Latest AI and machine learning research in genetics for healthcare professionals.
Numerous studies have linked gut microbiome alterations to colorectal cancer (CRC), but limited sample sizes and study heterogeneity have hampered cross-study comparisons and subgroup analyses. Here, we present a comprehensive single-disease gut microbiome meta-analysis based on consistently re-computed and re-analyzed shotgun and amplicon sequencing profiles (n = 6,779 samples, 27 studies). Assoc...
Glioblastoma is a highly aggressive brain tumor characterized by complex genetic, molecular, and epigenetic features that present significant challenges for treatment. This review explores recent advances in understanding the molecular and epigenetic landscape of glioblastoma, with particular emphasis on epigenetic modifications such as DNA methylation, histone changes, and N6-methyladenosine regu...
Genetic code expansion (GCE) provides a robust platform for engineering protein function via the site-specific incorporation of noncanonical amino aci...
This narrative review explores the latest advancements in various imaging modalities combined with artificial intelligence (AI) for monitoring respons...
Diabetic nephropathy (DN) is a leading cause of chronic kidney disease. Salvianolic acid A (SAA) has shown promising therapeutic potential against DN,...
BACKGROUND: This paper reports a genetic identification task using 3D convolutional neural network (3D-CNN) models applied to a proprietary 3D magneti...
Efficient and accurate identification of functional genes is critical to biological research, yet traditional single-species approaches are often limi...
BACKGROUND: Chikungunya fever (CHIKF) and dengue fever are mosquito-borne viral diseases. These infections often circulate in the same regions at the ...
BACKGROUND: Bladder cancer (BC) remains a prevalent malignancy with a high recurrence rate; however, the lack of specific biomarkers hinders early det...
Transcription factors (TFs) and nucleotide-binding leucine-rich repeat (NLR) genes are core components of the immune response in rice against Magnapor...
BACKGROUND: Circulating tumor DNA (ctDNA) detection offers minimally invasive monitoring of cancer from blood samples. While tumor-informed approaches...
While simplistic volcano plot visualizations of multi-omics changes can highlight the most critical genomic, transcriptomic, or proteomic features, in...
Saliva, a frequently encountered biological specimen in forensic investigations, has great potential to provide critical leads if the donor's age can ...
Identifying reproducible, interpretable prognostic signals from high-dimensional transcriptomics remains challenging because gene-level models often i...
Early and accurate diagnosis remains a major challenge in cervical cancer management. This study aimed to identify reliable diagnostic biomarkers for ...
Agriculture plays a crucial role in the development of countries whose economies rely heavily on food production. In the face of climate change and gr...
Marginal zone lymphoma (MZL) is an indolent B-cell non-Hodgkin lymphoma with marked heterogeneity. Currently, histological subtype, clinical stage, bi...
PURPOSE OF REVIEW: Children with hereditary polyposis syndromes require long-term endoscopic surveillance to reduce risks of gastrointestinal complica...
BACKGROUND: We compared performance across 3 breast cancer risk domains-clinical, polygenic, and mammography artificial intelligence-alone and in comb...