Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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DRB1 Subtyping Reveals Divergent Risk and Protection for Type 1 Diabetes in Middle Eastern Populations

Type 1 diabetes (T1D) is strongly influenced by HLA variation, yet current genetic risk models devel...

Integration of T cell repertoire, CyTOF, genotyping and symptomatology data reveals subphenotypic variability in COVID-19 patients.

COVID-19 manifests a broad spectrum of clinical outcomes, from asymptomatic cases to severe disease....

Jan 2025 40502932
RNA knowledge-graph analysis through homogeneous embedding methods.

MOTIVATION: We recently introduced RNA-knowledge graph (KG), an ontology-based KG that integrates bi...

Jan 2025 40496493
Intimate partner violence and stress-related disorders: from epigenomics to resilience.

Intimate Partner Violence (IPV) is a major public health problem to be addressed with innovative and...

Jan 2025 40421256
Prediction of KRAS gene mutations in colorectal cancer using a CT-based radiomic model.

BACKGROUND: Determining the KRAS gene mutation status in colorectal cancer (CRC) before surgery is h...

Jan 2025 40421293
Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data.

Graph Neural Networks (GNNs) have emerged as powerful tools for analyzing structured data, particula...

Jan 2025 40421418
m5CStack: An integrated framework for m5C site prediction using multi-feature stacking.

RNA 5-methylcytosine (m5C) modification sites are essential for understanding the regulation of RNA ...

Jan 2025 40487198
Donor-specific digital twin for living donor liver transplant recovery.

The remarkable capacity of the liver to regenerate its lost mass after resection makes living donor ...

Jan 2025 40486178
Pyroptosis-Related Gene Signatures Enable Robustly Diagnosis, Prognosis and Immune Responses Prediction in Uterine Corpus Endometrial Carcinoma.

Uterine corpus endometrial carcinoma (UCEC) is a gynecological malignancy with poor prognosis and h...

Jan 2025 40535818
Leveraging molecular-QTL co-association to predict novel disease-associated genetic loci using a graph convolutional neural network.

Genome-wide association studies (GWAS) have successfully uncovered numerous associations between gen...

Jan 2025 40493586
Advanced multi-objective trajectory planning for robotic arms using a multi-strategy enhanced NSGA-II algorithm.

Facing the problems of large-scale rapid and disorderly loading, the robotic arm has the problems of...

Jan 2025 40440297
Identification of hub gene for the pathogenic mechanism and diagnosis of MASLD by enhanced bioinformatics analysis and machine learning.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous disease caused b...

Jan 2025 40435176
Leveraging transformers and explainable AI for Alzheimer's disease interpretability.

Alzheimer's disease (AD) is a progressive brain ailment that causes memory loss, cognitive decline, ...

Jan 2025 40408321
Hybrid deep learning model for accurate and efficient android malware detection using DBN-GRU.

The rapid growth of Android applications has led to an increase in security threats, while tradition...

Jan 2025 40388500
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