Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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JAKCalc: A machine-learning approach to rationalized JAK2 testing in patients with elevated hemoglobin levels.

The demand for Janus Kinase-2 (JAK2) testing has been disproportionate to the low yield of positive ...

Apr 2024 38579024
Advanced Technologies in Radiation Research.

The U.S. Government is committed to maintaining a robust research program that supports a portfolio ...

Apr 2024 38453643
Identification of circRNA-disease associations via multi-model fusion and ensemble learning.

Circular RNA (circRNA) is a common non-coding RNA and plays an important role in the diagnosis and t...

Apr 2024 38506066
Integration of graph network with kernel SVM and logistic regression for identification of biomarkers in SCA12 and its diagnosis.

Spinocerebellar ataxia type 12 is a hereditary and neurodegenerative illness commonly found in India...

Apr 2024 38679476
Contrastive pre-training and 3D convolution neural network for RNA and small molecule binding affinity prediction.

MOTIVATION: The diverse structures and functions inherent in RNAs present a wealth of potential drug...

Mar 2024 38507691
Clustering single-cell multi-omics data via graph regularized multi-view ensemble learning.

MOTIVATION: Single-cell clustering plays a crucial role in distinguishing between cell types, facili...

Mar 2024 38547401
Coding genomes with gapped pattern graph convolutional network.

MOTIVATION: Genome sequencing technologies reveal a huge amount of genomic sequences. Neural network...

Mar 2024 38603603
scNovel: a scalable deep learning-based network for novel rare cell discovery in single-cell transcriptomics.

Single-cell RNA sequencing has achieved massive success in biological research fields. Discovering n...

Mar 2024 38555470
D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer.

As key oncogenic drivers in non-small-cell lung cancer (NSCLC), various mutations in the epidermal g...

Mar 2024 38555474
From tradition to innovation: conventional and deep learning frameworks in genome annotation.

Following the milestone success of the Human Genome Project, the 'Encyclopedia of DNA Elements (ENCO...

Mar 2024 38581418
HyGAnno: hybrid graph neural network-based cell type annotation for single-cell ATAC sequencing data.

Reliable cell type annotations are crucial for investigating cellular heterogeneity in single-cell o...

Mar 2024 38581422
Improving drug response prediction via integrating gene relationships with deep learning.

Predicting the drug response of cancer cell lines is crucial for advancing personalized cancer treat...

Mar 2024 38600666
DSNetax: a deep learning species annotation method based on a deep-shallow parallel framework.

Microbial community analysis is an important field to study the composition and function of microbia...

Mar 2024 38600668
DeepSS2GO: protein function prediction from secondary structure.

Predicting protein function is crucial for understanding biological life processes, preventing disea...

Mar 2024 38701416
BERT-TFBS: a novel BERT-based model for predicting transcription factor binding sites by transfer learning.

Transcription factors (TFs) are proteins essential for regulating genetic transcriptions by binding ...

Mar 2024 38701417
Optimal fusion of genotype and drug embeddings in predicting cancer drug response.

Predicting cancer drug response using both genomics and drug features has shown some success compare...

Mar 2024 38754407
EquiPNAS: improved protein-nucleic acid binding site prediction using protein-language-model-informed equivariant deep graph neural networks.

Protein language models (pLMs) trained on a large corpus of protein sequences have shown unprecedent...

Mar 2024 38281252
Prediction of DNA i-motifs via machine learning.

i-Motifs (iMs), are secondary structures formed in cytosine-rich DNA sequences and are involved in m...

Mar 2024 38364855
NPSV-deep: a deep learning method for genotyping structural variants in short read genome sequencing data.

MOTIVATION: Structural variants (SVs) play a causal role in numerous diseases but can be difficult t...

Mar 2024 38444093
Understanding gut microbiome-based machine learning platforms: A review on therapeutic approaches using deep learning.

Human beings possess trillions of microbial cells in a symbiotic relationship. This relationship ben...

Mar 2024 38491814
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