Transplantation

Heart Transplantation

Latest AI and machine learning research in heart transplantation for healthcare professionals.

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Single-Cell Multi-Omics Dissection of Malignant Evolutionary Mechanisms and Construction of a Prognostic Model for Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) exhibits pronounced heterogeneity across WHO histological grades, yet systematic single-cell multi-omics studies characterizing these transitions remain limited. We integrated scRNA-seq and scATAC-seq data across ccRCC WHO grades to establish a multi-omics framework encompassing tumor cells and immune populations. Using pseudotime trajectory analysis and mac...

Closed-Loop Quality Assurance for Production Clinical AI Documentation

A closed-loop quality system deployed across thirteen US hospital sites resolved physician complaints with zero regressions on 42 tracked cases across 1,089 optimization iterations, while a deterministic assembly-agent replacement cut H+P trace latency from 19.6 s to 10.8 s (-8.8 s, 95% CI [-10.5, -7.1] s; n = 100 pre, n = 100 post). We report four observations and an architectural follow-through....

Distinct afferent signatures onto anterior and posterior VMHvl subdomains and their progesterone receptor-expressing neurons

Female sexual behavior is fundamentally coupled to reproductive state, requiring the dynamic and coordinated regulation of sexual receptivity and reje...

Towards Open-World Referring Expression Comprehension: A Benchmark with Training-free Multi-task Consistency Checker

Referring expression comprehension (REC) aims to localize a target object within an image based on a given expression. Although recent advances in vis...

May 25 2026 2605.25706v1
Pixel-Level Pavement Distress Assessment Using Instance Segmentation

Automated pavement distress assessment requires more than image-level classification or coarse bounding box detection, demanding precise localization ...

May 25 2026 2605.26095v1
DigitAb: Domain-Adaptive Cell Type Prediction Method from Light Microscopy Images

Light microscopy imaging with histological stains is central to disease diagnosis and research. It is enhanced with immunostaining to reveal cellular ...

Effects of Structural Reward Shaping on Biophysical Properties in RL-Trained Plasmid Generators

We compare the efficacy and distributional effects of supervised fine-tuning (SFT) and reinforcement learning (RL) post-training for PlasmidGPT, a fou...

CasualSynth: Generating Structurally Sound Synthetic Data

Large Language Models (LLMs) generate realistic synthetic data but offer no guarantee that their outputs respect the causal mechanisms governing the t...

May 17 2026 2605.17528v1
SIGNAL: A Scalable, Real-World Model for Rapid Intraoperative Molecular Classification of Gliomas Using Stimulated Raman Histology

Background: Previous machine learning models to intraoperatively predict the molecular status of gliomas using stimulated Raman histology (SRH), such ...

Systematic toxicological study of PFOS/PFOA co-exposure driving prostate cancer: Core target identification, TME immune remodeling, and combination drug prediction

Background: Per- and polyfluoroalkyl substances (PFAS), particularly perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), are persisten...

Causal-Aware Foundation-Model for Bilevel Optimization in Discrete Choice Settings

We introduce a causal aware foundation-model framework for real time optimal decision making in discrete choice environments. We propose a constrained...

May 7 2026 2605.06941v1
Self Driving Datasets: From 20 Million Papers to Nuanced Biomedical Knowledge at Scale

Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature,...

May 7 2026 2605.07022v1
Selfie-Capture Dynamics as an Auxiliary Signal Against Deepfakes and Injection Attacks for Mobile Identity Verification

Mobile remote identity verification (RIdV) systems are exposed to attacks that manipulate or replace the facial video stream, including presentation a...

Apr 30 2026 2605.00218v1
DeepTaxon: An Interpretable Retrieval-Augmented Multimodal Framework for Unified Species Identification and Discovery

Identifying species in biology among tens of thousands of visually similar taxa while discovering unknown species in open-world environments remains a...

Apr 27 2026 2604.24029v1
Identity-Decoupled Anonymization for Visual Evidence in Multi-modal Retrieval-Augmented Generation

Multi-modal retrieval-augmented generation (MRAG) systems retrieve visual evidence from large image corpora to ground the responses of large multi-mod...

Apr 26 2026 2604.23584v1
Housekeeping Gene Expression Normalization in Transcriptomics Mitigates Data Leakage in Machine Learning Models

Background: Inappropriate normalization can lead to data leakage and overfitting in machine learning models. Accurately identifying housekeeping genes...

Speculative Decoding for Autoregressive Video Generation

Autoregressive video diffusion is emerging as a promising paradigm for streaming video synthesis, with step distillation serving as the primary means ...

Apr 19 2026 2604.17397v1
Protocol for LLM-Generated CONSORT Report for Increased Reporting: A Parallel-Arm Randomized Controlled Trial (Protocol)

Background Randomized controlled trials (RCTs) often have incomplete methods reporting despite widespread adoption of the CONSORT guideline. The edito...

Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; yet substantial proportion of patients exhibit intrinsic or acquired resistance, ...

Apr 7 2026 2604.05478v1
Real-Time Surrogate Modeling for Personalized Blood Flow Prediction and Hemodynamic Analysis

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascul...

Apr 3 2026 2604.03197v1
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