Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 7393-7413 of 11,216 articles
Beyond Flat Text: Dual Self-inherited Guidance for Visual Text Generation

In real-world images, slanted or curved texts, especially those on cans, banners, or badges, appea...

Using core genome and machine learning for serovar prediction in Salmonella enterica subspecies I strains.

This study presents a dual investigation of Salmonella enterica subspecies I, focusing on serovar pr...

Jan 2025 40210591
Machine Learning and statistical classification of CRISPR-Cas12a diagnostic assays

CRISPR-based diagnostics have gained increasing attention as biosensing tools able to address limi...

CSI-GEP: A GPU-based unsupervised machine learning approach for recovering gene expression programs in atlas-scale single-cell RNA-seq data.

Exploratory analysis of single-cell RNA sequencing (scRNA-seq) typically relies on hard clustering o...

Jan 2025 39788105
Identification of CXCR4 inhibitory activity in natural compounds using cheminformatics-guided machine learning algorithms.

Neurodegenerative disorders are characterised by progressive damage to neurons that leads to cogniti...

Jan 2025 39985292
TrojanDec: Data-free Detection of Trojan Inputs in Self-supervised Learning

An image encoder pre-trained by self-supervised learning can be used as a general-purpose feature ...

Explainable AI model reveals disease-related mechanisms in single-cell RNA-seq data

Neurodegenerative diseases (NDDs) are complex and lack effective treatment due to their poorly und...

CircaKB: a comprehensive knowledgebase of circadian genes across multiple species.

Circadian rhythms, which are the natural cycles that dictate various physiological processes over a ...

Jan 2025 39329269
PanKB: An interactive microbial pangenome knowledgebase for research, biotechnological innovation, and knowledge mining.

The exponential growth of microbial genome data presents unprecedented opportunities for unlocking t...

Jan 2025 39574409
miRStart 2.0: enhancing miRNA regulatory insights through deep learning-based TSS identification.

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to the 3'-untr...

Jan 2025 39578697
Optimal Inference of Asynchronous Boolean Network Models

Associations between phenotype and genomic and epigenomic markers are often derived by correlation...

iTARGET: Interpretable Tailored Age Regression for Grouped Epigenetic Traits

Accurately predicting chronological age from DNA methylation patterns is crucial for advancing bio...

METAGENE-1: Metagenomic Foundation Model for Pandemic Monitoring

We pretrain METAGENE-1, a 7-billion-parameter autoregressive transformer model, which we refer to ...

Knowledge-Guided Biomarker Identification for Label-Free Single-Cell RNA-Seq Data: A Reinforcement Learning Perspective

Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomi...

Deep Learning-Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy.

PURPOSE: To quantify outer retina structural changes and define novel biomarkers of inherited retina...

Jan 2025 39745677
Accurate prediction of gene deletion phenotypes with Flux Cone Learning

Predicting the impact of gene deletions is crucial for biological discovery, biomedicine, and biotec...

Marker-independent imaging reveals a correlation of fibrotic and epigenetic alterations in endometriosis

Endometriosis describes the presence of endometrial glands outside of the uterus and can cause vario...

RNAGenesis: A Generalist Foundation Model for Functional RNA Therapeutics

RNA molecules are central to gene regulation, catalysis, and molecular recognition, and offer broad ...

Fluctuation structure predicts genome-wide perturbation outcomes

Pooled single-cell perturbation screens represent powerful experimental platforms for functional gen...

GARN3: A coarse-grained helix centered technique for RNA 3D structures prediction

The study of the prediction of three-dimensional structures of RNA (ribonucleic acids) has been incr...

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