Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 8464-8484 of 11,255 articles
Scaling Up Single Image Dehazing Algorithm by Cross-Data Vision Alignment for Richer Representation Learning and Beyond

In recent years, deep neural networks tasks have increasingly relied on high-quality image inputs....

A comprehensive survey on deep learning-based identification and predicting the interaction mechanism of long non-coding RNAs.

Long noncoding RNAs (lncRNAs) have been discovered to be extensively involved in eukaryotic epigenet...

Jul 2024 38576205
SpaDiT: Diffusion Transformer for Spatial Gene Expression Prediction using scRNA-seq

The rapid development of spatial transcriptomics (ST) technologies is revolutionizing our understa...

Multi-Modal and Multi-Attribute Generation of Single Cells with CFGen

Generative modeling of single-cell RNA-seq data is crucial for tasks like trajectory inference, ba...

Genomic Language Models: Opportunities and Challenges

Large language models (LLMs) are having transformative impacts across a wide range of scientific f...

Bridging Sequence-Structure Alignment in RNA Foundation Models

The alignment between RNA sequences and structures in foundation models (FMs) has yet to be thorou...

FastImpute: A Baseline for Open-source, Reference-Free Genotype Imputation Methods -- A Case Study in PRS313

Genotype imputation enhances genetic data by predicting missing SNPs using reference haplotype inf...

Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows†.

The objective was to identify a set of genes whose transcript abundance is predictive of a cow's abi...

Jul 2024 38590174
High-Performance Sorting-Based k-mer Counting in Distributed Memory with Flexible Hybrid Parallelism

In generating large quantities of DNA data, high-throughput sequencing technologies require advanc...

Generating, modeling and evaluating a large-scale set of CRISPR/Cas9 off-target sites with bulges.

The CRISPR/Cas9 system is a highly accurate gene-editing technique, but it can also lead to unintend...

Jul 2024 38813823
Dy-mer: An Explainable DNA Sequence Representation Scheme using Sparse Recovery

DNA sequences encode vital genetic and biological information, yet these unfixed-length sequences ...

iM-Seeker: a webserver for DNA i-motifs prediction and scoring via automated machine learning.

DNA, beyond its canonical B-form double helix, adopts various alternative conformations, among which...

Jul 2024 38676949
DDMut-PPI: predicting effects of mutations on protein-protein interactions using graph-based deep learning.

Protein-protein interactions (PPIs) play a vital role in cellular functions and are essential for th...

Jul 2024 38783112
Semantically Rich Local Dataset Generation for Explainable AI in Genomics

Black box deep learning models trained on genomic sequences excel at predicting the outcomes of di...

TransCell: In Silico Characterization of Genomic Landscape and Cellular Responses by Deep Transfer Learning.

Gene expression profiling of new or modified cell lines becomes routine today; however, obtaining co...

Jul 2024 39240541
SeqMate: A Novel Large Language Model Pipeline for Automating RNA Sequencing

RNA sequencing techniques, like bulk RNA-seq and Single Cell (sc) RNA-seq, are critical tools for ...

Deep learning with a small dataset predicts chromatin remodelling contribution to winter dormancy of apple axillary buds.

Epigenetic changes serve as a cellular memory for cumulative cold recognition in both herbaceous and...

Jul 2024 38905284
A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis.

Patient-derived xenografts (PDX) model human intra- and intertumoral heterogeneity in the context of...

Jul 2024 39082680
DeepGSEA: explainable deep gene set enrichment analysis for single-cell transcriptomic data.

MOTIVATION: Gene set enrichment (GSE) analysis allows for an interpretation of gene expression throu...

Jul 2024 38950178
SFINN: inferring gene regulatory network from single-cell and spatial transcriptomic data with shared factor neighborhood and integrated neural network.

MOTIVATION: The rise of single-cell RNA sequencing (scRNA-seq) technology presents new opportunities...

Jul 2024 38950180
Advancing lung adenocarcinoma prognosis and immunotherapy prediction with a multi-omics consensus machine learning approach.

Lung adenocarcinoma (LUAD) is a tumour characterized by high tumour heterogeneity. Although there ar...

Jul 2024 38958523
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