Latest AI and machine learning research in genetics for healthcare professionals.
Multiplexed protein imaging enables spatially resolved analysis of molecular organization in tissues...
Single-cell RNA sequencing (scRNA-seq) data exhibit strong and reproducible statistical structure. T...
RNA design, the task of finding a sequence that folds into a target secondary structure, has broad b...
Fanconi anemia (FA) is a rare genetic disorder of impaired DNA repair characterized by progressive b...
Developing T cell receptors (TCRs) with sufficiently high affinity for tumor antigens (TAs) remains ...
Circulating tumor DNA (ctDNA) profiling from liquid biopsies is increasingly adopted as a minimally ...
Machine learning (ML) methods for proteins and RNAs rely on multiple sequence alignments (MSAs) and ...
Pancreatic ductal adenocarcinoma remains one of the most lethal malignancies, largely due to the abs...
DNA methylation is an established biomarker of human ageing, and analysing CpGs grouped by transcrip...
Recent advances in 3D Large Multimodal Models (LMMs) built on Large Language Models (LLMs) have esta...
Genomic foundation models have the potential to decode DNA syntax, yet face a fundamental tradeoff i...
Congenital anomalies of the kidney and urinary tract (CAKUT) are the leading cause of pediatric kidn...
OBJECTIVES Osteoarthritis is a heterogeneous disease, with diverse structural patterns likely reflec...
The microbial and biochemical landscape of clinically normal-appearing skin in individuals with acne...
ABSTRACT Small interfering RNAs (siRNAs) provide a promising therapeutic approach capable of selecti...
Existing methods for dynamic analysis of static single-cell RNA-sequencing data can reconstruct temp...
Objective: The immune system plays a role in the occurrence and progression of numerous pregnancy co...
Oxidative stress (OS) is a key factor in ischemic stroke (IS), but the characterization of OS-relate...
Predicting how genetic perturbations change cellular state is a core problem for building controllab...
POLE sequencing for somatic mutations (POLEmut) guides adjuvant therapy in endometrial cancer (EC), ...
Decoding gene expression from epigenomic landscapes remains a fundamental challenge in genomics. We ...