Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Plant Reactome Knowledgebase: empowering plant pathway exploration and OMICS data analysis.

Plant Reactome (https://plantreactome.gramene.org) is a freely accessible, comprehensive plant pathw...

Jan 2024 37986220
CADD v1.7: using protein language models, regulatory CNNs and other nucleotide-level scores to improve genome-wide variant predictions.

Machine Learning-based scoring and classification of genetic variants aids the assessment of clinica...

Jan 2024 38183205
Integration of transcriptome and machine learning to identify the potential key genes and regulatory networks affecting drip loss in pork.

Low level of drip loss (DL) is an important quality characteristic of meat with high economic value....

Jan 2024 38865489
IPEV: identification of prokaryotic and eukaryotic virus-derived sequences in virome using deep learning.

BACKGROUND: The virome obtained through virus-like particle enrichment contains a mixture of prokary...

Jan 2024 38649300
CheRRI-Accurate classification of the biological relevance of putative RNA-RNA interaction sites.

BACKGROUND: RNA-RNA interactions are key to a wide range of cellular functions. The detection of pot...

Jan 2024 38837942
RNAVirHost: a machine learning-based method for predicting hosts of RNA viruses through viral genomes.

BACKGROUND: The high-throughput sequencing technologies have revolutionized the identification of no...

Jan 2024 39172545
Deepdefense: annotation of immune systems in prokaryotes using deep learning.

BACKGROUND: Due to a constant evolutionary arms race, archaea and bacteria have evolved an abundance...

Jan 2024 39388605
Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin Database (VPOD).

BACKGROUND: Predicting phenotypes from genetic variation is foundational for fields as diverse as bi...

Jan 2024 39460934
A Comprehensive System for Searching and Evaluating Genomic Variant Evidence Using AI and Knowledge Bases to Support Personalized Medicine.

We introduce an innovative automated system for the search and assessment of genetic variant evidenc...

Jan 2024 40417484
Meta-Learning on Augmented Gene Expression Profiles for Enhanced Lung Cancer Detection.

Gene expression profiles obtained through DNA microarray have proven successful in providing critica...

Jan 2024 40417531
Unlocking Early Cancer Detection: Leveraging Machine Learning in Cell-Free DNA Analysis for Precision Oncology.

This study introduces a groundbreaking approach to early cancer detection through the analysis of ce...

Jan 2024 40417566
An effective deep learning-based approach for splice site identification in gene expression.

A crucial stage in eukaryote gene expression involves mRNA splicing by a protein assembly known as t...

Jan 2024 39051530
Pentagon Found Daily, Metagenomic Detection of Novel Bioaerosol Threats to Be Cost-Prohibitive: Can Virtualization and AI Make It Cost-Effective?

In 2022, the Pentagon Force Protection Agency found threat agnostic detection of novel bioaerosol th...

Jan 2024 38625036
Deep Learning for Predicting Gene Regulatory Networks: A Step-by-Step Protocol in R.

Deep learning has emerged as a powerful tool for solving complex problems, including reconstruction ...

Jan 2024 37803123
Machine Learning Strategies for Improved Phenotype Prediction in Underrepresented Populations.

Precision medicine models often perform better for populations of European ancestry due to the over-...

Jan 2024 38160295
Multi-omics Combined with Machine Learning Facilitating the Diagnosis of Gastric Cancer.

Gastric cancer (GC) is a highly intricate gastrointestinal malignancy. Early detection of gastric ca...

Jan 2024 38351697
Identifying Hub Genes for Glaucoma based on Bulk RNA Sequencing Data and Multi-machine Learning Models.

AIMS: The aims of this study were to determine hub genes in glaucoma through multiple machine learni...

Jan 2024 38362683
Prediction of LncRNA-protein Interactions Using Auto-Encoder, SE-ResNet Models and Transfer Learning.

BACKGROUND: Long non-coding RNA (lncRNA) plays a crucial role in various biological processes, and m...

Jan 2024 38591194
Classification of DNA Sequence Based on a Non-gradient Algorithm: Pseudoinverse Learners.

This chapter proposes a prototype-based classification approach for analyzing DNA barcodes that uses...

Jan 2024 38683331
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