Geriatrics

A Combined One-Class SVM and Template-Matching Approach for User-Aided Human Fall Detection by Means of Floor Acoustic Features.

The primary cause of injury-related death for the elders is represented by falls. The scientific community devoted them particular attention, since injuries can be limited by an early detection of the event. The solution proposed in this paper is based on a combined One-Class SVM (OCSVM) and template-matching classifier that discriminate human falls from nonfalls in a semisupervised framework. Aco...

Continuous detection of human fall using multimodal features from Kinect sensors in scalable environment.

BACKGROUND AND OBJECTIVES: Automatic detection of human fall is a key problem in video surveillance and home monitoring. Existing methods using unimodal data (RGB / depth / skeleton) may suffer from the drawbacks of inadequate lighting condition or unreliability. Besides, most of proposed methods are constrained to a small space with off-line video stream.

BrainAGE score indicates accelerated brain aging in schizophrenia, but not bipolar disorder.

BrainAGE (brain age gap estimation) is a novel morphometric parameter providing a univariate score derived from multivariate voxel-wise analyses. It u...

Quad-phased data mining modeling for dementia diagnosis.

BACKGROUND: The number of people with dementia is increasing along with people's ageing trend worldwide. Therefore, there are various researches to im...

Performance of Machine Learning Algorithms for Qualitative and Quantitative Prediction Drug Blockade of hERG1 channel.

Drug-induced abnormal heart rhythm known as (TdP) is a potential lethal ventricular tachycardia found in many patients. Even newly released anti-arrh...

A novel method for designing and optimizing the layout of facilities in bathroom for the elderly in home-based rehabilitation.

PURPOSE: The home-based rehabilitation of elderly patients improves their autonomy, independence and reintegration into society. Hence, a suitable env...

Using short-range and long-range functional connectivity to identify schizophrenia with a family-based case-control design.

Abnormal short-range and long-range functional connectivities (FCs) have been implicated in the neurophysiology of schizophrenia. This study was condu...

An In-home Advanced Robotic System to Manage Elderly Home-care Patients' Medications: A Pilot Safety and Usability Study.

PURPOSE: We examined the safety profile and usability of an integrated advanced robotic device and telecare system to promote medication adherence for...

A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages.

Neuroimaging has made it possible to measure pathological brain changes associated with Alzheimer's disease (AD) in vivo. Over the past decade, these ...

Automated detection of pathologic white matter alterations in Alzheimer's disease using combined diffusivity and kurtosis method.

Diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) are important diffusion MRI techniques for detecting microstructure abnormities in...

DES-ncRNA: A knowledgebase for exploring information about human micro and long noncoding RNAs based on literature-mining.

Noncoding RNAs (ncRNAs), particularly microRNAs (miRNAs) and long ncRNAs (lncRNAs), are important players in diseases and emerge as novel drug targets...

Protective effect of Nelumbo nucifera extracts on beta amyloid protein induced apoptosis in PC12 cells, in vitro model of Alzheimer's disease.

Alzheimer's disease (AD) is the most common cause of dementia in the elderly. β-Amyloid (Aβ) has been proposed to play a role in the pathogenesis of A...

Case report of a novel mutation of the gene in a patient with branchio-oto-renal syndrome.

Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by the coexistence of branchial cysts or fistulae, external ear malf...

Aging, frailty and complex networks.

When people age their mortality rate increases exponentially, following Gompertz's law. Even so, individuals do not die from old age. Instead, they ac...

DeepNAT: Deep convolutional neural network for segmenting neuroanatomy.

We introduce DeepNAT, a 3D Deep convolutional neural network for the automatic segmentation of NeuroAnaTomy in T1-weighted magnetic resonance images. ...

Differentiating Sense through Semantic Interaction Data.

Words which have different representations but are semantically related, such as dementia and delirium, can pose difficult issues in understanding tex...

A retrospective study on screening and management of osteoporosis in breast cancer women treated with aromatase inhibitors in Libya.

Negative health effects of aromatase inhibitors (AI) treatments on bones such as osteoporosis are evidenced. This impact of the aromatase inhibitors o...

Early identification of mild cognitive impairment using incomplete random forest-robust support vector machine and FDG-PET imaging.

Alzheimer's disease (AD) is the most common type of dementia and will be an increasing health problem in society as the population ages. Mild cognitiv...

A Wearable Hip Assist Robot Can Improve Gait Function and Cardiopulmonary Metabolic Efficiency in Elderly Adults.

The aims of this paper were to investigate the effectiveness of a newly developed wearable hip assist robot, that uses an active assist algorithm to i...

Deep ensemble learning of sparse regression models for brain disease diagnosis.

Recent studies on brain imaging analysis witnessed the core roles of machine learning techniques in computer-assisted intervention for brain disease d...