Hematology

Decoding Allosteric Inhibition in MALT1: The Hidden Role of Conformational Plasticity in Metastable States via Biased MD and Deep Learning.

The mucosa-associated lymphoid tissue lymphoma-translocation protein 1 (MALT1) is a key protein in t...

Machine learning prediction for AML based on 3D genome selected circRNA.

Acute myeloid leukemia (AML) is a clinically aggressive hematologic malignancy driven by complex gen...

Evaluation of three artificial intelligence chatbots for generating clinical hematology multiple choice questions for medical students.

Prediction of myeloid malignant cells in Fanconi anemia using machine learning.

Fanconi anemia (FA) is an inherited bone marrow failure syndrome with cancer predisposition. Most FA...

Cell death-related gene signatures as dual-function biomarkers: Early diagnosis and therapeutic targeting in Staphylococcus aureus pneumonia.

BACKGROUND: Staphylococcus aureus (S. aureus) pneumonia constitutes a lethal respiratory infection w...

The effect of air pollution and household environmental indicators on anemia status among under-five children in low-middle income countries: exploring potential machine learning applications on demographic and health surveys.

Exposure to air pollution has been associated with anemia in children, but little effort has been ma...

Transformer-based feature extraction approach for hematopoietic cancer subtype classification.

Accurate classification of hematopoietic cancer subtypes remains challenging due to the multipotent ...

Machine learning integrating MRI and clinical features predicts early recurrence of hepatocellular carcinoma after resection.

This study aims to construct a robust artificial intelligence (AI) model to predict early recurrence...

Identifying the state of cerebrovascular autoregulation using the pressure reactivity index versus the mean flow index: Why metric matters.

Cerebral autoregulation maintains stable cerebral blood flow despite fluctuations in cerebral perfus...

Boosting angiogenesis experimentally in ovo by biofunctionalizing collagen membranes with platelet-rich fibrin and hyaluronic acid: implications for regenerative oral surgery?

PURPOSE: Biocompatible collagen membranes (CM) are widely used in regenerative dentistry, particular...

Association of depressive symptoms with systemic immune-inflammation index and platelet parameters among survivors of myocardial infarction: a cross-sectional NHANES study enhanced by machine learning and SHAP analysis.

BACKGROUND: Inflammation is implicated in the elevated risk of depressive disorder following myocard...

Associations of blood cell indices with the severity of rheumatoid arthritis: a retrospective case-control and machine learning modeling study.

BACKGROUND: Immune cells are involved in rheumatoid arthritis (RA), but the link between other blood...

Non-invasive blood pressure monitoring using wearables for cardiovascular risk assessment: a systematic review.

PURPOSE: Cardiovascular diseases are the leading causes of mortality in women worldwide, with hypert...

Development of Venous Thromboembolism Risk Prediction Models Based on Whole Blood Gene Expression Profiling Using 20 Machine Learning Algorithms: Comprehensive Analysis Study.

BACKGROUND: There is a lack of venous thromboembolism (VTE) risk prediction models based on gene exp...

AI-assisted preoperative planning combined with robotic-assisted total knee arthroplasty vs. conventional surgery: a retrospective controlled study.

OBJECTIVE: To compare perioperative outcomes and early functional recovery between AI-robotic and co...

Diagnostic Accuracy of the National Library of Medicine (NLM) Screener Application in Screening for Malaria Parasites Among Blood Donors at the Korle-Bu Blood Bank, Ghana: A Cross-Sectional Study.

BACKGROUND AND AIMS: Malaria is a deadly disease spread through the bite of an infected female Anoph...

Integrative Bioinformatics and Machine Learning Identify Novel Diagnostic Biomarkers and Molecular Mechanisms in Sjögren's Syndrome.

BACKGROUND: Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by significant di...

Integrating CAR-T therapy with PD-1/PD-L1 blockade: Mechanisms, synergy, and optimized strategies in NSCLC.

Non-small cell lung cancer (NSCLC) presents persistent challenges in immunotherapy, as the clinical ...

Dynamic Ensemble Selection for Early Detection of Deep Vein Thrombosis in Fracture Patients.

Deep vein thrombosis (DVT) in fracture patients is often clinically silent, with a high incidence of...

Assessment of AI-generated responses to common pregnancy questions: A blinded expert evaluation.

INTRODUCTION: We conducted a cross-sectional, blinded expert evaluation of AI-generated answers to 2...

Components of metabolic syndrome affect COVID-19 outcomes via platelet aggregation.

BACKGROUND: Emerging evidence suggests that platelet activation and aggregation are common factors i...