Heart Transplantation

Deep-LUMEN assay - human lung epithelial spheroid classification from brightfield images using deep learning.

Three-dimensional (3D) tissue models such as epithelial spheroids or organoids have become popular for pre-clinical drug studies. In contrast to 2D monolayer culture, the characterization of 3D tissue models from non-invasive brightfield images is a significant challenge. To address this issue, here we report a deep-learning uncovered measurement of epithelial networks (Deep-LUMEN) assay. Deep-LUM...

Dermoscopic Features of Giant Molluscum Contagiosum in a Patient with Acquired Immunodeficiency Syndrome.

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to typical molluscum contagiosum, dermoscopic features of giant lesions have been poorly described, and none of the reports included multiple giant lesions in an immunocompromised patient. We present a patient with acquired immunodeficiency syndrome di...

A fatal invasive pulmonary infection in an adult patient with malignant lung adenocarcinoma.

BACKGROUND AND PURPOSE: complex as a ubiquitous environmental mold is increasingly reported to cause an invasive fungal infection in immunosuppressiv...

Artificial neural network and bioavailability of the immunosuppression drug.

PURPOSE OF REVIEW: The success of organ transplant is determined by number of demographic, clinical, immunological and genetic variables. Artificial i...

Can Machine Learning Improve Screening for Targeted Delinquency Prevention Programs?

The cost-effectiveness of targeted delinquency prevention programs for children depends on the accuracy of the screening process. Screening accuracy i...

Iatrogenic Cushing's syndrome as a consequence of nasal use of Betamethasone spray during pregnancy.

INTRODUCTION: Glucocorticoids (GC) are largely used for their anti-inflammatory and immunosuppressive effects. Until recently "local" administration (...

Graft Rejection Prediction Following Kidney Transplantation Using Machine Learning Techniques: A Systematic Review and Meta-Analysis.

Kidney transplantation is recommended for patients with End-Stage Renal Disease (ESRD). However, complications, such as graft rejection are hard to pr...

Results of a Literature Review to Prepare Data Modelling in the Context of Kidney Transplant Rejection Diagnosis.

Due to demographic change the number of serious kidney diseases and thus required transplantations will increase. The increased demand for donor organ...

Evaluation of Cyclosporine Pharmacokinetic, Monitoring, and Dosing Parameters for GVHD Prophylaxis in Hematopoietic Stem Cell Transplant (HSCT) Recipients.

Allogeneic hematopoietic stem cell transplantation (AHSCT) is a major method of treatment for different hematologic and congenital disease. Graft vers...

Treatment of Chylothorax with Pleurodesis (A Lesser Known Complication of Behçet's Disease): A Case Report.

Behçet's Disease (BD) is a multisystemic vasculitis which usually affects optical, genital, and oral mucosae and often reoccurs intermittently. Chylot...

A hybrid active force control of a lower limb exoskeleton for gait rehabilitation.

Owing to the increasing demand for rehabilitation services, robotics have been engaged in addressing the drawbacks of conventional rehabilitation ther...

Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online.

BACKGROUND: Immunosuppressant Bayesian dose adjustment (ISBA) is an online expert system, routinely used by approximately 140 transplantation centers ...

Analysis of Interleukin-17 mRNA Level in the Urinary Cells of Kidney Transplant Recipients with Stable Function.

OBJECTIVES: Kidney transplantation supports patients with end-stage kidney diseases. Many factors control the allograft function in kidney transplant ...

Parsing Based on Parselets: A Unified Deformable Mixture Model for Human Parsing.

Human parsing, namely partitioning the human body into semantic regions, has drawn much attention recently for its wide applications in human-centric ...

Effects of Phenylglyoxal and N-ethylmaleimide Concentration on Mycophenolic Acid Production by ATCC16024.

Mycophenolic acid is a secondary extracellular metabolite of strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive...

Accidental Overdose of Oral Cyclosporine in Haematopoietic Stem Cell Transplantation: A Case Report and Literature Review.

A 26-year-old woman developed symptoms of acute toxicity during cyclosporine (CsA) therapy for graft-versus-host disease prophylaxis. The standard reg...

[Analysis of Cases with Elevated Blood (1->3)-β-D-glucan in Relation to an Infection Marker, Neutrophil CD64 Expression].

(1->3)-β-D-glucan (BDG) is a constituent of the fungal cell wall and its blood level is known as a marker of fungal infection including pneumocystis p...

Regularised extreme learning machine with misclassification cost and rejection cost for gene expression data classification.

The main purpose of traditional classification algorithms on bioinformatics application is to acquire better classification accuracy. However, these a...

[A case report of hepatitis B virus reactivation in a hepatitis B core antibody-positive, hepatitis B surface antigen-negative hemodialysis patient].

Reactivation of the hepatitis B virus (HBV) has been reported in patients receiving immunosuppressive therapy or chemotherapy. We report a case of HBV...