Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Mapping the Conformational Landscape of DNA Minicircles Through Atomic Force Microscopy and Shape Space Analysis.

The structural dynamics of DNA underpin essential biological processes, yet conventional structural ...

May 2026 42132089
Robust CRISPR-Cas Protein Identification using Max-Margin Regularized Transformer Models.

The discovery of CRISPR-Cas system has significantly advanced genome editing, offering vast applicat...

May 2026 42133523
Machine learning-guided risk stratification for Long QT Syndrome genetic variants with hiPSC-derived cardiomyocytes.

AIMS: Long QT syndrome (LQTS) is a life-threatening genetic disorder characterized by prolonged QT i...

May 2026 42133816
Understanding Cell Wall Enzyme Function: From Classical Approaches to New Biotechnology.

Plant cell walls are complex networks of polysaccharides that underpin plant structure and provide d...

May 2026 42135035
Large-scale data-driven pre-trained DNA models enhance performance across diverse genomics tasks.

Sequence-based deep learning has advanced genome interpretation, yet most models remain task-specifi...

May 2026 42135287
AI-powered and manual assessment of tumor-infiltrating lymphocytes in early HER2-positive breast cancer in NSABP B-41.

The assessment of tumor-infiltrating lymphocyte (TILs), together with gene expression signatures (GE...

(3)
May 2026 42135347
Concepts of RNA virus evolution for the design of better antiviral countermeasures.

This century, global human health has been marked by a seemingly increasing list of outbreaks and ep...

May 2026 42135467
How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.

The number of possible variants representing the landscape of a protein sequence of length N residue...

May 2026 42132839
Non-Invasive Screening of AI-Assisted DNA Aneuploidy Cytology by Image Cytometry for the Early Diagnosis of Malignant Transformation of OPMDs.

INTRODUCTION AND AIMS: Oral exfoliative DNA aneuploidy cytology by image cytometry (DNA-ICM) has bee...

May 2026 42134189
Maternal genetic variants associated with aneuploid conception: a narrative review.

BACKGROUND: Human aneuploid conception, a leading cause of infertility, pregnancy loss, and congenit...

May 2026 42124334
Machine Learning-Assisted Portable Ai BOX Based on RPA-CRISPR/Cas12a for Rapid On-Site Detection of Foodborne Pathogens.

Foodborne pathogens present a major threat to global public health. However, conventional detection ...

(1)
May 2026 42126246
Revisiting the Molecular Roadmap for Sugar Crops: Genome Reading, Trait Writing and Variety Redesigning.

Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major...

May 2026 42126266
Comparison between a conventional tool and deep learning models for RNA velocity analysis of scRNA-Seq data.

Single-cell RNA sequencing (scRNA-Seq) enables analysis of gene expression at single-cell resolution...

May 2026 42126634
Sensory nerves protect against preclinical tendinopathic changes through FGF1 signaling.

Chronic tendinopathy is typified by persistent tendon-associated pain, transmitted by local nocicept...

May 2026 42127222
Semen RNA-Based Biomarkers for Prostate Cancer Detection and Risk Stratification: A Prospective Multi-Center Validation Study.

OBJECTIVE: To assess the diagnostic performance of semen RNA-based biomarkers for detecting prostate...

(2)
May 2026 42127322
Recent Advances in the Development of CRISPR-Based Live-Cell Molecular Imaging and Sensing.

Visualizing genome organization and transcriptional dynamics with spatial and temporal precision in ...

May 2026 42128985
Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD.

Despite the power of CRISPR in genome editing, its clinical application is limited by off-target eff...

May 2026 42129132
Integrating scanning electron microscopy, explainable deep learning, and ITS sequencing for accurate identification in some species Geastrum.

The differentiation of species within the genus Geastrum remains a challenging task due to the stron...

May 2026 42129448
Estimating genotype-tissue specific gene expression using hybrid deep learning.

Genotype-tissue expression profiles are critical for understanding how genetic variation influences ...

May 2026 42129502
Integrative bioinformatic analysis prioritizes TIMP1 and FN1 as angiogenesis-related candidate genes in diabetic foot ulcers.

BACKGROUND: Diabetic foot ulcers (DFUs) represent a severe chronic complication of diabetes and are ...

May 2026 42127081
Glycolytic reprogramming in host response to Borrelia burgdorferi: A gene signature revealed by integrative bioinformatics analysis and machine learning.

Lyme disease (LD), a multifaceted condition caused by Borrelia burgdorferi (Bb), remains poorly unde...

May 2026 42199349
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