Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1618-1638 of 11,060 articles
Unveiling CDKN1A and RELA: Machine learning-driven aging biomarkers for precision diagnosis and therapy in knee osteoarthritis.

BACKGROUND: Knee Osteoarthritis (KOA) is a degenerative joint disease marked by progressive cartilag...

Dec 2025 41536554
Pathway-Informed Machine Learning Identifies Genetic Predictors of High-Dose Methotrexate-Induced Mucositis in Pediatric Acute Lymphoblastic Leukemia.

High-dose methotrexate for pediatric cancer treatment is frequently associated with mucositis, which...

Nov 2025 41321063
Impact of disease-modifying therapy on [99mTc]Tc-DPD SPECT/CT markers in transthyretin cardiac amyloidosis enabled by artificial intelligence.

PURPOSE: Transthyretin cardiac amyloidosis (ATTR-CM) is a progressive, underdiagnosed disease with h...

Nov 2025 41317182
Integrating pan-genome analysis, GWAS, and interpretable machine learning to prioritize trait-associated structural variations in Setaria italica.

Structural variations (SVs), especially presence-absence variations (PAVs), are crucial in crop dome...

Nov 2025 41319002
Engineering lignin pathway, plant cell wall modification, and genome editing for advanced renewable bioenergy and material applications.

Lignin biosynthesis and plant cell wall engineering are central to plant structural integrity and bi...

Nov 2025 41325824
Viral traits from deep mutational scanning and socio-demographic context predict SARS-CoV-2 lineage fitness across diverse countries.

OBJECTIVES: To assess the joint effects of SARS-CoV-2 viral traits (ACE2 binding, immune escape, and...

Nov 2025 41319790
An Explainable Deep Model for Risk Scoring and Accurate Radionecrosis Identification Following Brain Metastasis Stereotactic Radiosurgery.

PURPOSE: As survival improves for patients with brain metastases (BM), distinguishing local recurren...

Nov 2025 41317799
High-throughput sequencing reveals microbial transitions in refrigerated sturgeon meat: Implications for quality assurance.

This study investigated the microbially driven spoilage mechanism of sturgeon (Acipenser baerii) und...

Nov 2025 41389787
EIOFX-DT: Leveraging graph centrality metrics for feature extraction and classification of viral genetic sequences.

Many diseases have a genetic origin, and analyzing intracellular structures through genetic data yie...

Nov 2025 41488416
Nanopore-Based Label-Free and Single-Molecule Sequencing toward Precision Diagnosis.

Nanopore-based single-molecule sequencing (SMS) is a powerful tool for acquiring detailed heterogene...

Nov 2025 41307290
Diagnosis of head and neck cancer by AI-based tumor-educated platelet RNA profiling of liquid biopsies.

Over 95% of head and neck cancers are squamous cell carcinoma (HNSCC). HNSCC is mostly diagnosed lat...

Nov 2025 41307954
DeepHFFT-m7G: A dual-channel self-attention and hybrid feature fusion framework for RNA m7G modification identification.

N7-Methylguanosine (m7G) is a prevalent RNA modification that has attracted significant attention in...

Nov 2025 41314160
Advances in antituberculosis drug-induced liver injury: Molecular mechanisms, genetic insights, and emerging animal-free prediction models.

Approximately 10 million tuberculosis patients worldwide require drug therapies annually. However, p...

Nov 2025 41314589
Hereditary syndromes and RCC: what radiologists need to know.

Hereditary renal cell carcinoma (RCC) accounts for approximately 5-8% of all renal cancers. This rev...

Nov 2025 41284030
Functional profiling of the chaperone systems interactome in breast cancer using experimental and machine-learning data.

Breast cancer heterogeneity stems from diverse molecular alterations, including proteostasis loss du...

Nov 2025 41308292
Identification of common genetic features and pathways for osteoporosis with frozen shoulder by integrated bioinformatics analysis and machine learning.

Frozen shoulder (FS) and osteoporosis (OP) are common age-related degenerative diseases, occurring m...

Nov 2025 41276899
GCLM as a novel biomarker for preeclampsia: Integrating bioinformatics and mechanistic validation.

INTRODUCTION: Preeclampsia (PE) is a pregnancy-specific disorder associated with hypertension and mu...

Nov 2025 41380586
Guiding design and performance of nonviral nucleic acid delivery vehicles via machine learning.

Machine Learning (ML) techniques have enabled the advancement of many technologies throughout the ph...

Nov 2025 41297827
Regulatory mechanism of the oprM gene in colistin resistance of acinetobacter baumannii.

BACKGROUND: Colistin resistance in Acinetobacter baumannii (AB) is a serious clinical concern. This ...

Nov 2025 41308409
Autocatalytic Circular DNA Powered Plasmonic CRISPR/Cas12a Platform for Ultrasensitive Non-Nucleic Acid Target Sensing.

CRISPR/Cas12a-based detection of non-nucleic acid targets faces two major challenges: 1) limited sen...

Nov 2025 41287270
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