Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 85-105 of 11,636 articles
Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells.

Circulating tumor cells (CTCs), as pivotal targets in liquid biopsy, offer dynamic, multidimensional...

(6)
Oct 2026 42861255
Spatial transcriptomics elucidates trajectories associated with transformation in malignant peripheral nerve sheath tumors.

BACKGROUND: Tumor invasion and malignant transformation are spatiotemporally coordinated processes t...

(9)
Oct 2026 42858153
Towards data-driven refinement of an automated cluster alert system: assessing the concordance of epidemiological expert assessment and genotyping.

OBJECTIVE: An automated CLuster AleRt system (CLAR) is employed at our hospital to detect clusters o...

(4)
Oct 2026 42858456
Zebrafish behavioral phenomics reveals functional subtypes of autism risk genes.

Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental condition caused by many...

(10)
Oct 2026 42859211
PLEKHA5-targeted photothermal-gene combination therapy via mPDA@DMEA@siRNA nanoparticles suppresses melanoma progression.

Melanoma is an aggressive skin malignancy characterized by high metastatic potential and resistance ...

(5)
Oct 2026 42852675
Prediction From Genomics to Fields: Plant Model Centred Integration for Precision Breeding.

Genotype-to-phenotype (G2P) prediction is the central mission of modern plant breeding. Genomic data...

(7)
Oct 2026 42853032
PROTACs in personalized and precision medicine: transforming targeted therapy with advances in selectivity and patient stratification.

Proteolysis-targeting chimeras (PROTACs) have emerged as a transformative therapeutic strategy that ...

(13)
Oct 2026 42853260
Identification of novel lncRNAs potentially associated with diabetic retinopathy based on machine learning prediction.

OBJECTIVE: Diabetic retinopathy (DR), a neurovascular complication, stands as a major contributor to...

(7)
Oct 2026 42853277
Inferring binding specificities of human transcription factors with the wisdom of crowds.

DNA motif discovery and, particularly, computational modeling of transcription factor binding motifs...

(5)
Oct 2026 42853676
Intraoperative fluorescence spectroscopy for IDH classification in glioma: a feasibility study.

BACKGROUND: Molecular features are fundamental to both the diagnosis and prognosis of gliomas. Speci...

(3)
Oct 2026 42853718
SSL-InsNet: A Sequence Structured Labeling Framework for Large-Scale Genomic Insertion Detection Leveraging Time-Distributed Dual Transformer.

Genomic structural variations (SVs) are pivotal in pathogenesis, yet existing methods often fail to ...

(5)
Oct 2026 42853737
Jian'er Jiedu granule alleviates acute lung injury via NOD2/NF-κB/NLRP3 axis: Network pharmacology, machine learning, and experimental validation.

BACKGROUND: Acute lung injury (ALI) is a severe inflammatory disorder associated with high mortality...

(10)
Oct 2026 42854380
AI-integrated RNA therapeutics in precision oncology.

RNA therapeutics can silence oncogenic transcripts, modulate RNA processing, restore protein express...

(4)
Oct 2026 42854694
Comprehensive Characterization of Bioaerosol Microbial Communities, ARG, and Occupational Exposure Risks in WWTP and Comprehensive Landfill.

In the sewage treatment plant and landfill in the same area, the differences in transmission charact...

(11)
Oct 2026 42854810
Knowledge-guided Multimodal Learning for Interpretable Prediction of Pathological Complete Response and Survival in Breast Cancer.

PURPOSE: Pretreatment estimation of pathological complete response (pCR) to neoadjuvant chemotherapy...

(12)
Oct 2026 42854913
Effects and mechanism of CYBB on the progression of multiple sclerosis: Evidence from bioinformatic analysis and experimental validation.

BACKGROUND: Neutrophil extracellular traps (NETs) are involved in the pathological progression of mu...

(2)
Oct 2026 42855088
Integrative Approaches in Protein Structure/Function Analysis, Design, and Engineering.

Over the past decade, protein design has drawn considerable attention and emerged as a promising too...

(7)
Oct 2026 42850317
Benchmarking ensemble and deep learning models for drought-responsive gene prioritisation in rice using multi-omics data.

Identifying drought-responsive genes is critical for climate-resilient crop breeding, yet computatio...

(4)
Oct 2026 42853794
Beyond the binding site: PROTAC-mediated protein degradation assists the therapeutic paradigm of hematological malignancies.

Hematological malignancies represent a growing global health burden, with conventional therapies lim...

(7)
Oct 2026 42858529
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