Ophthalmology

Glaucoma

Latest AI and machine learning research in glaucoma for healthcare professionals.

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Predicting Retinal Nerve Fiber Layer Thickness From Ocular Hypertension Treatment Study Optic Disc Photographs.

IMPORTANCE: Deep learning predictions of retinal nerve fiber layer (RNFL) thickness derived from optic disc photographs may help to determine risk for development of primary open-angle glaucoma (POAG) in patients with ocular hypertension.

Jun 26 2025 40569586

Evaluating real-world performance of an automated offline glaucoma AI on a smartphone fundus camera across glaucoma severity stages.

PURPOSE: Leveraging an artificial intelligence system (AI) for glaucoma screening can mitigate the current challenges and provide prompt detection and management crucial in averting irreversible blindness. The study reports the real-world performance of a glaucoma AI system deployed on a smartphone-based fundus camera across various severities of glaucoma.

Jun 26 2025 40569941
Topo-CNN: Retinal Image Analysis with Topological Deep Learning.

The analysis of fundus images is vital for early detection of retinal diseases such as diabetic retinopathy (DR), glaucoma, and age-related macular de...

Jun 25 2025 40563040
Macular pigment optical density and measurement technology based on artificial intelligence: a narrative review.

Macular pigment (MP) is a crucial pigment in the macular region. It plays an important role in filtering blue light, and exhibits anti-inflammatory an...

Jun 18 2025 40534793
Artificial intelligence for glaucoma.

This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: To determine the accuracy of artificial intelligence (AI) algori...

Jun 17 2025 40525544
Retinal Vessel Traits and Age-Related Eye Disease in the Canadian Longitudinal Study on Aging.

BACKGROUND: To cross-sectionally and longitudinally examine whether retinal vessel traits are associated with glaucoma-related outcomes (glaucoma, cup...

Jun 14 2025 40515626
Unsophisticated AI coaching does not improve performance on symptom and performance validity tests in a Romanian sample of experimental feigners.

The present study aimed to investigate the ability of symptom and performance validity indicators to detect experimental feigning with symptom-coachin...

May 31 2025 40448613
Glaucoformer: Dual-domain Global Transformer Network for Generalized Glaucoma Stage Classification.

Classification of glaucoma stages remains challenging due to substantial inter-stage similarities, the presence of irrelevant features, and subtle les...

May 29 2025 40440150
Ophthalmic Image Synthesis and Analysis with Generative Adversarial Network Artificial Intelligence.

Generative adversarial networks (GANs), introduced by Ian Goodfellow in 2014, have revolutionized adversarial machine learning, particularly in data s...

May 20 2025 40394320
An Artificial Intelligence Method for Phenotyping of OCT-Derived Thickness Maps Using Unsupervised and Self-supervised Deep Learning.

The objective of this study is to enhance the understanding of ophthalmic disease physiology and genetic architecture through the analysis of optical ...

May 20 2025 40394321
Analysis of Standard Automated Visual Field Tests in Glaucoma and the Role of Facial Contour.

PRCIS: Using a CNN-enhanced platform, 60-4 visual fields identified peripheral glaucomatous defects missed by central testing in mild cases; facial co...

May 19 2025 40377481
Synergistic AI-resident approach achieves superior diagnostic accuracy in tertiary ophthalmic care for glaucoma and retinal disease.

INTRODUCTION: Artificial intelligence (AI) shows promise in ophthalmology, but its potential in tertiary care settings in Latin America remains unders...

May 19 2025 40458618
State of the Art on Inherited Retinal Dystrophies: Management and Molecular Genetics.

Inherited retinal dystrophies (IRDs) represent a group of heterogeneous disorders caused by gene mutations primarily affecting retinal photoreceptors....

May 18 2025 40429522
Restoring AIBP expression in the retina provides neuroprotection in glaucoma.

Glaucoma is a neurodegenerative disease manifested by retinal ganglion cell (RGC) death and irreversible blindness. We have identified apolipoprotein ...

May 9 2025 40349106
Keypoint localization and parameter measurement in ultrasound biomicroscopy anterior segment images based on deep learning.

BACKGROUND: Accurate measurement of anterior segment parameters is crucial for diagnosing and managing ophthalmic conditions, such as glaucoma, catara...

May 6 2025 40329288
Prediction of perimetric progression in ocular hypertension and open angle glaucoma based on corneal biomechanics.

PurposeTo identify parameters that are significant risk predictors of visual field (VF) progression in patients with ocular hypertension (OHT) or earl...

May 6 2025 40329632
Deep learning-assisted 10-μL single droplet-based viscometry for human aqueous humor.

Probing the viscosity of human aqueous humor is crucial for optimizing micro-tube shunts in glaucoma treatment. However, conventional viscometers are ...

May 2 2025 40359807
Enhanced glaucoma classification through advanced segmentation by integrating cup-to-disc ratio and neuro-retinal rim features.

Glaucoma is a progressive eye condition caused by high intraocular fluid pressure, damaging the optic nerve, leading to gradual, irreversible vision l...

Apr 28 2025 40315660
Risk for ocular hypertension progression to early glaucoma: A predictive model and key predictors.

BACKGROUND: Ocular hypertension (OHT) is the most significant risk factor for glaucoma. We aimed to develop a model for predicting OHT progression to ...

Apr 28 2025 40306393
Optimized glaucoma detection using HCCNN with PSO-driven hyperparameter tuning.

. This study is focused on creating an effective glaucoma detection system employing a Hybrid Centric Convolutional Neural Network (HCCNN) model. By u...

Apr 22 2025 40194525
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