Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Identification of genes of four malignant tumors and a novel prediction model development based on PPI data and support vector machines.

Triple-negative breast cancer (TNBC), colon adenocarcinoma (COAD), ovarian cancer (OV), and glioblas...

Oct 2019 31645679
An evaluation of machine-learning for predicting phenotype: studies in yeast, rice, and wheat.

In phenotype prediction the physical characteristics of an organism are predicted from knowledge of ...

Oct 2019 32174648
Machine learning and bioinformatics models to identify gene expression patterns of ovarian cancer associated with disease progression and mortality.

Ovarian cancer (OC) is a common cause of cancer death among women worldwide, so there is a pressing ...

Oct 2019 31655274
for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation.

Spatiotemporal regulation of molecular activities dictates cellular function and fate. Investigation...

Oct 2019 33163483
Clinical Significance of Circulating Cardiomyocyte-Specific Cell-Free DNA in Patients With Heart Failure: A Proof-of-Concept Study.

We investigated clinical significance of cell-free DNA (cfDNA) in heart failure. This study enrolled...

Oct 2019 32001048
A deep learning ensemble for function prediction of hypothetical proteins from pathogenic bacterial species.

Protein function prediction is a crucial task in the post-genomics era due to their diverse irreplac...

Oct 2019 31698160
Joint Ranking SVM and Binary Relevance with robust Low-rank learning for multi-label classification.

Multi-label classification studies the task where each example belongs to multiple labels simultaneo...

Oct 2019 31675625
DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data.

Single-cell RNA sequencing (scRNA-seq) offers new opportunities to study gene expression of tens of ...

Oct 2019 31627739
Foam Sclerotherapy for Cyst Volume Reduction in Autosomal Dominant Polycystic Kidney Disease: A Prospective Cohort Study.

RATIONALE & OBJECTIVE: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inher...

Oct 2019 32734217
cytogenotoxic evaluation of sertraline.

Sertraline (SRT) is an antidepressant agent used as a neuronal selective serotonin-reuptake inhibito...

Oct 2019 31736631
D-GPM: A Deep Learning Method for Gene Promoter Methylation Inference.

Whole-genome bisulfite sequencing generates a comprehensive profiling of the gene methylation levels...

Oct 2019 31615113
Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates.

Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) have promisi...

Oct 2019 31604961
Analyzing Tumor Gene Expression Factors with the CorExplorer Web Portal.

Differential gene expression analysis is an important technique for understanding disease states. Th...

Oct 2019 31657800
LightGBM: An Effective and Scalable Algorithm for Prediction of Chemical Toxicity-Application to the Tox21 and Mutagenicity Data Sets.

Machine learning algorithms have attained widespread use in assessing the potential toxicities of ph...

Oct 2019 31560206
Uncovering Thousands of New Peptides with Sequence-Mask-Search Hybrid Peptide Sequencing Framework.

Typical analyses of mass spectrometry data only identify amino acid sequences that exist in referenc...

Oct 2019 31591261
QTG-Finder: A Machine-Learning Based Algorithm To Prioritize Causal Genes of Quantitative Trait Loci in Arabidopsis and Rice.

Linkage mapping is one of the most commonly used methods to identify genetic loci that determine a t...

Oct 2019 31358562
Pathway-Based Single-Cell RNA-Seq Classification, Clustering, and Construction of Gene-Gene Interactions Networks Using Random Forests.

Single-cell RNA-Sequencing (scRNA-Seq), an advanced sequencing technique, enables biomedical researc...

Oct 2019 31581101
One-shot optimization of multiple enzyme parameters: Tailoring glucose oxidase for pH and electron mediators.

Enzymes are biological catalysts with many industrial applications, but natural enzymes are usually ...

Oct 2019 31520472
LOTUS: A single- and multitask machine learning algorithm for the prediction of cancer driver genes.

Cancer driver genes, i.e., oncogenes and tumor suppressor genes, are involved in the acquisition of ...

Sep 2019 31568528
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