Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Optimizing Rare Disease Gait Classification through Data Balancing and Generative AI: Insights from Hereditary Cerebellar Ataxia.

The interpretability of gait analysis studies in people with rare diseases, such as those with prima...

SOFB is a comprehensive ensemble deep learning approach for elucidating and characterizing protein-nucleic-acid-binding residues.

Proteins and nucleic-acids are essential components of living organisms that interact in critical ce...

Multi-Instance Multi-Task Learning for Joint Clinical Outcome and Genomic Profile Predictions From the Histopathological Images.

With the remarkable success of digital histopathology and the deep learning technology, many whole-s...

GMILT: A Novel Transformer Network That Can Noninvasively Predict EGFR Mutation Status.

Noninvasively and accurately predicting the epidermal growth factor receptor (EGFR) mutation status ...

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RNA-dependent liquid-liquid phase separation (LLPS) proteins play critical roles in cellular process...

A miRNA-based epigenetic molecular clock for biological skin-age prediction.

Skin aging is one of the visible characteristics of the aging process in humans. In recent years, di...

SIMS: A deep-learning label transfer tool for single-cell RNA sequencing analysis.

Cell atlases serve as vital references for automating cell labeling in new samples, yet existing cla...

Precision Basecalling of Single DNA Nucleotide from Overlapped Transmission Readouts with Machine Learning Aided Solid-State Nanogap.

DNA sequencing with the quantum tunneling technique heralds a paradigm shift in genetic analysis, pr...

Autonomous assembly and disassembly of gliding molecular robots regulated by a DNA-based molecular controller.

In recent years, there has been a growing interest in engineering dynamic and autonomous systems wit...

Identification of drug responsive enhancers by predicting chromatin accessibility change from perturbed gene expression profiles.

Individual may response to drug treatment differently due to their genetic variants located in enhan...

Machine learning models for predicting blood pressure phenotypes by combining multiple polygenic risk scores.

We construct non-linear machine learning (ML) prediction models for systolic and diastolic blood pre...

Machine learning-derived immunosenescence index for predicting outcome and drug sensitivity in patients with skin cutaneous melanoma.

The functions of immunosenescence are closely related to skin cutaneous melanoma (SKCM). The aim of ...

Determinants of Chromatin Organization in Aging and Cancer-Emerging Opportunities for Epigenetic Therapies and AI Technology.

This review article critically examines the pivotal role of chromatin organization in gene regulatio...

Identification of Marker Genes in Infectious Diseases from ScRNA-seq Data Using Interpretable Machine Learning.

A common result of infection is an abnormal immune response, which may be detrimental to the host. T...

Machine learning-based identification and immune characterization of ferroptosis-related molecular clusters in osteoarthritis and validation.

Osteoarthritis (OA), a degenerative joint disease, involves synovial inflammation, subchondral bone ...

Growth period determination and color coordinates visual analysis of tomato using hyperspectral imaging technology.

Growth period determination and color coordinates prediction are essential for comparing postharvest...

Unveiling MiRNA-124 as a biomarker in hypertrophic cardiomyopathy: An innovative approach using machine learning and intelligent data analysis.

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a widespread hereditary cardiac pathology character...

On knowing a gene: A distributional hypothesis of gene function.

As words can have multiple meanings that depend on sentence context, genes can have various function...

GEMA: A Genome Exact Mapping Accelerator Based on Learned Indexes.

In this article, we introduce GEMA, a genome exact mapping accelerator based on learned indexes, spe...

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