Geriatrics

Latest AI and machine learning research in geriatrics for healthcare professionals.

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Subcategories: Alzheimer's Disease Medicare
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An Integrated Molecular Atlas of Alzheimer's Disease

Alzheimer's disease (AD) is a complex neurodegenerative disorder with multifactorial etiology and widespread molecular manifestations. Investigating molecular disease associations in a broader multi-level context across omics modalities remains one central challenge in AD research, despite the increasing availability of large-scale omics data. The AD Atlas, an online multi-omics resource, provides...

Yolo-Key-6D: Single Stage Monocular 6D Pose Estimation with Keypoint Enhancements

Estimating the 6D pose of objects from a single RGB image is a critical task for robotics and extended reality applications. However, state-of-the-art multi stage methods often suffer from high latency, making them unsuitable for real time use. In this paper, we present Yolo-Key-6D, a novel single stage, end-to-end framework for monocular 6D pose estimation designed for both speed and accuracy. Ou...

Mar 4 2026 2603.03879v1
Rethinking the Efficiency and Effectiveness of Reinforcement Learning for Radiology Report Generation

Radiologists highly desire fully automated AI for radiology report generation (R2G), yet existing approaches fall short in clinical utility. Reinforce...

Mar 4 2026 2603.04022v1
Aging Out of the Blue: Estimating and Calibrating Region-specific Epigenetic Clocks for a Blue Zone via SuperLearner

Epigenetic clocks estimate biological age from DNA methylation patterns at CpG sites, providing robust predictions of mortality and morbidity risk. "B...

GEN-KnowRD: Reframing AI for Rare Disease Recognition

Rare diseases affect over 300 million people worldwide, yet patients often endure years-long diagnostic delays that limit timely intervention and tria...

Multi-Omics Integration of Transcriptomics and Metabolomics with Machine Learning Uncovers Novel Risk Factors for Alzheimer's disease

Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, memory impairment, and functional deteriorati...

Retrieving Patient-Specific Radiomic Feature Sets for Transparent Knee MRI Assessment

Classical radiomic features are designed to quantify image appearance and intensity patterns. Compared with end-to-end deep learning (DL) models train...

Mar 2 2026 2603.02367v1
MIRAGE: Knowledge Graph-Guided Cross-Cohort MRI Synthesis for Alzheimer's Disease Prediction

Reliable Alzheimer's disease (AD) diagnosis increasingly relies on multimodal assessments combining structural Magnetic Resonance Imaging (MRI) and El...

Mar 2 2026 2603.02434v1
The Combinatorial Capacity and Robustness of Hierarchical Concept Coding in the Human Medial Temporal Lobe

The human brain encodes a virtually infinite repertoire of semantic concepts using a finite number of neurons, a feat that defies the capacity limits ...

Crop-OCT: a Fully Integrated Imageomics Pipeline to Identify Regional and Focal Retinopathy in Murine Models

Imageomics uses machine learning to accelerate our understanding of biological traits and human disease processes. Some of the earliest imageomics app...

Decomposing response inhibition: a POMDP model

Inhibition is a core cognitive control function whose competence is distributed across the population, with more extreme impairments in psychiatric co...

Align-cDAE: Alzheimer's Disease Progression Modeling with Attention-Aligned Conditional Diffusion Auto-Encoder

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progr...

Mar 2 2026 2603.01552v1
CARE: Towards Clinical Accountability in Multi-Modal Medical Reasoning with an Evidence-Grounded Agentic Framework

Large visual language models (VLMs) have shown strong multi-modal medical reasoning ability, but most operate as end-to-end black boxes, diverging fro...

Mar 2 2026 2603.01607v1
Shape-Interpretable Visual Self-Modeling Enables Geometry-Aware Continuum Robot Control

Continuum robots possess high flexibility and redundancy, making them well suited for safe interaction in complex environments, yet their continuous d...

Mar 2 2026 2603.01751v1
Generative Visual Chain-of-Thought for Image Editing

Existing image editing methods struggle to perceive where to edit, especially under complex scenes and nuanced spatial instructions. To address this i...

Mar 2 2026 2603.01893v1
Differential privacy representation geometry for medical image analysis

Differential privacy (DP)'s effect in medical imaging is typically evaluated only through end-to-end performance, leaving the mechanism of privacy-ind...

Mar 1 2026 2603.01098v1
MINT: Multimodal Imaging-to-Speech Knowledge Transfer for Early Alzheimer's Screening

Alzheimer's disease is a progressive neurodegenerative disorder in which mild cognitive impairment (MCI) marks a critical transition between aging and...

Feb 27 2026 2602.23994v1
Development of a Multi-Trait Polygenic Score for Intrinsic Capacity

Background: Intrinsic capacity (IC) is a key marker of healthy ageing, which captures an individuals physical and mental capacities, measured across f...

AbiOmics: An End-to-End Pipeline to Train Machine Learning Models for Discrimination of Plant Abiotic Stresses Using Transcriptomic Profiling Data

Abiotic stresses are primary constraints on global crop productivity, reducing yields by up to 80%. While traditional phenotypic sensing detects stres...

Developing And Internally Validating AI-Based Aging Resilience Biomarkers in Non-Human Primates

Quantifying biological aging is crucial for understanding functional decline before the onset of morbidity. While many accelerated aging and frailty m...

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