Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1828-1848 of 11,076 articles
Uncovering key markers and therapeutic targets for renal fibrosis in diabetic kidney disease through bulk and single-cell RNA sequencing.

BACKGROUND: Diabetic kidney disease (DKD) is the major cause of chronic kidney failure, with tubuloi...

Jul 2025 40615901
Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data.

BACKGROUND: Oxidative stress plays a crucial role in the development of diabetic foot ulcers (DFU). ...

Jul 2025 40616164
Precise metabolic dependencies of cancer through deep learning and validations.

Cancer cells exhibit metabolic reprogramming to sustain proliferation, creating metabolic vulnerabil...

Jul 2025 40616842
MPNN-CWExplainer: An enhanced deep learning framework for HIV drug bioactivity prediction with class-weighted loss and explainability.

AIMS: Human Immunodeficiency Virus (HIV) remains a critical global health concern due to its impact ...

Jul 2025 40617525
Deep Learning Discovers New Morphological Features while Predicting Genetic Alterations from Histopathology of Papillary Thyroid Carcinoma.

Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the endocrine system. muta...

Jul 2025 40607934
Identification of proliferating neural progenitors in the adult human hippocampus.

Continuous adult hippocampal neurogenesis is involved in memory formation and mood regulation but is...

Jul 2025 40608919
Direct Modeling of DNA and RNA Aptamers with AlphaFold 3: A Promising Tool for Predicting Aptamer Structures and Aptamer-Target Interactions.

Aptamers, single-stranded nucleic acids that fold into unique three-dimensional shapes, bind selecti...

Jul 2025 40610378
Exploring the impact of neutrophils on lung adenocarcinoma using Mendelian randomization and transcriptomic study.

Tumor immune microenvironment plays a crucial role in determining the prognosis of lung adenocarcino...

Jul 2025 40610605
Machine learning-based identification of wastewater treatment plant-specific microbial indicators using 16S rRNA gene sequencing.

Effluent released from municipal wastewater treatment plants reflects the microbial communities resp...

Jul 2025 40610607
Predicting RNA Structure Utilizing Attention from Pretrained Language Models.

RNA possesses functional significance that extends beyond the transport of genetic information. The ...

Jul 2025 40601389
Genetic features for drug responses in cancer - Investigating an ensemble-feature-selection approach.

Predicting drug responses using genetic and transcriptomic features is crucial for enhancing persona...

Jul 2025 40609290
Integrative multi-omics analysis reveals BEST1 as a potential tumor-associated gene in gliomas.

BACKGROUND: The newest glioma classification in WHO 2021 emphasizes the importance of gene mutations...

Jul 2025 40614923
Smart-Plexer 2.0: Leveraging New Features of Amplification Curves to Enhance the Selection of Multiplex PCR Assays in Multi-Target Identification.

Multiplex PCR plays a critical role in diagnostics by enabling the detection of multiple targets in ...

Jul 2025 40600355
Deep learning-enhanced development of innovative antioxidant liposomal drug delivery systems from natural herbs.

Free radical-mediated oxidative damage to biological macromolecules, such as DNA and proteins, signi...

Jul 2025 40600624
Leveraging protein language models for cross-variant CRISPR/Cas9 sgRNA activity prediction.

MOTIVATION: Accurate prediction of single-guide RNA (sgRNA) activity is crucial for optimizing the C...

Jul 2025 40600900
Deep learning deciphers the related role of master regulators and G-quadruplexes in tissue specification.

G-quadruplexes (GQs) are non-canonical DNA structures encoded by G-flipons with potential roles in g...

Jul 2025 40603503
DCAF13 Regulates Cell Proliferation and Immune Escape of Hepatocellular Carcinoma Through Activating the NF-κB Pathway.

Hepatocellular carcinoma (HCC), the third leading cause of global cancer deaths, has a high unmet cl...

Jul 2025 40603761
False-positive tolerant model misconduct mitigation in distributed federated learning on electronic health record data across clinical institutions.

As collaborative Machine Learning on cross-institutional, fully distributed networks become an impor...

Jul 2025 40603924
Cohesive data analysis for the identification of prognostic hub genes and significant pathways associated with HER2 + and TN breast cancer types.

Breast cancer is the most prevalent and lethal form of cancer being the utmost common medical concer...

Jul 2025 40604083
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