Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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DriverML: a machine learning algorithm for identifying driver genes in cancer sequencing studies.

Although rapid progress has been made in computational approaches for prioritizing cancer driver gen...

May 2019 30773592
Validity of Natural Language Processing for Ascertainment of and Test Results in SEER Cases of Stage IV Non-Small-Cell Lung Cancer.

PURPOSE: SEER registries do not report results of epidermal growth factor receptor () and anaplastic...

May 2019 31058542
EnsembleCNV: an ensemble machine learning algorithm to identify and genotype copy number variation using SNP array data.

The associations between diseases/traits and copy number variants (CNVs) have not been systematicall...

Apr 2019 30722045
WHISTLE: a high-accuracy map of the human N6-methyladenosine (m6A) epitranscriptome predicted using a machine learning approach.

N 6-methyladenosine (m6A) is the most prevalent post-transcriptional modification in eukaryotes, and...

Apr 2019 30993345
A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study.

Acute myeloid leukemia (AML) is a genetically heterogeneous hematological malignancy with variable r...

Apr 2019 31015209
Exploring sequence-based features for the improved prediction of DNA N4-methylcytosine sites in multiple species.

MOTIVATION: As one of important epigenetic modifications, DNA N4-methylcytosine (4mC) is recently sh...

Apr 2019 30239627
DeepGSR: an optimized deep-learning structure for the recognition of genomic signals and regions.

MOTIVATION: Recognition of different genomic signals and regions (GSRs) in DNA is crucial for unders...

Apr 2019 30184052
ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine.

Since the discovery of 5-hydroxymethylcytosine (5hmC) as a prominent DNA modification found in mamma...

Mar 2019 30649543
Hybrid 11C-MET PET/MRI Combined With "Machine Learning" in Glioma Diagnosis According to the Revised Glioma WHO Classification 2016.

PURPOSE: With the advent of the revised WHO classification from 2016, molecular features, including ...

Mar 2019 30516675
[Machine Learning Applications in Cancer Genome Medicine].

Practical cancer genome medicine requires large-scale data analysis for many types of biological dat...

Mar 2019 30914576
Machine Learning as an Effective Method for Identifying True Single Nucleotide Polymorphisms in Polyploid Plants.

Single nucleotide polymorphisms (SNPs) have many advantages as molecular markers since they are ubiq...

Mar 2019 30951095
[Effects of long non-coding RNA RP1-90L14.1 on the biological behaviors of cancer prostate LNCaP cells and its regulating mechanisms].

OBJECTIVE: To investigate the effects of long non-coding RNA RP1-90L14.1 on the proliferation, migra...

Mar 2019 32216238
GOF/LOF knowledge inference with tensor decomposition in support of high order link discovery for gene, mutation and disease.

For discovery of new usage of drugs, the function type of their target genes plays an important role...

Feb 2019 30947425
4mCPred: machine learning methods for DNA N4-methylcytosine sites prediction.

MOTIVATION: N4-methylcytosine (4mC), an important epigenetic modification formed by the action of sp...

Feb 2019 30052767
The Unreasonable Effectiveness of Convolutional Neural Networks in Population Genetic Inference.

Population-scale genomic data sets have given researchers incredible amounts of information from whi...

Feb 2019 30517664
The role of robotic gait training and tDCS in Friedrich ataxia rehabilitation: A case report.

RATIONALE: Friedrich ataxia (FA) is the most common inherited neurodegenerative cerebellar ataxic sy...

Feb 2019 30813143
EWAS Atlas: a curated knowledgebase of epigenome-wide association studies.

Epigenome-Wide Association Study (EWAS) has become increasingly significant in identifying the assoc...

Jan 2019 30364969
Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB.

Successful development of biological databases requires accommodation of the burgeoning amounts of d...

Jan 2019 30407520
Predicting Influenza A Tropism with End-to-End Learning of Deep Networks.

The type of host that a virus can infect, referred to as host specificity or tropism, influences inf...

Jan 2019 31859569
Computational aspects underlying genome to phenome analysis in plants.

Recent advances in genomics technologies have greatly accelerated the progress in both fundamental p...

Jan 2019 30500991
[Artificial Intelligence for Cancer Genomic Medicine: Understanding Cancer is Beyond Human Ability].

Cancer is a very complex disease that is caused by mutations in genomes and evolves spatiotemporally...

Jan 2019 30630127
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