Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 2059-2079 of 11,076 articles
Mechanistic exploration of hexokinase 2 and metabolism in diabetic cardiomyopathy.

The pathogenesis of diabetic cardiomyopathy (DCM) remains incompletely understood. The present study...

May 2025 40417885
Heterophily-Aware Representation Learning on Heterogeneous Graphs.

Real-world graphs are typically complex, exhibiting heterogeneity in the global structure, as well a...

May 2025 40418598
TaxaCal: enhancing species-level profiling accuracy of 16S amplicon data.

BACKGROUND: 16S rRNA amplicon sequencing is a widely used method for microbiome composition analysis...

May 2025 40419960
The development of predictive biomarkers and immunologic markers for breast cancer: current status and future perspectives.

Breast cancer is the leading cause of cancer-related mortality among women worldwide. The developmen...

May 2025 40435086
Extrachromosomal circular DNA drives dynamic genome plasticity: emerging roles in disease progression and clinical potential.

Extrachromosomal circular DNA (eccDNA) has emerged as a dynamic and versatile genomic element with k...

May 2025 40521196
deepTFBS: Improving within- and Cross-Species Prediction of Transcription Factor Binding Using Deep Multi-Task and Transfer Learning.

The precise prediction of transcription factor binding sites (TFBSs) is crucial in understanding gen...

May 2025 40411397
Deep learning algorithms reveal genomic markers for anxiety disorder in a large cohort of children with down syndrome.

Despite a significant burden of neurobehavioral and psychiatric comorbidities in children with Down ...

May 2025 40413309
Integrative multi-omics reveal NSUN2 facilitates glycolysis and histone lactylation-driven immune evasion in renal carcinoma.

Clear cell renal carcinoma (ccRCC) is the most prevalent and aggressive subtype of kidney cancer. Ta...

May 2025 40413354
Role of machine learning in molecular pathology for breast cancer: A review on gene expression profiling and RNA sequencing application.

INTRODUCTION: Breast cancer is the most prevalent cancer among women, with growing incidence and mor...

May 2025 40419230
Role of artificial intelligence in cancer drug discovery and development.

The role of artificial intelligence (AI) in cancer drug discovery and development has garnered signi...

May 2025 40414522
Extended Linear Confined Zipper Cascaded Reaction for Highly Efficient Intracellular Imaging and Assisting Diagnosis of Thyroid Cancer.

Highly sensitive detection and in situ tracing analysis of small-molecule biomarkers are particularl...

May 2025 40405610
POCALI: Prediction and Insight on CAncer LncRNAs by Integrating Multi-Omics Data with Machine Learning.

Long non-coding RNAs (lncRNAs) are receiving increasing attention as biomarkers for cancer diagnosis...

May 2025 40405764
Construction and Multi-dimensional Validation of a Lactylation-Related Signature for Glioblastoma Multiforme Prognostic and Therapeutic Purposes.

Glioblastoma multiforme, one of the most malignant types of brain tumor, heavily relies on glycolyti...

May 2025 40407859
Mechanisms underlying obesity-malignancy connection: a systematic narrative review.

The association between obesity and cancer risk carries substantial public health ramifications as o...

May 2025 40408050
Deconstructing the GWAS library - Next Generation GWAS.

Genome-wide association studies (GWAS) have identified numerous common genetic variants associated w...

May 2025 40408169
Single-cell multimodal analysis reveals tumor microenvironment predictive of treatment response in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) constitutes over 80% of lung cancer cases and remains a leading c...

May 2025 40408481
Biallelic loss-of-function variants in ZNF142 are associated with a robust DNA methylation signature affecting a limited number of genomic loci.

Biallelic inactivating variants in ZNF142 underlie a clinically variable neurodevelopmental disorder...

May 2025 40410387
A standardized framework for robust fragmentomic feature extraction from cell-free DNA sequencing data.

Fragmentomics features of cell-free DNA represent promising non-invasive biomarkers for cancer diagn...

May 2025 40410787
Integrating Knowledge: The Power of Ontologies in Psychiatric Research and Clinical Informatics.

Ontologies are structured frameworks for representing knowledge by systematically defining concepts,...

May 2025 40414449
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