Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1618-1638 of 11,655 articles
Enhancing Drug Response Prediction in Epilepsy with Emerging Multimodal Models: Focus on Clinical, Pharmacologic, and Genomic Factors.

Epilepsy is a common neurological disorder, with approximately one-third of the affected population ...

May 2026 42143205
Prognostic Significance and Therapeutic Implications of Migrasome-related genes in Sorafenib Treatment for Primary Liver Cancer.

PURPOSE: This study aimed to reveal the mechanism and prognostic significance of migrasome-related g...

May 2026 42144083
Conserved hydrophobic gatekeeper mechanisms in COX-1-like pockets revealed by AI-driven pocket similarity and molecular dynamics simulations of mofezolac.

Cyclooxygenase-1 (COX-1, PTGS1) has recently re-emerged as a significant therapeutic target in infla...

May 2026 42160909
Identification of diagnostic senescence-associated marker genes in asthma based on machine learning and experimental validation.

BACKGROUND AND AIMS: Asthma imposes a significant global health burden; however, the mechanistic rol...

(1)
May 2026 42161063
Stable maintenance of MERVL-positive embryonic stem cells reveals sustained transcriptional programs and enhancer remodeling.

Mouse embryonic stem cells (ESCs) occasionally transit into a rare two-cell-like (2C) state characte...

May 2026 42142582
Cross-Platform Comparative Spatial Transcriptomics in High-Grade Serous Carcinoma.

PURPOSE: High-grade serous carcinoma (HGSC) is a remarkably heterogeneous tumor. The purpose of this...

May 2026 42142589
The role of whole genome sequencing in antimicrobial susceptibility prediction of bacteria: 2025 update from the EUCAST Subcommittee.

SCOPE: The 2017 European Committee on Antimicrobial Susceptibility Testing (EUCAST) subcommittee rep...

(1)
May 2026 42142806
Artificial intelligence in the differential diagnosis of hypertrophic cardiomyopathy and physiological hypertrophy: a scoping review.

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common inherited myocardial disorder and a...

May 2026 42142808
Predicting gene-specific regulation with transcriptomic and epigenetic single-cell data.

MOTIVATION: Analysis of single cell ATAC-seq and RNA-seq data has allowed to gain unprecedented insi...

May 2026 42143610
PythiaStudio: a one-stop protein engineering platform powered by Pythia model suite.

Predicting how mutations affect protein stability and protein-protein binding affinity is crucial fo...

(1)
May 2026 42136527
NucVerse3D: generalizable 3D nuclear instance segmentation across heterogeneous microscopy modalities.

Accurate three-dimensional (3D) nuclear instance segmentation is a prerequisite for quantitative phe...

May 2026 42141034
Network clustering algorithms and preprocessing pipelines for robust cell type identification in single-cell RNA sequencing data.

Single cell RNA-seq (scRNA-seq) technologies provide unprecedented resolution representing transcrip...

May 2026 42141063
Osteoarthritis phenotypes: advancing precision medicine through clinical, structural, and molecular stratification.

PURPOSE: Osteoarthritis (OA) is now understood as a heterogeneous syndrome driven by diverse biologi...

(1)
May 2026 42141125
HESpotEx: a dual-stream deep learning framework for spot-level gene expression prediction from histological images.

Whole-slide histopathological images (WSIs) constitute a fundamental approach in disease diagnosis a...

May 2026 42141326
Metabolomics at the Crossroads of Forensic Toxicology and Precision Diagnostics: Analytical Innovations and Translational Opportunities.

Metabolomics is the comprehensive analysis of small-molecule metabolites in living systems and is in...

May 2026 42141372
Sequence determinant and functional relevance of 8-oxoguanine RNA modification unveiled from foundation-model-based predictor.

8-Oxoguanine (o8G) is an oxidative RNA modification that plays critical roles in cellular processes ...

May 2026 42293252
Identification and validation of lactylation-related genes signature and immune infiltration landscape of rheumatoid arthritis based on machine learning.

BACKGROUND: The pathogenic mechanisms underlying rheumatoid arthritis (RA) remain elusive. Lactylati...

May 2026 42135859
Crotonylation: A Novel Layer of the Epigenetic Landscape in Disease.

Crotonylation is a lysine acylation modification that links cellular metabolism to epigenetic regula...

May 2026 42140345
Stability of nanosuspensions in drug delivery: mechanisms, characterization strategies, and advanced stabilization approaches.

Poorly soluble drug delivery is a long-standing core challenge in the pharmaceutical field. With a d...

May 2026 42140400
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