Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 1975-1995 of 11,655 articles
Genomic Determinants of Response to Alpelisib Plus Fulvestrant in the SOLAR-1 Trial.

BACKGROUND: Approximately 40% of patients with hormone receptor-positive (HR+), human epidermal grow...

Apr 2026 41967638
Identifying mitochondria-related signatures for tuberculosis diagnosis through machine learning on single-cell transcriptomics data and experimental verification.

Tuberculosis (TB) remains a major cause of infectious disease mortality. Early diagnosis is crucial ...

(1)
Apr 2026 41967724
Accelerated long-read variant calling with Clair3 for whole-genome sequencing.

SUMMARY: The rapid growth of genomic data and increasing adoption of long-read sequencing technologi...

Apr 2026 41967838
Regulatory B cells and SIVA1-LAG3 immune suppression predict poor prognosis in prostate cancer.

Prostate cancer (PCa) is among the most prevalent malignancies affecting men globally. The immunosup...

(1)
Apr 2026 41960835
Differentiating long QT syndrome genotypes using electrocardiographic geometric parameterization and machine learning approaches.

Long QT Syndrome (LQTS) is an inherited cardiac disorder characterized by dysfunctional cardiac ion ...

Apr 2026 41961050
Predictive bioactivity modeling and structural binding analysis for the identification of potential SMYD3 modulators.

SMYD3 is a lysine methyltransferase involved in epigenetic regulation and oncogenic transcription, m...

Apr 2026 41961390
Deep Learning-Enabled Multimodal AFM Image Enhancement: Correlation Analysis between Surface Topography and Multiphysics Fields.

In materials science, performing a synchronous correlative analysis of multiphysics fields at the na...

Apr 2026 41961746
Tripleknock: predicting lethal effect of three-gene knockout in bacteria by deep learning.

Investigating the lethal effect of multi-gene knockout is essential for discovering novel antibiotic...

Apr 2026 41963398
Enhanced Quantitative Phosphocreatine MR Imaging of Skeletal Muscle Using a Global-Local Two-Branch Deep Learning Model.

PURPOSE: Phosphocreatine (PCr) is an essential marker of muscle metabolism, and accurate quantificat...

Apr 2026 41964083
Smart diagnostics: Leveraging artificial intelligence for accurate at-home COVID-19 testing.

Reverse transcriptase polymerase chain reaction (RT-PCR), the reference standard for COVID-19 diagno...

Apr 2026 42000671
Predicting sediment ecological state from metagenomes shows equal performance for taxonomic and functional features.

The use of environmental microbial DNA to monitor the ecological state in seafloor sediments has man...

Apr 2026 42000556
scAClc: A Multi-Objective Adaptive Clustering Framework for Single-Cell Transcriptomics via Contrastive and Resolution-Aware Representation Learning.

Single-cell RNA sequencing (scRNA-seq) enables whole-transcriptomic profiling at single-cell resolut...

Apr 2026 41955402
Integrating metagenomics into legume breeding: A breeder-centered roadmap from core microbiomes to precision inoculation.

Metagenomics, culture-independent profiling of genetic material recovered from environmental samples...

Apr 2026 41966291
HeFS: Helper-Enhanced Feature Selection via Pareto-Optimized Genetic Search.

INTRODUCTION: Feature selection plays a crucial role in improving predictive performance and interpr...

Apr 2026 41966478
Investigating the potential risk of nicotine exposure on glioblastoma: Integrating Mendelian randomization and network toxicology analysis.

OBJECTIVE: To investigate the potential risk of nicotine exposure on glioblastoma multiforme (GBM). ...

(1)
Apr 2026 41967427
Improved tumor-only variant calling and mutation burden estimation with VarNet-T.

Somatic variant calling algorithms typically detect mutations in cancer genomes by comparing sequenc...

Apr 2026 41957035
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