Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1744-1764 of 11,076 articles
Identification and Verification of SLC6A15 Involved in Keloid via Bioinformatics Analysis and Machine Learning.

Keloid is a fibroproliferative disorder that poses a challenge in clinical management. This study ai...

Jul 2025 40742424
Global genomics of Lactococcus lactis: horizontal gene transfer and intergenic variation drive multiple domestication and dairy adaptation.

INTRODUCTION: Lactococcus lactis is a crucial lactic acid bacterium of great economically significan...

Jul 2025 40749792
Genetic predisposition to unwanted side effects under antidepressants and antipsychotics: a molecular-genetic study of 902 patients over 6 weeks.

This project aimed at (1) detailing the complex side effect patterns of 902 inpatients treated for m...

Jul 2025 40719850
Biomarkers associated with Hashimoto's thyroiditis induced by viral infection: An integrative bioinformatics and machine learning.

OBJECTIVE: Hashimoto's thyroiditis (HT) is a common disease characterized by autoimmune injury of th...

Jul 2025 42089095
A machine learning platform for genotype-specific cardiotoxicity risk prediction using patient-derived iPSC-CMs.

INTRODUCTION: Drug-induced Torsades de Pointes (TdP) has led to withdrawal of several drugs from the...

Jul 2025 40706985
Emerging innovations in ophthalmic drug delivery for diabetic retinopathy: a translational perspective.

Diabetic retinopathy (DR) is a progressive microvascular complication of diabetes and a leading caus...

Jul 2025 40685494
AI Prognostication in Nonsmall Cell Lung Cancer: A Systematic Review.

The systematic literature review was performed on the use of artificial intelligence (AI) algorithms...

Jul 2025 40679809
Search for Specific Inhibitors Targeting Type IA Topoisomerases.

The type IA topoisomerase subfamily includes bacterial topoisomerase I and topoisomerase III encoded...

Jul 2025 40680817
Diagnostic technologies for neuroblastoma.

Neuroblastoma is an aggressive childhood cancer characterised by high relapse rates and heterogenici...

Jul 2025 40653949
Tuning antibody stability and function by rational designs of framework mutations.

Artificial intelligence and machine learning models have been developed to engineer antibodies for s...

Jul 2025 40653772
Integrating bulk and single-cell RNA sequencing reveals intratumor heterogeneity phenotypes and immune infiltration in pancreatic cancer.

BACKGROUND: Although the significance of intratumoral heterogeneity (ITH) has been widely acknowledg...

Jul 2025 40652419
B4GALT3 as a Key Glycosyltransferase Gene in Multiple Myeloma Progression: Insights From Bioinformatics, Machine Learning, and Experimental Validation.

Glycosylation abnormalities are critical in the progression of various cancers. However, their role ...

Jul 2025 40652559
Machine learning-based preoperative prediction of mutation status in adult gliomas using clinical features.

BACKGROUND: As isocitrate dehydrogenase (IDH) mutation status represents a critical prognostic facto...

Jul 2025 40653372
A comprehensive analysis of transcription factors identified TCF3 as a prognostic target for glioma.

Transcription factors (TFs) are pivotal in tumor initiation and progression, regulating downstream g...

Jul 2025 40653505
Machine learning modeling and analysis of prognostic hub genes in cervical adenocarcinoma: a multi target therapy for enhancement in immunosurveillance.

Endocervical adenocarcinoma (ECA) the fatal and intrusive subtype of cervical carcinoma is on rise f...

Jul 2025 40653567
Modification and applications of glucose oxidase: optimization strategies and high-throughput screening technologies.

Glucose oxidase (GOD), an oxidoreductase (EC 1.1.3.4), catalyzes the oxidation of β-D-glucose to glu...

Jul 2025 40650823
Development and validation of a prognostic model for predicting survival and immunotherapy benefits in melanoma based on metabolism-relevant genes.

Skin cutaneous melanoma (SKCM) is a fatal form of skin cancer. Metabolism-related genes (MRGs) compr...

Jul 2025 40652057
Identification and validation of epithelial‑mesenchymal transition‑related genes for diabetic nephropathy by WGCNA and machine learning.

Diabetic nephropathy (DN) is the main cause of end‑stage renal disease, with epithelial‑mesenchymal ...

Jul 2025 40641111
Machine learning-selected minimal features drive high-accuracy rule-based antibiotic susceptibility predictions for via metagenomic sequencing.

Antimicrobial resistance (AMR) represents a critical global health challenge, demanding rapid and ac...

Jul 2025 40642980
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