Latest AI and machine learning research in genetics for healthcare professionals.
Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine-learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with ranking for selection of single nucleotide polymorphisms (SNP) for fine-sc...
3,4- methylenedioxymethamphetamine (MDMA) is a chemical derivative of amphetamine that can induce learning and memory impairment. Due to the effect of neurotrophins on memory and learning, the impact of MDMA was evaluated on the brain - derived neurotrophic factor (BDNF), neurotrophin- 4 (NT-4), and tropomyosin- related kinase B (Trk- β) expression in the hippocampus. In this study, 20 adult mal...
In this study, gene expression profiles of osteosarcoma (OS) were analyzed to identify critical genes associated with metastasis. Five gene expression...
Gene Ontology (GO) analysis is a powerful tool in systems biology, which uses a defined nomenclature to annotate genes/proteins within three categorie...
The development of breast cancer is influenced by the adipose tissue through the proteins leptin and adiponectin. However, there is little research co...
OBJECTIVE: Finding the human genes co-causing complex diseases, also known as "disease-genes", is one of the emerging and challenging tasks in biomedi...
MGMT promoter methylation and IDH1 mutation in high-grade gliomas (HGG) have proven to be the two important molecular indicators associated with bette...
Proteins are the macromolecules responsible for almost all biological processes in a cell. With the availability of large number of protein sequences ...
BACKGROUND AND OBJECTIVES: We introduce the R-package GenomicTools to perform, among others, a Multifactor Dimensionality Reduction (MDR) for the iden...
Vitamin D deficiency is prevalent in the Arabian Gulf region, especially among women. Recent studies show that the vitamin D deficiency is associated ...
Respiratory viral diseases can be spread when a virus-containing particle (droplet) from one individual is aerosolized and subsequently comes into eit...
INTRODUCTION: Stroke is a multifactorial and heterogeneous disorder, correlates with heritability and considered as one of the major diseases. The pri...
Helix-helix interactions are crucial in the structure assembly, stability and function of helix-rich proteins including many membrane proteins. In spi...
Spiking neural P systems (SNP systems, in short) are a class of distributed parallel computing systems inspired from the neurophysiological behavior o...
The aim of the study is to investigate the impact of SELP and IL-6 genetic single-nucleotide polymorphisms (SNPs) and its gene-gene interaction on car...
Hereditary haemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease, is a rare, vascular, autosomal dominant disorder. The purpose o...
BACKGROUND: This study was conducted to assess the effect of percutaneous coronary revascularization (PCR) on plasma NT-proBNP concentration in patien...
The molecular evolution of genomic DNA across diverse plant and animal phyla involved dynamic registrations of sequence modifications to maintain exis...
In less than a decade, big data in medicine has become quite a phenomenon and many biomedical disciplines got their own tribune on the topic. Perspect...
Network-based analytics plays an increasingly important role in precision oncology. Growing evidence in recent studies suggests that cancer can be bet...