Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 631-651 of 11,636 articles
Kidney-specific deletion of the BicC family RNA-binding protein 1 triggers an ADPKD-like cystogenic program.

Autosomal dominant polycystic kidney disease (ADPKD) arises from mutations in polycystin-1/PKD1 or p...

Aug 2026 42597841
Integrative multi-omics reveals a prognostic and therapeutic landscape of synthetic lethality-associated signatures in lung adenocarcinoma.

Lung adenocarcinoma (LUAD) exhibits considerable heterogeneity and therapeutic resistance. Here, we ...

(1)
Aug 2026 42597961
Predicting antifouling paint particle contamination based on 16S rRNA gene sequencing data using random forest-based machine learning.

Antifouling paints often contain biocides designed to inhibit biological growth, and antifouling pai...

(1)
Aug 2026 42545017
UCtracker: A Deep Learning-Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study.

Noninvasive diagnosis and longitudinal surveillance of urothelial carcinoma (UC) remain clinically c...

Aug 2026 42545181
Prognostication in Autosomal Dominant Polycystic Kidney Disease: Current Tools, Clinical Gaps, and Future Directions.

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent hereditary kidney disorde...

Aug 2026 42545852
Deep learning-supported image quantification of epithelial cell shapes and its application to polycystic kidney disease.

Cell shape is a fundamental determinant of tissue architecture and organ function. In epithelial tis...

(2)
Aug 2026 42546061
Integrative transcriptomics and single-cell analysis identify SIX4 as a candidate epithelial target in ovarian cancer and PCOS-associated ovarian dysregulation.

PURPOSE: Ovarian cancer is a heterogeneous solid tumor, whereas polycystic ovary syndrome (PCOS) is ...

(1)
Aug 2026 42546664
Advances in RNA pesticides and nano-delivery systems.

RNA pesticides have garnered considerable attention in pest management due to their exceptional sele...

(7)
Aug 2026 42546948
CHRNA5 orchestrates tumorigenesis and immune invasion through the CaMKII/AKT/NF-κB-CCL20 axis in pancreatic ductal adenocarcinoma.

AIMS: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by poo...

(3)
Aug 2026 42547009
Cancer drug response and resistance: molecular mechanisms and combating strategies.

Despite remarkable advances in cancer drug treatment, including chemotherapy, targeted therapy, and ...

(2)
Aug 2026 42543381
Selective taste impairment in relapsing-remitting Multiple Sclerosis and Supervised Learning - driven diagnostic classification.

Taste disturbances have been largely overlooked in Multiple Sclerosis (MS), despite mounting evidenc...

Aug 2026 42570510
Optimizing Cancer Drug Treatments Using Big Data Integration of Genomic and Clinical Data for Personalized Medicine.

Personalized cancer care depends on the seamless integration of genetic profiles, medical histories,...

Aug 2026 42543192
Integrating network toxicology, machine learning, and single-cell sequencing systems to analyze autophagy core genes in lung adenocarcinoma.

The heterogeneity and complex tumor microenvironment of lung adenocarcinoma lead to poor prognosis. ...

(5)
Aug 2026 42542475
Leveraging pretrained vision transformers for classifying alcohol use disorder using raw resting-state EEG.

Alcohol Use Disorder (AUD) is a prevalent neuropsychiatric condition affecting about 28 million adul...

(1)
Aug 2026 42576984
Integrated Network Analysis Suggests an miR-21/MMP/VEGF-Associated Regulatory Axis in Gastric Cancer.

BACKGROUND, AIMS: Gastric cancer (GC) pathogenesis involves complex molecular interactions that rema...

Aug 2026 42538731
Genome-wide analysis of subcortical aging identifies a spatially structured pattern of genetic associations.

Local brain age (LBA) is a spatially resolved biomarker of brain aging that captures regional deviat...

(5)
Aug 2026 42541656
Identification of TNFRSF12A as a key regulator of stemness and immunosuppression in a novel glioma subtype via multi-omics analysis and experimental validation.

Glioma stem cells (GSCs) drive tumor heterogeneity, therapy resistance, and immunosuppression. This ...

(2)
Aug 2026 42542235
Can We Improve the Prediction of Early Onset Mania and Hypomania in the Community?

BACKGROUND: There is broad agreement that the onset of bipolar disorders (BD) can be predicted by us...

(2)
Aug 2026 42358081
Deep mutational scanning of SARS-CoV-2 nucleocapsid reveals regional stability patterns.

Point mutations within the SARS-CoV-2 nucleocapsid protein (NP) have the potential to impact not onl...

Aug 2026 42423125
Persistent sheaf Laplacian analysis of protein stability and solubility changes upon mutation.

Genetic mutations frequently disrupt protein structure, stability, and solubility, acting as primary...

Aug 2026 42428996
Multiancestry and Multitrait GWAS Meta-Analysis on Schizophrenia With a Sample of 322,321 Unveils Genetic Links to Chronic Lung Diseases.

Schizophrenia (SCZ) is a highly heritable psychiatric disorder, yet its genetic links with chronic p...

Aug 2026 42444093
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