Geriatrics

Machine learning-based LASSO-Cox model for dementia prediction: the role of midlife cardiometabolic, inflammatory, and genetic risk factors in a US cohort.

PURPOSE: We aimed to identify key midlife dementia predictors and develop a novel machine learning (...

Are diagnostic technologies for alzheimer's disease and dementia cost-effective? A systematic review of economic evaluations.

BACKGROUND: Alzheimer's disease (AD) and dementia pose a significant clinical and economic burden gl...

Who is using AI to code? Global diffusion and impact of generative AI.

Generative coding tools promise big productivity gains, but uneven uptake could widen skill and inco...

Novel imidazolium salts bearing 2-oxindoles scaffold as potent acetylcholinesterase inhibitors for Alzheimer's disease: Design, synthesis, in vitro and in silico studies.

In this study, a series of thirty-five novel imidazolium salts bearing a 2-oxindoles were designed a...

Foundation models for electrocardiogram interpretation: clinical implications.

BACKGROUND AND AIMS: The 12-lead electrocardiogram (ECG) remains a cornerstone of cardiac diagnostic...

Explainable Artificial Intelligence for the Mayo Endoscopic Score in Ulcerative Colitis.

INTRODUCTION: The Mayo endoscopic score (MES) is used widely in ulcerative colitis (UC) for severity...

Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer's disease retina.

Chlamydia pneumoniae is an intracellular bacterium implicated in Alzheimer's disease (AD), but its r...

Intelligent decision-making systems for early detection of alzheimer's disease using wearable technologies and deep learning.

Intelligent decision-making systems using wearable electronics and deep learning (DL) might identify...

Predicting fall risk among older adults with sarcopenia in China using machine learning models: a six-year longitudinal study from CHARLS.

The impact of balance exercise on brain age and brain morphometry: insights from MRI analysis.

Physical exercise is known to delay the cognitive decline in the elderly. However, the effect of low...

A Framework for Healthcare from the Eye: Oculomics as a Powerful Window to Systemic Health.

PURPOSE: To present a comprehensive framework for integrating oculomics to assess ocular and systemi...

Early diagnosis of Alzheimer's disease from functional rs-fMRI images based on deep learning networks and transfer learning approach.

Exploiting deep learning methods to accelerate the analysis of medical images and the interpretation...

An integrative multiomics random forest framework for robust biomarker discovery.

BACKGROUND: High-throughput technologies now produce a wide array of omics data, from genomic and tr...

Current Status of AI-Assisted Screening for Opportunistic Osteoporosis.

Large Language Models Improve Scene Invariant Detection of Behaviours of Risk in Dementia Residential Care Across Multiple Surveillance Camera Views.

Behavioural and psychological symptoms of dementia pose challenges to the safety and well-being of i...

A multi-view DTI feature fusion framework for enhanced diagnosis of Alzheimer's disease.

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder. Diffusion tensor imaging (DT...

Neural-linguistic analysis for Alzheimer's detection: A deep learning approach informed by cognitive neuroscience.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that disrupts cognitive functio...

LungSurg: A Generative AI System for Segmentation and Phase Classification in Thoracoscopic Lobectomy.

The integration of artificial intelligence (AI) into surgical practices is advancing towards greater...

Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression.

PURPOSE: Aging and metabolic syndrome (MetS) are intertwined risk factors for breast cancer (BC), bu...

Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging.

Understanding how pancreas size and shape change with normal aging is critical for establishing a ba...

inMOTIFin: a lightweight end-to-end simulation software for regulatory sequences.

SUMMARY: The accurate development, assessment, interpretation, and benchmarking of bioinformatics fr...