Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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The hitchhikers' guide to RNA sequencing and functional analysis.

DNA and RNA sequencing technologies have revolutionized biology and biomedical sciences, sequencing ...

Jan 2023 36617463
RNAdegformer: accurate prediction of mRNA degradation at nucleotide resolution with deep learning.

Messenger RNA-based therapeutics have shown tremendous potential, as demonstrated by the rapid devel...

Jan 2023 36633966
Integrated mRNA sequence optimization using deep learning.

The coronavirus disease of 2019 pandemic has catalyzed the rapid development of mRNA vaccines, where...

Jan 2023 36642413
Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group.

PURPOSE: Rhabdomyosarcoma (RMS) is an aggressive soft-tissue sarcoma, which primarily occurs in chil...

Jan 2023 36346688
AgeAnno: a knowledgebase of single-cell annotation of aging in human.

Aging is a complex process that accompanied by molecular and cellular alterations. The identificatio...

Jan 2023 36200838
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database.

The Comprehensive Antibiotic Resistance Database (CARD; card.mcmaster.ca) combines the Antibiotic Re...

Jan 2023 36263822
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource.

The NHGRI-EBI GWAS Catalog (www.ebi.ac.uk/gwas) is a FAIR knowledgebase providing detailed, structur...

Jan 2023 36350656
IDEFE algorithm: IDE algorithm optimizes the fuzzy entropy for the gland segmentation.

Breast cancer occurs in the epithelial tissue of the gland, so the accuracy of gland segmentation is...

Jan 2023 36896528
Biomarkers of aging - current state of knowledge.

Aging is a process of gradual decline in the functional capacity of the human body that leads to a s...

Jan 2023 37923561
Prediction of Breast Cancer Through Random Forest.

BACKGROUND: 8% of women are diagnosed with breast cancer. (BC) BC is the second most common cause of...

Jan 2023 36200251
Prediction of Cancer Treatment Using Advancements in Machine Learning.

Many cancer patients die due to their treatment failing because of their disease's resistance to che...

Jan 2023 36263487
Analyzing Antibody Repertoire Using Next-Generation Sequencing and Machine Learning.

Advances in high-throughput sequencing technologies have enabled comprehensive sequencing of the imm...

Jan 2023 36346609
Differential Expression, Functional and Machine Learning Analysis of High-Throughput -Omics Data Using Open-Source Tools.

Today, -omics analyses, including the systematic cataloging of messenger RNA and microRNA sequences ...

Jan 2023 36418696
DeepPHiC: predicting promoter-centered chromatin interactions using a novel deep learning approach.

MOTIVATION: Promoter-centered chromatin interactions, which include promoter-enhancer (PE) and promo...

Jan 2023 36495179
ResidualBind: Uncovering Sequence-Structure Preferences of RNA-Binding Proteins with Deep Neural Networks.

Deep neural networks have demonstrated improved performance at predicting sequence specificities of ...

Jan 2023 36705906
Applying Machine Learning to Classify the Origins of Gene Duplications.

Nearly all lineages of land plants have experienced at least one whole-genome duplication (WGD) in t...

Jan 2023 36720809
How data science and AI-based technologies impact genomics.

Advancements in high-throughput sequencing have yielded vast amounts of genomic data, which are stud...

Jan 2023 36722518
A Guide to MethylationToActivity: A Deep Learning Framework That Reveals Promoter Activity Landscapes from DNA Methylomes in Individual Tumors.

Genome-wide DNA methylomes have contributed greatly to tumor detection and subclassification. Howeve...

Jan 2023 36723810
Deep Learning on Chromatin Accessibility.

DNA accessibility has been a powerful tool in locating active regulatory elements in a cell type, bu...

Jan 2023 36807077
DeepZ: A Deep Learning Approach for Z-DNA Prediction.

Here we describe an approach that uses deep learning neural networks such as CNN and RNN to aggregat...

Jan 2023 36892770
Robotic DNA Extraction Utilizing Qiagen BioSprint 96 Workstation.

After an examination of evidentiary or reference samples has been performed, the next step is DNA ex...

Jan 2023 37439976
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