Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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pyVIPER: a fast and scalable Python package for protein activity estimation and master regulator analysis of single-cell RNA sequencing data.

Single-cell sequencing has revolutionized biomedical research by offering insights into cellular het...

Jun 2026 42332576
Single-cell RNA sequencing in ovarian cancer: decoding the tumor microenvironment for personalized therapy.

Ovarian cancer (OC) remains a leading cause of mortality among gynecological malignancies, largely d...

Jun 2026 42332817
Decoding the Genetic Architecture of Acute Coronary Syndrome: A Review on Integrated Medical Modeling.

UNLABELLED: Genetic mutations contribute significantly to the complexity of understanding Acute Coro...

Jun 2026 42333850
A modular framework for automated segmentation and analysis of AFM imaging of chromatin organization.

Chromatin organization underlies essential genome functions, but its nanoscale organization remains ...

(1)
Jun 2026 42328787
SpliceSelectNet: a hierarchical Transformer-based deep learning model for splice site prediction.

Accurate RNA splicing is essential for gene expression and protein function, yet the mechanisms gove...

(1)
Jun 2026 42328788
Exploring the genetic landscape of ciprofloxacin-induced DNA supercompaction in Escherichia coli.

DNA-damaging antibiotics like ciprofloxacin (CIP) induce extensive double-strand breaks in Escherich...

(1)
Jun 2026 42328795
Graphylo Var: Predicting the impact of non-coding variants using a multi-species sequence model.

MOTIVATION: Understanding the functional impact of genetic variants is a key problem for precision m...

(2)
Jun 2026 42330352
A blood transcriptomic signature anchored to central nervous system pathology enables noninvasive detection of multiple sclerosis.

BACKGROUND: Multiple sclerosis (MS) lacks noninvasive biomarkers anchored to central nervous system ...

(2)
Jun 2026 42331233
Multi-Omics Analyses Reveal BPA Accelerates Glioma Progression via Cell Cycle Dysregulation.

Bisphenol A (BPA), a pervasive environmental endocrine disruptor, its role in glioma progression is ...

Jun 2026 42331244
DeepGEP: Deep learning for gene expression prediction from multi-omics in mammals.

Deep neural networks offer great potential for integrating multi-omics data to predict gene expressi...

Jun 2026 42331263
Multidimensional Pathogen Fingerprinting via DNA Scaffold-Confined Enzymatic Synthesis of Silicon Quantum Dots.

Accurate and highly sensitive detection of pathogenic bacteria is essential to public health. Conven...

Jun 2026 42331635
Transcriptomic identification of key genes influencing m7G modification in thyroid carcinoma and experimental validation.

BACKGROUND: N7-methylguanosine (m7G) modification plays a critical role in RNA metabolism and is inc...

(1)
Jun 2026 42332284
Predicting piRNA-Disease Associations Based on Dual-View Learning and Multi-head Self-Attention Mechanism Fusion.

PIWI-interacting RNAs (piRNAs) are an important class of non-coding RNA molecules in epigenetic regu...

Jun 2026 42332290
Machine learning-guided risk stratification in elderly AML based on genomic, immunophenotypic and therapeutic profiles.

BACKGROUND: Elderly patients with acute myeloid leukemia (AML) exhibit considerable biological and c...

Jun 2026 42324513
GARN3: A coarse-grained helix centered technique for RNA 3D structures prediction.

The study of predicting three-dimensional structures of RNA (ribonucleic acids) has increased over t...

Jun 2026 42330041
smDeepFLUOR: single-molecule deep learning fluorescence classification.

Fluorescence intensity variation has long served as a primary readout for monitoring biological even...

Jun 2026 42323296
Integrating MRI radiomics and transcriptomics to predict IDH mutation status and prognosis in glioma.

OBJECTIVE: To investigate MRI-based radiomic features in glioma and key genes related to IDH mutatio...

Jun 2026 42324558
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