Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Gastric cancer organoids and their convergence in engineering approaches.

Gastric cancer research has rapidly progressed due to interdisciplinary advances in stem cell biolog...

Jan 2026 41532472
Thermophiles in the genomic Era (2015-2025): a review on biodiversity, metagenome-assembled genomes, and future directions.

Thermophile research has been transformed over the past decade by advances in genome sequencing. Onc...

Jan 2026 41532487
Exploring structural diversity and dynamic stability of small-molecule PRMT5 inhibitors through machine learning-based QSAR and molecular modelling.

Protein arginine methyltransferase 5 (PRMT5) is a key epigenetic enzyme that catalyses symmetric arg...

Jan 2026 41533017
Machine learning and multi-omics integration identifies immunological predictors and mechanistic insights in autoimmune encephalitis.

OBJECTIVE: To develop an interpretable prognostic prediction model for autoimmune encephalitis (AE) ...

Jan 2026 41533076
A Boruta-SMOTE Integrated Approach for Rapid Donkey Breed Classification Using SNP Data: Addressing High-Dimensionality and Small Sample Challenges.

With the increasing complexity of genomic data, traditional classification methods face dual challen...

Jan 2026 41533190
Challenges and Opportunities with CRISPR-Based Genome Editing in Legume Crops.

Over the last couple of decades, tremendous progress has been made in legume genomics. Genomics info...

Jan 2026 41533202
Ultrahigh Interfacial Thermal Conductance in Borophene Heterostructures Enabled by the Phonon Bridge.

The rapid integration of nano- and microdevices underscores the critical role of interfacial thermal...

Jan 2026 41533966
Oral-Rinse-Sourced Microbiota in Oral Health and Diseases in a Representative US Adult Population: Implications for Diagnostics.

AIMS: To investigate the associations between oral-rinse microbiota and distinct oral conditions, an...

Jan 2026 41534871
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.

Medullary thyroid carcinoma (MTC) is a rare, aggressive neuroendocrine tumor with limited treatment ...

Jan 2026 41535264
Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing.

Despite the extensive studies of individual RNA modifications, the lack of methods to detect multipl...

Jan 2026 41535294
Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations.

Candida auris, an increasingly prevalent fungal pathogen, requires both rapid identification and ant...

Jan 2026 41535388
IdentifiHR predicts homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression.

BACKGROUND: Approximately half of all high-grade serous ovarian carcinomas (HGSCs) have a therapeuti...

Jan 2026 41535393
Ultra-high-throughput mapping of genetic design space.

Massively parallel genetic screens have been used to map sequence-to-function relationships for a va...

Jan 2026 41535463
Integrating single-cell and bulk transcriptomes with machine learning reveals a CAF signature for immunotherapy response in dMMR endometrial cancer.

BACKGROUND: Cancer-associated fibroblasts (CAFs) are key players in the tumor microenvironment (TME)...

Jan 2026 41535649
Disentangling direct and pleiotropic SNP effects in alfalfa (Medicago sativa L.) using causal graph learning.

Alfalfa (Medicago sativa L.) is a critical forage crop whose improvement depends on resolving the co...

Jan 2026 41535716
FSBLUP: a novel strategy of fusion similarity matrix construction via optimally integrating intermediate omics data to enhance genomic prediction.

The increasing availability of multi-omics data is promising in enhancing genomic prediction in bree...

Jan 2026 41535974
CADS: A Causal Inference Framework for Identifying Essential Genes to Enhance Drug Synergy Prediction.

MOTIVATION: Drug synergy is crucial for developing effective combination therapies, but traditional ...

Jan 2026 41537237
Machine learning reveals sequence and methylation determinants of SaCas9-PAM interactions in bacteria.

Cas9 nucleases defend bacteria against invading DNA and can be used with single guide RNAs (sgRNAs) ...

Jan 2026 41538317
Cutting-Edge AI Technologies in Skin Cancer Applications.

The rapid development of multimodal large language models (LLMs) such as GPT and Med-PaLM is reshapi...

Jan 2026 41544780
Next-generation lung-cancer-on-a-chip: toward personalized therapy, AI, and CRISPR-driven models.

Lung-cancer-on-a-chip (LCOC) technologies have advanced rapidly, yet most models evaluate mechanical...

Jan 2026 41544897
Dbert2_LR: A deep learning-based model for predicting cis-regulatory elements in crops.

Cis-regulatory elements (CREs) are key determinants of gene expression underlying complex agronomic ...

Jan 2026 41544987
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