Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 8065-8085 of 11,255 articles
Prediction of impulse control disorders in Parkinson’s disease: a longitudinal machine learning study

Impulse control disorders (ICD) in Parkinson’s disease (PD) patients mainly occur as adverse effects...

AI-Driven Personalization of Dual Antiplatelet Therapy Duration Post-PCI: A Novel Approach Balancing Ischemic and Bleeding Risks

Precision-guided dual antiplatelet therapy (DAPT) duration post-percutaneous coronary intervention (...

Advancing sarcoma diagnostics with expanded DNA methylation-based classification

Sarcomas pose a severe diagnostic challenge. A wide variety of these distinct entities need to be di...

Omics Integration Uncovers Mechanisms Associated with HIV Viral Load and Potential Therapeutic Insights

While antiretroviral therapy (ART) has significantly improved disease prognosis in people with HIV (...

MOKA: A pipeline for multi-omics bridged SNP-set kernel association test

The explosion of genomic and multi-omics data has created a need for scalable, reproducible tools th...

Genetic Profiling and Early Detection of Type 2 Diabetes Subtypes through Sex-Stratified GWAS and Explainable AI

Type 2 diabetes (T2D) is a complex and clinically heterogeneous disease. Although clustering approac...

Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures

Obesity, a leading global risk factor for cardiometabolic conditions, arises from multifaceted and b...

Multimodal Integration of Alzheimer’s Plasma Biomarkers, MRI, and Genetic Risk for Individual Prediction of Cerebral Amyloid Burden

Alzheimer’s disease (AD), the most prevalent neurodegenerative disorder, is marked by the accumulati...

Prematurity and Genetic Liability for Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by diverse presentati...

Network-Based Stratification Refines Stratification of Intermediate-Risk Acute Myeloid Leukemia Samples

The European LeukemiaNet (ELN) risk stratification of acute myeloid leukemia (AML) uses genetic and ...

Polygenic prediction of phenotypes with a neural empirical Bayes approach

Polygenic risk scores (PRS) estimate the expected value of a phenotype based on individual genotypes...

Explainable AI for Precision Oncology: A Task-Specific Approach Using Imaging, Multi-omics, and Clinical Data

Despite continued advances in oncology, cancer remains a leading cause of global mortality, highligh...

Translation of miRNA blood-based discovery to molecular testing for clinical diagnosis of endometriosis

Endometriosis is a common yet often underdiagnosed condition, partly due to the lack of reliable dia...

A clinically relevant morpho-molecular classification of lung neuroendocrine tumours

Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwi...

Genetic regulation of cell type–specific chromatin accessibility shapes immune function and disease risk

Understanding how genetic variation influences gene regulation at the single-cell level is crucial f...

Complex pathways to ceftolozane-tazobactam resistance in clinical Pseudomonas aeruginosa isolates: a genomic epidemiology study

We aimed to conduct a comprehensive genomic analysis of ceftolozane/tazobactam (C/T) resistance mech...

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