Geriatrics

Latest AI and machine learning research in geriatrics for healthcare professionals.

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Showing 61-80 of 9,900 articles

Computational precision nutrition for sarcopenia and associated multimorbidity in ageing.

Sarcopenia is the age-related progressive decline in both skeletal muscle mass and function. It acts as an exacerbator of multimorbidity, engaging in bidirectional pathological cycles with multiple chronic diseases, and contributes substantially to increased mortality, disability and healthcare costs. Current nutritional support is often limited by a generic one-size-fits-all approach that fails t...

Aug 26 2026 42648442

Deep learning-derived magnetic resonance imaging masseter muscle volume is associated with oral impairment and cognitive frailty in older Japanese adults.

BACKGROUND AND OBJECTIVES: The masseter muscle is associated with oral impairment and age-related functional decline, yet scalable and objective indicators remain limited in epidemiological studies. We developed a convolutional neural network (CNN) to segment the masseter muscle on T1-weighted magnetic resonance images (T1WI) and examined whether CNN-derived masseter muscle volume, as an imaging-b...

Aug 26 2026 42648504
Association between body composition and recurrence in stage II-III colon cancer: a retrospective cohort study.

INTRODUCTION: Colorectal Cancer (CRC) is a common cause of cancer death and prognostic factors are used to determine management. Patients with advance...

Aug 26 2026 42648596
Integrated bulk and single-cell transcriptomic analyses identify senescence-related hub genes and microenvironmental remodeling in sarcopenia.

Increasing evidence indicates that cellular senescence, metabolic dysfunction, stromal remodeling, and immune perturbation collectively contribute to ...

Aug 26 2026 42642681
Fatty Acid Signatures as Nutritional Indices: Molecular Gateways to Health, Aging, and Functional Food Innovation.

Fatty acid signatures (FA signatures), defined as the relative distribution of saturated, monounsaturated, and polyunsaturated fatty acids within spec...

Aug 26 2026 42657240
Identification of Aging and Mitochondria-Related Hub Genes in Dilated Cardiomyopathy.

Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and systolic dysfunction and is associated with mitochondrial dysfunction a...

Aug 25 2026 42644501
Understanding the Functional Needs of Patients With Cardiovascular Disease Regarding Nursing Robots Using a Kano Survey Scale: Cross-Sectional Study.

BACKGROUND: With population aging and the growing burden of chronic diseases, the number of patients with cardiovascular disease (CVD) in China contin...

Aug 25 2026 42640686
Manifold representation learning for Alzheimer's disease detection with EEG-based functional brain connectivity.

Alzheimer's disease (AD) is a common neurodegenerative disease characterized by severe cognitive dysfunctions and brain disorders. The emergence of de...

Aug 25 2026 42641910
Performance-Based Frailty Tools Capture Distinct Risk Phenotypes in Kidney Transplant Candidates: A Comparative Analysis of FRAIL and SPPB.

Frailty predicts adverse outcomes in kidney transplant candidates, but it remains unclear whether different frailty tools identify the same or distinc...

Aug 25 2026 42641925
An Umbrella Review of Artificial Intelligence Applications in Mental Health Care.

BACKGROUND: Artificial intelligence (AI) is increasingly used in mental health care to address rising demand, workforce shortages and access barriers;...

Aug 24 2026 42635445
Preventing fragility fractures: AI-based opportunistic osteoporosis detection in routine CT ​.

UNLABELLED: This study shows that an artificial intelligence tool can identify patterns of reduced bone mineral density in routine CT scans that would...

Aug 24 2026 42635729
Bridging the gap: predicting early contingency management outcomes.

Background: Contingency management (CM) is a psychosocial treatment used to improve socially significant behaviors. Its efficacy has been demonstrated...

Aug 24 2026 42636295
Stress hyperglycaemia ratio and post-operative delirium after cardiac surgery: a retrospective cohort study of the MIMIC-IV database.

BACKGROUND: Post-operative delirium is a serious neurocognitive complication of cardiac surgery. The stress hyperglycaemia ratio (SHR), which adjusts ...

Aug 23 2026 42633982
Apigenin Alleviates Ligamentum Flavum Ossification by Dual-Targeting CA9 and CDK6 and Modulating Calcium/PI3K-Akt Signaling.

While apigenin shows therapeutic potential for bone-related disorders like osteoporosis and osteoarthritis, its mechanisms in regulating ligamentum fl...

Aug 22 2026 42631587
Osteosarcopenia Revisited: From Mechanisms to Management.

Sarcopenia and osteoporosis are characterized by insufficient mass and function of skeletal muscle and bone, and often co-occur in older persons, a co...

Aug 22 2026 42631701
Triglyceride-glucose frailty index, metabolic-frailty phenotypes, and mortality in critically ill patients with acute kidney injury: Derivation, interpretation, and external validation.

BACKGROUND: Prognosis remains heterogeneous among critically ill patients with acute kidney injury (AKI). We evaluated the triglyceride-glucose frailt...

Aug 22 2026 42632433
Comparative Performance of Multimodal Large Language Models in Grayscale Ultrasound-Based Classification of Thyroid Nodules.

BACKGROUND: Multimodal large language models (LLMs) are increasingly being explored for medical image analysis, but their relative performance in thyr...

Aug 22 2026 42632527
Ensemble DNA methylation clock demonstrates Immune-metabolic Aging signatures associated with Mortality.

Aging is a multifactorial process that is best described in terms of the progressive acquisition of multiple layers of phenotypic changes, such as epi...

Aug 22 2026 42632601
Readability and Quality of Large Language Model Patient Education for Trigeminal Neuralgia: A Cross-Sectional Study.

Large language models (LLMs) are increasingly used for patient health education, yet the readability and educational quality of LLM-generated informat...

Aug 21 2026 42631603
Bioinformatics analysis reveals shared gene signatures and molecular mechanisms between periodontitis and rheumatoid arthritis in the context of aging.

OBJECTIVE: The interplay between periodontitis (PD) and rheumatoid arthritis (RA) is well recognized, with aging being a central risk factor for both....

Aug 21 2026 42627218
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