 34720165
Using Reactome to build an autophagy mechanism knowledgebase.

The 21st century has revealed much about the fundamental cellular process of autophagy. Autophagy co...

Jun 2020 32486891
Prediction of N6-methyladenosine sites using convolution neural network model based on distributed feature representations.

N-methyladenosine (mA) is a well-studied and most common interior messenger RNA (mRNA) modification ...

Jun 2020 32593932
Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov.

A novel coronavirus, called 2019-nCoV, was recently found in Wuhan, Hubei Province of China, and now...

Jun 2020 32488835
Powerful, transferable representations for molecules through intelligent task selection in deep multitask networks.

Chemical representations derived from deep learning are emerging as a powerful tool in areas such as...

Jun 2020 32478374
Machine learning uncovers cell identity regulator by histone code.

Conversion between cell types, e.g., by induced expression of master transcription factors, holds gr...

Jun 2020 32483223
CRISPRpred(SEQ): a sequence-based method for sgRNA on target activity prediction using traditional machine learning.

BACKGROUND: The latest works on CRISPR genome editing tools mainly employs deep learning techniques....

Jun 2020 32487025
Predicting RNA SHAPE scores with deep learning.

Secondary structure prediction approaches rely typically on models of equilibrium free energies that...

May 2020 32476596
Beyond the limitation of targeted therapy: Improve the application of targeted drugs combining genomic data with machine learning.

Precision oncology involves effectively selecting drugs for cancer patients and planning an effectiv...

May 2020 32473309
A machine learning model that classifies breast cancer pathologic complete response on MRI post-neoadjuvant chemotherapy.

BACKGROUND: For breast cancer patients undergoing neoadjuvant chemotherapy (NAC), pathologic complet...

May 2020 32466777
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