Genetics

Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

11,273 articles

Subcategories: Genetics

Showing 8821-8841 of 11,273 articles

High-throughput single-cell RNA-seq data imputation and characterization with surrogate-assisted automated deep learning.

Single-cell RNA sequencing (scRNA-seq) technologies have been heavily developed to probe gene expres...

Jan 2022 34553763

circRNA-binding protein site prediction based on multi-view deep learning, subspace learning and multi-view classifier.

Circular RNAs (circRNAs) generally bind to RNA-binding proteins (RBPs) to play an important role in ...

Jan 2022 34571539

Assessing deep learning methods in cis-regulatory motif finding based on genomic sequencing data.

Identifying cis-regulatory motifs from genomic sequencing data (e.g. ChIP-seq and CLIP-seq) is cruci...

Jan 2022 34607350

Deep learning-based advances and applications for single-cell RNA-sequencing data analysis.

The rapid development of single-cell RNA-sequencing (scRNA-seq) technology has raised significant co...

Jan 2022 34849562

NmRF: identification of multispecies RNA 2'-O-methylation modification sites from RNA sequences.

2'-O-methylation (Nm) is a post-transcriptional modification of RNA that is catalyzed by 2'-O-methyl...

Jan 2022 34850821

DeepDISOBind: accurate prediction of RNA-, DNA- and protein-binding intrinsically disordered residues with deep multi-task learning.

Proteins with intrinsically disordered regions (IDRs) are common among eukaryotes. Many IDRs interac...

Jan 2022 34905768

Protein-RNA interaction prediction with deep learning: structure matters.

Protein-RNA interactions are of vital importance to a variety of cellular activities. Both experimen...

Jan 2022 34929730

Deep learning tackles single-cell analysis-a survey of deep learning for scRNA-seq analysis.

Since its selection as the method of the year in 2013, single-cell technologies have become mature e...

Jan 2022 34929734

Prediction of disease-associated nsSNPs by integrating multi-scale ResNet models with deep feature fusion.

More than 6000 human diseases have been recorded to be caused by non-synonymous single nucleotide po...

Jan 2022 34953462

Heavy chain sequence-based classifier for the specificity of human antibodies.

Antibodies specifically bind to antigens and are an essential part of the immune system. Hence, anti...

Jan 2022 34953464

SIGNET: single-cell RNA-seq-based gene regulatory network prediction using multiple-layer perceptron bagging.

High-throughput single-cell RNA-seq data have provided unprecedented opportunities for deciphering t...

Jan 2022 34962260

Detection of transcription factors binding to methylated DNA by deep recurrent neural network.

Transcription factors (TFs) are proteins specifically involved in gene expression regulation. It is ...

Jan 2022 34962264

scMRA: a robust deep learning method to annotate scRNA-seq data with multiple reference datasets.

MOTIVATION: Single-cell RNA-seq (scRNA-seq) has been widely used to resolve cellular heterogeneity. ...

Jan 2022 34623390

EDCNN: identification of genome-wide RNA-binding proteins using evolutionary deep convolutional neural network.

MOTIVATION: RNA-binding proteins (RBPs) are a group of proteins associated with RNA regulation and m...

Jan 2022 34694393

LncRNAWiki 2.0: a knowledgebase of human long non-coding RNAs with enhanced curation model and database system.

LncRNAWiki, a knowledgebase of human long non-coding RNAs (lncRNAs), has been rapidly expanded by in...

Jan 2022 34751395

scEnhancer: a single-cell enhancer resource with annotation across hundreds of tissue/cell types in three species.

Previous studies on enhancers and their target genes were largely based on bulk samples that represe...

Jan 2022 34761274

The reactome pathway knowledgebase 2022.

The Reactome Knowledgebase (https://reactome.org), an Elixir core resource, provides manually curate...

Jan 2022 34788843

lncRNAfunc: a knowledgebase of lncRNA function in human cancer.

The long non-coding RNAs associating with other molecules can coordinate several physiological proce...

Jan 2022 34791419

A Deep-Learning Approach for Inference of Selective Sweeps from the Ancestral Recombination Graph.

Detecting signals of selection from genomic data is a central problem in population genetics. Coupli...

Jan 2022 34888675

Recent Progress of Machine Learning in Gene Therapy.

With new developments in biomedical technology, it is now a viable therapeutic treatment to alter ge...

Jan 2022 34161210

Hubness weighted SVM ensemble for prediction of breast cancer subtypes.

BACKGROUND: Breast cancer is a major disease causing panic among women worldwide. Since gene mutatio...

Jan 2022 34397436

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