Hematology

Latest AI and machine learning research in hematology for healthcare professionals.

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Machine Learning for Intraoperative Bleeding Prediction in Patients Undergoing Surgery: Scoping Review.

BACKGROUND: Intraoperative bleeding is a critical event that impacts surgical safety and patient outcomes. Machine learning (ML) has demonstrated potential in prediction tasks, yet its methodological rigor and clinical translation face challenges. OBJECTIVE: This scoping review aims to systematically synthesize the current state of development, performance, and validation of ML models for predicti...

Jun 10 2026 42269098

Genomics of Dendritic Cell Pyruvate Metabolism Reveals Stage-Associated Circulating Immune Signatures in Diabetic Retinopathy.

BACKGROUND: The role of circulating pyruvate in diabetic retinopathy (DR) progression is poorly defined. Unravelling its cell-specific genomic regulation is vital. METHODS: Integrative genomics analysis combined two-sample Mendelian randomization (MR) to evaluate the association between circulating pyruvate and DR risk with single-cell RNA sequencing (scRNA-seq) metabolic profiling in peripheral b...

Jun 10 2026 42270003
HeLP-BAG score: a novel data-driven scoring system for predicting post-operative 30-day mortality using 24-hour preoperative data.

BACKGROUND: Accurate preoperative risk stratification remains challenging, as existing scoring systems are often complex, invasive, or limited to spec...

Jun 9 2026 42260375
Age-stratified risk profiles for emergency colorectal cancer resection: A machine-learning analysis.

BACKGROUND: Emergency colorectal cancer resection (ECCR) is associated with worse perioperative and oncologic outcomes than elective surgery. As the i...

Jun 9 2026 42263377
Prediction of avatrombopag-induced thrombocytosis in pediatric immune thrombocytopenia: an AI-based real-world study.

Avatrombopag (AVA), an oral thrombopoietin receptor agonist (TPO-RA), has demonstrated favorable efficacy in the treatment of pediatric immune thrombo...

Jun 9 2026 42260021
Progress of Traditional Chinese Medicine in Targeting Ferroptosis to Combat Cerebral Ischemia-Reperfusion Injury.

Cerebral ischemia-reperfusion injury (CIRI) often results in significant morbidity and mortality. The effectiveness of current reperfusion therapies i...

Jun 8 2026 42261256
Development and Validation of a Novel Risk Prediction Model for Incident Diabetic Foot Complications: A Large, Longitudinal, Population-Based Machine Learning Study.

OBJECTIVE: Diabetic foot complications (DFCs) are common diabetes complications. Existing tools for predicting incident DFCs remain insufficient. This...

Jun 8 2026 42253099
Pancreatic Cancer Risk Stratification Across Diabetes Stages: Development and Internal Validation of a Machine Learning Model.

BACKGROUND: Pancreatic cancer is diagnosed at advanced stages in diabetes patients. Existing prediction models require complete historical data and fo...

Jun 8 2026 42257579
Impact of middle meningeal artery embolization on neurological complications and discharge outcomes in chronic subdural hematoma: A machine learning-based comparative study.

INTRODUCTION: Chronic subdural hematoma (cSDH) predominantly affects older adults, often those with prior head trauma, anticoagulation therapy, or chr...

Jun 8 2026 42257776
Machine Learning and AI Applied to fNIRS Data Reveals Novel Brain Activity Biomarkers in Stable Subclinical Multiple Sclerosis.

People with Multiple Sclerosis (MS) complain of problems with hand dexterity and cognitive fatigue. However, in many cases, impairments are subtle and...

Jun 8 2026 42258691
Deep Learning Predicts Mutations and Outcomes in Gastrointestinal Stromal Tumors from Whole-Slide Images.

Gastrointestinal stromal tumor (GIST) is the most common gastrointestinal mesenchymal tumor, driven by tyrosine-protein kinase (KIT) and platelet-deri...

Jun 8 2026 42258704
Multiobjective blood pump impeller optimization with three response surface methods and prototype stator casting for an integrated motor pump.

Cardiovascular diseases are a leading cause of mortality worldwide; rotary blood pumps are a key therapy. Prior optimization studies often treated few...

Jun 8 2026 42259877
Transferrin Receptor 1 (TFRC) and Ferroptosis-Related Biomarkers in Oncology: Analytical Evaluation and Translational Potential.

One of the important regulators of cellular iron uptake is transferrin receptor 1 (TFRC), which is closely linked to ferroptosis, an iron-dependent fo...

Jun 6 2026 42249840
Large language models for generating longitudinal synthetic data in low-risk pregnancy care.

This article describes an obstetric dataset covering the full continuum of care of 5000 synthetic low-risk pregnant women, from preconception to post-...

Jun 5 2026 42317631
End to End Proximal Anastomosis is the Sole Modifiable Variable in Risk Score for Loss of Patency of Aortobifemoral Artery Bypass After Index Operative Hospitalization.

OBJECTIVE: The purpose of this study was to create a risk score for loss of aorto-bifemoral artery bypass (ABF) patency utilizing preoperative, periop...

Jun 5 2026 42250825
Development and validation of a machine learning-based prediction model for malnutrition risk in peritoneal dialysis patients: a multi‑center retrospective study.

PURPOSE: To develop and validate a machine learning (ML)‑based model for predicting malnutrition risk in patients undergoing maintenance peritoneal di...

Jun 5 2026 42247202
Performance Evaluation of GPT-5, Grok 4, and DeepSeek R1 in Interpreting Complete Blood Count Reports for Hematologic Diseases: Retrospective Comparative Study.

BACKGROUND: Large language models (LLMs) demonstrate potential in the laboratory, yet rigorous clinical evaluation remains limited. The opacity of LLM...

Jun 5 2026 42247415
Multidimensional proteomics and explainable AI feature selection identify cross-platform lung cancer molecular signature in blood plasma.

BACKGROUND: Lung cancer is the leading cause of cancer mortality worldwide despite the availability of low-dose computed tomography (LDCT) for screeni...

Jun 5 2026 42249069
Artificial intelligence for the prediction of prognosis in colorectal cancer patients using routine blood indices.

Overall survival (OS) of colorectal cancer (CRC) patients remains suboptimal, especially in advanced disease. This study aimed to construct and valida...

Jun 5 2026 42249119
Development, internal testing, and external validation of an interpretable machine-learning model for predicting imaging-confirmed in-hospital postoperative deep vein thrombosis in older patients with patellar fractures.

BACKGROUND: Older patients with patellar fractures may be at increased risk of postoperative deep vein thrombosis (DVT) because of trauma, perioperati...

Jun 5 2026 42249366
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