Latest AI and machine learning research in genetics for healthcare professionals.
Electronic health records (EHRs) have become the cornerstone of population-scale genetic studies1, b...
Immunotherapy with immune checkpoint inhibitors and immunotherapy combined with chemotherapy have re...
Understanding spatial organization of cells is critical for deciphering tissue function and disease....
Bacterial proteins are specialized with extensive functional diversity for survival in diverse and s...
Mobile genetic elements and genomic islands (GIs) frequently encode antibiotic resistance and host-a...
We introduce a workflow that integrates BioEmu-generated conformational ensemble with physics-based ...
Although prime editing (PE) can effect virtually any specified local change to genomic DNA in living...
Protein structure prediction using deep learning has revolutionized protein design. Yet, our underst...
Single-cell RNA sequencing enables high-resolution characterization of cellular heterogeneity, yet i...
Genomic sequences span billions of base pairs (bp), posing a fundamental challenge for genome-scale ...
Predicting functional consequences of genetic variants in crop genes remains a critical bottleneck f...
The role of intragenic cytosine methylation in shaping phenotypes has been contentious. Recent studi...
Alternative splicing is a core determinant of cell-type-specific gene expression in humans, and its ...
Banana and plantain (Musa spp.) production in Sub-Saharan Africa is severely constrained by multiple...
Antisense oligonucleotides (ASOs) are a promising class of therapeutic agents capable of selectively...
With the introduction of cyber-physical genome sequencing and editing technologies, such as CRISPR, ...
Single-cell RNA sequencing (scRNA-seq) data exhibit strong and reproducible statistical structure. T...
Abstract. Genetic diagnosis remains a formidable challenge characterized by a diagnostic odyssey tha...
Hypothalamic-pituitary-adrenal axis (HPA axis) dysregulation is a risk factor for poor mental and ph...
Standard approaches to bacterial phenotyping often treat the entire genome as the fundamental unit o...
Understanding how perturbations influence gene function in a tissue-specific manner is key to uncove...