Latest AI and machine learning research in genetics for healthcare professionals.
Multimodal neural networks integrating protein language models (PLMs) with structure-derived feature...
Single-cell RNA sequencing (scRNA-seq) enables characterization of cellular heterogeneity but lacks ...
Deciphering the connectome, anatomy, transcriptome and spatial-omics integrated multi-modal brain at...
Single-cell RNA sequencing technologies have revolutionized our understanding of cellular heterogene...
Adaptive introgression (AI), the beneficial genetic transfer between species, is key to adaptation, ...
Single-cell RNA sequencing (scRNA-seq) has significantly advanced our understanding of Alzheimer’s d...
EGFR amplification occurs in approximately 40-50% of glioblastoma (GBM) cases and is critical for tr...
Small interfering RNA (siRNA) therapeutics have extraordinary potential for targeted gene silencing....
Early detection of hepatocellular carcinoma (HCC) is critical for improving patient outcomes, yet cu...
The accurate duplication of the genome relies on the spatiotemporal control of DNA replication initi...
The CACNA1C gene encodes the CaV1.2 L-type voltage-gated calcium channel, which plays a crucial role...
Cis-regulatory elements shape gene expression by recruiting transcription factors (TFs) to DNA motif...
Disseminated (DTCs) and circulating tumor cells (CTCs) are rare but pivotal in understanding cancer ...
The regulation of mRNA decay and translation is crucial for cellular function and development; howev...
The development of modern genome editing and DNA synthesis has enabled researchers to edit DNA seque...
Cell biology has been booming with foundation models trained on large single-cell RNA-seq databases,...
Acute myeloid leukemia (AML) often enters remission after chemotherapy but frequently relapses due t...
The growing number of spot-resolution sequencing based spatial transcriptomic (ST) datasets provides...
Microorganisms underpin global biogeochemical cycles and represent a vast, underexplored reservoir f...
Cell-free RNA (cfRNA) in human plasma provides a minimally invasive readout of tissue physiology, ye...
Proteostasis dysfunction is a hallmark of frontotemporal dementia (FTD) and Alzheimer’s disease (AD)...