Geriatrics

Discovery of novel cathepsin K inhibitors for osteoporosis treatment using a deep learning-based strategy.

BACKGROUND: Cathepsin K (CTSK), a cysteine protease of the papain family, exhibits high expression i...

Clinical validation of AI assisted animal ultrasound models for diagnosis of early liver trauma.

The study aimed to develop an AI-assisted ultrasound model for early liver trauma identification, us...

Parsimonious and explainable machine learning for predicting mortality in patients post hip fracture surgery.

Hip fractures among the elderly population continue to present significant risks and high mortality ...

A novel neuroimaging based early detection framework for alzheimer disease using deep learning.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that significantly impacts cogn...

The impact of intelligent devices utilization on household medical expenditure of older adults in China.

With the rapid development of artificial intelligence, there is an increasing utilization of intelli...

Classifying and diagnosing Alzheimer's disease with deep learning using 6735 brain MRI images.

Traditional diagnostic methods for Alzheimer's disease often suffer from low accuracy and lengthy pr...

End-to-end feature fusion for jointly optimized speech enhancement and automatic speech recognition.

Speech enhancement (SE) and automatic speech recognition (ASR) in real-time processing involve impro...

A multi-modal graph-based framework for Alzheimer's disease detection.

We propose a compositional graph-based Machine Learning (ML) framework for Alzheimer's disease (AD) ...

Exploring the link between the ZJU index and sarcopenia in adults aged 20-59 using NHANES and machine learning.

Sarcopenia, characterized by progressive loss of muscle mass and function, is a growing public healt...

Risk factors and prediction of distant metastasis (DM) of colon adenocarcinoma: a logistic regression and machine learning study based on surveillance, epidemiology, and end results (SEER) database.

Radiomics and machine learning for osteoporosis detection using abdominal computed tomography: a retrospective multicenter study.

OBJECTIVE: This study aimed to develop and validate a predictive model to detect osteoporosis using ...

Exploring the spatiotemporal influence of climate on American avian migration with random forests.

Birds have adapted to climatic and ecological cycles to inform their Spring and Fall migration timin...

Long-wave infrared computational multispectral metasurface and spectral reconstruction method.

We demonstrate a computational multispectral metasurface employing a 3×3 photonic crystal array arch...

Evaluation of MRI-based synthetic CT for lumbar degenerative disease: a comparison with CT.

Patients with lumbar degenerative disease typically undergo preoperative MRI combined with CT scans,...

Machine learning for Parkinson's disease: a comprehensive review of datasets, algorithms, and challenges.

Parkinson's disease (PD) is a devastating neurological ailment affecting both mobility and cognitive...

DeepLASD countermeasure for logical access audio spoofing.

Voice-based authentication systems have become increasingly vulnerable to logical access (LA) spoofi...

Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome.

Extracellular vesicles (EVs) in plasma are composed of exosomes, microvesicles, and apoptotic bodies...

Potential role of TNFRSF12A in linking glioblastoma and alzheimer's disease via shared tumour suppressor pathways.

Tumor suppressor genes (TSGs) are critical regulators of cellular homeostasis and are extensively st...

Identification of key genes associated with cellular aging and mitochondria in acute myocardial infarction.

Acute myocardial infarction (AMI) poses a significant global mortality burden. Utilizing bio informa...

Developed a knowledge base of risk factors for postoperative cognitive dysfunction: a retrospective database study.

Postoperative cognitive dysfunction (POCD), a heterogeneous spectrum of surgery/anesthesia-associate...

Prediction of cardiovascular diseases based on GBDT+LR.

Currently, there are over 300 million patients with cardiovascular diseases in China. With the accel...