Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1471-1491 of 11,655 articles
Deep learning of 777 K bulk transcriptomes reveals human-mouse gene conservation beyond DNA sequence similarity.

Mice are widely used as biomedical research models, yet results from mouse gene studies often differ...

May 2026 42204332
A deep mutational scanning-informed protein language model predicts SARS-CoV-2 evolution dynamics with spatiotemporal resolution.

Early identification of emerging dominant variants of pathogens such as SARS-CoV-2 is important for ...

May 2026 42204343
Mutant-Initiated Structure-Guided Refinement Enables Second-Generation Compact IscB Genome Editors.

Compact RNA-guided nucleases such as IscB represent an attractive foundation for next-generation gen...

May 2026 42178964
A neural network model for managing renewable resources with population growth.

This paper presents a fractional-order modelling framework for population-resource dynamics using th...

May 2026 42192135
Current understanding and future directions in severe asthma through artificial intelligence-integrated multi-omic approaches.

Severe asthma remains a challenging, heterogeneous condition, despite significant advances in therap...

(1)
May 2026 42203233
Integrated cell-free DNA and omics genetic scores for early detection of gestational diabetes: evidence from a nationwide multicenter study.

BACKGROUND: Gestational diabetes mellitus (GDM) affects 15.6% of pregnancies globally, with Vietnam ...

May 2026 42186414
Navigating high-order protein fitness landscapes via deep learning on directed evolution trajectories.

Accurately predicting the fitness effects of high-order mutations is a grand challenge in understand...

May 2026 42190010
Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo.

mRNA-based gene editing therapeutics offer the potential to permanently cure diseases but are hinder...

(1)
May 2026 42190011
CWAGS: multi-trait genomic selection using channel weighted attention convolutional network.

BACKGROUND: Genomic selection serves as an effective approach to accelerate the improvement of agron...

May 2026 42192291
Multi-dimensional risk prediction and genetic architecture of aspiration pneumonia: a population-based analysis.

BACKGROUND: Aspiration pneumonia represents a significant but understudied cause of morbidity and mo...

(1)
May 2026 42192339
R-loop-Associated Regulator VDAC1 Drives Malignant Phenotypes in Uveal Melanoma.

BACKGROUND: R-loops regulate genome stability and transcription, but their roles in uveal melanoma (...

May 2026 42203013
Predicting neoadjuvant breast cancer therapy response using BRIDGE from tumor transcriptomics and histopathology.

BACKGROUND: While expression-based signatures inform adjuvant therapy in breast cancer (BC), no appr...

May 2026 42203036
Epigenetic-Metabolic interplay in chronic kidney disease mortality: insights from grimage acceleration and transcriptomic profiling.

BACKGROUND: Chronic kidney disease (CKD) is associated with a substantially elevated risk of mortali...

(1)
May 2026 42186049
From gene discovery to synthetic biology: recent advances in the biosynthesis of oleanane-type pentacyclic triterpenoids.

Covering: 2010 to January 2026Oleanane-type pentacyclic triterpenoids (OPTs) represent a prominent c...

May 2026 42187150
Integrating single-cell analysis and digital pathology for risk stratification in pancreatic cancer.

Early liver metastasis is a major factor contributing to the poor prognosis of pancreatic ductal ade...

May 2026 42189258
Integrative analysis and experimental validation of dioxin-interacting genes reveal diagnostic and prognostic biomarkers in lung adenocarcinoma.

Dioxins are persistent environmental pollutants and key components of the human exposome with establ...

(1)
May 2026 42189270
Integrated transcriptomic analysis identifies liver aging-driven fibrosis signatures and reveals therapeutic strategies based on medicine-food homology.

Despite its strong regenerative capacity, liver aging paradoxically increases susceptibility to fibr...

(7)
May 2026 42191706
Decoding variants of uncertain significance in systemic autoinflammatory diseases.

The development and implementation of genetic testing has revolutionized the diagnostic landscape of...

(1)
May 2026 42191839
Prediction of antimicrobial minimum inhibitory concentration from bacterial genomes using a scalable and interpretable machine learning approach.

Although machine learning models can predict antimicrobial susceptibility from bacterial whole genom...

May 2026 42191912
AI-driven multi-omics drug repurposing nominates AZD7762 as a multitarget inhibitor of IL22RA1 and FAM221A in esophageal squamous cell carcinoma.

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with limited targeted treatmen...

(2)
May 2026 42191940
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