Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1534-1554 of 11,060 articles
Metabolic-immune interactions in gastric cancer T cells: A single-cell atlas for prognostic biomarker identification.

Metabolic alterations and immune dysfunction within the gastric tumor microenvironment critically dr...

Jan 2026 41675596
UniSplicer: A deep-learning framework for accurate splice-site prediction and splice-altering mutation detection across diverse taxa.

RNA splicing removes non-coding introns from pre-mRNA to generate mature mRNA in eukaryotes, and acc...

Dec 2025 41476368
Neural Latent Filtering for Gene Discovery in Breast Cancer Subtypes.

Gene selection from expression data represents a challenging task, primarily due to the high data di...

Dec 2025 41560779
Optimized primer and model improve precision of X chromosome telomere length determination in the Han population.

The attrition of telomere length is associated with cellular aging and plays a role in multiple age-...

Dec 2025 41623485
Deep-learning/transfer-learning based Overall Survival prediction conditional on Progression-Free Interval with TCGA RNA-seq expression and KEGG-pathways.

We developed a novel deep-learning network that integrated Progression-Free Interval (PFI) as a cond...

Dec 2025 41478194
LEAP: Long sequence enhancer activity analysis and prediction framework.

BACKGROUND AND OBJECTIVE: Enhancer activity is central to the regulation of gene expression. Despite...

Dec 2025 41478195
Improvements to Casanovo, a Deep Learning De Novo Peptide Sequencer.

Casanovo is a state-of-the-art deep learning model for de novo peptide sequencing from mass spectrom...

Dec 2025 41468557
Artificial Intelligence for the Treatment and Management of Colorectal Liver Metastases.

Colorectal cancer (CRC) is the third most commonly diagnosed malignancy worldwide. Prognosis is sign...

Dec 2025 41948161
A machine learning-based model for the prediction of thyroid eye disease with oxidative stress-related biomarkers.

Thyroid eye disease (TED), the most common adult orbital disease, can significantly impair patients'...

Dec 2025 41468804
Machine learning-assisted prognosis of multiple myeloma side population cells via SRGs and OCLR stemness index.

BACKGROUND AND OBJECTIVE: Relapse in Multiple Myeloma, driven by therapy-resistant cancer stem cells...

Dec 2025 41475189
MetaChrome: an open-source, user-friendly tool for automated metaphase chromosome analysis.

DNA Fluorescence In Situ Hybridization (DNA FISH) is an essential technique to study chromosome biol...

Dec 2025 41475630
NAD+ restores proteostasis through splicing-dependent autophagy.

Autophagy preserves neuronal integrity by clearing damaged proteins and organelles, but its efficien...

Dec 2025 41313318
A chalcone-rich extract from licorice root inhibits liver steatosis and fibrosis via regulating PPARα and TGFβ signaling.

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major liver disord...

Dec 2025 41539093
Polyploid giant cancer cells: A novel target in future cancer therapy.

Under intense therapeutic stress-including chemotherapy, radiotherapy, and targeted therapies-tumor ...

Dec 2025 41496179
Morphological regulation of filamentous fungi improves industrial production.

Filamentous fungi have emerged as ideal chassis cells for high-value products such as industrial enz...

Dec 2025 41461244
cncFinder: A graph-attention-network-based interpretable learning model to identify bifunctional long non-coding RNAs.

Certain RNAs exhibit both protein-coding and regulatory non-coding functions, termed bifunctional RN...

Dec 2025 41583561
Causal Inference and Prognostic Modeling in Colorectal Cancer through Integration of Computational Pathology and Mendelian Randomization.

BACKGROUND: While traditional pathology supports the diagnosis and staging of colorectal cancer (CRC...

Dec 2025 41454195
Integrating molecular diagnostics and artificial intelligence in chronic microbial disease.

Chronic microbial diseases, often driven by biofilm formation, pose a persistent global health burde...

Dec 2025 41456738
Graph neural network-based mutation-aware regression test ordering using code dependency graphs and execution traces.

The mutation-aware test prioritisation system in this paper uses Graph Neural Networks (GNNs) to com...

Dec 2025 41551267
PlantscRNAdb 4.0: Improved marker identification and annotation under a cell-type uniformity for plants.

Single-cell RNA sequencing (scRNA-seq) has revolutionized plant biology by enabling high-resolution ...

Dec 2025 41449796
Urinary Tumor DNA to Identify Candidates for Repeat Transurethral Resection in Non-Muscle-Invasive Bladder Cancer.

Repeat transurethral resection of bladder tumor (re-TURBT) is commonly recommended for patients with...

Dec 2025 41445362
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